Zobrazeno 1 - 10
of 130
pro vyhledávání: '"Jaap A, Bakker"'
Autor:
Maurice J. Huizing, Moreyba Borges-Luján, Giacomo Cavallaro, Gema E. González-Luis, Genny Raffaeli, Pilar Bas-Suárez, Jaap A. Bakker, Rob M. Moonen, Eduardo Villamor
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Background: Amino acids are increasingly recognized as bioactive molecules in numerous physiological and pathophysiological pathways. The non-essential amino acid glutamate is vasoactive in the rat ductus arteriosus (DA) and a decrease in its levels
Externí odkaz:
https://doaj.org/article/54d08100fa4b4d8d91268eb9a850bd4e
Autor:
Anouk C.M. Platteel, Brigitte A. Wevers, Johan Lim, Jaap A. Bakker, Hetty J. Bontkes, Joyce Curvers, Jan Damoiseaux, Michiel Heron, Gijs de Kort, Maarten Limper, Ellen G. van Lochem, A.H. Leontine Mulder, Christiaan G.J. Saris, Hester van der Valk, Anneke J. van der Kooi, Ester M.M. van Leeuwen, Marcel Veltkamp, Marco W.J. Schreurs, Bob Meek, Dörte Hamann
Publikováno v:
Journal of Translational Autoimmunity, Vol 2, Iss , Pp - (2019)
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of connective tissue diseases, collectively known as myositis. Diagnosis of IIM is challenging while timely recognition of an IIM is of utter importance considering treatment options
Externí odkaz:
https://doaj.org/article/dabafd0c5c7c403fbf151134a65df4d0
Autor:
Diane van der Woude, René E.M. Toes, John B. Haanen, Tom W.J. Huizinga, Jaap A. Bakker, Annette Grummels, Els M.E. Verdegaal, Ellen H. Kapiteijn, Elisa A. Rozeman, Emma C. de Moel
Immune-checkpoint inhibitors (ICIs) activate the immune system to assault cancer cells in a manner that is not antigen specific. We hypothesized that tolerance may also be broken to autoantigens, resulting in autoantibody formation, which could be as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2dfd65fb79cf617d2789e87015744582
https://doi.org/10.1158/2326-6066.c.6548081
https://doi.org/10.1158/2326-6066.c.6548081
Autor:
Diane van der Woude, René E.M. Toes, John B. Haanen, Tom W.J. Huizinga, Jaap A. Bakker, Annette Grummels, Els M.E. Verdegaal, Ellen H. Kapiteijn, Elisa A. Rozeman, Emma C. de Moel
Supplementary Figure S1 Supplementary Figure S2 Supplementary Table S1 Supplementary Table S2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e03577eb135aaf4696279f9855c88f11
https://doi.org/10.1158/2326-6066.22536224.v1
https://doi.org/10.1158/2326-6066.22536224.v1
Autor:
Jonathan W. Uzorka, Lucia J.M. Kroft, Jaap A. Bakker, Erik W. van Zwet, Erik Huisman, Corine Prins, Cornelis J. van der Zwan, Tom H.M. Ottenhoff, Sandra M. Arend
Publikováno v:
Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, Vol 15, Iss , Pp - (2019)
Background: Several radiological features have been reported in association with latent tuberculosis infection (LTBI) but it has not been studied which are specific. The aim of this study was to evaluate allegedly characteristic abnormalities on ches
Externí odkaz:
https://doaj.org/article/22b75d04dfe947259a781e3846385bb3
Autor:
Nienke M. van de Velde, Zaïda Koeks, Mirko Signorelli, Nisha Verwey, Maurice Overzier, Jaap A. Bakker, Gautam Sajeev, James Signorovitch, Valeria Ricotti, Jan Verschuuren, Kristy Brown, Pietro Spitali, Erik H. Niks
Publikováno v:
Neurology, 100(9), E975-E984. LIPPINCOTT WILLIAMS & WILKINS
Neurology
Neurology
Background and ObjectivesThe slow and variable disease progression of Becker muscular dystrophy (BMD) urges the development of biomarkers to facilitate clinical trials. We explored changes in 3 muscle-enriched biomarkers in serum of patients with BMD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a57db93bedb6271d9c761dcf773bd2
https://hdl.handle.net/1887/3590525
https://hdl.handle.net/1887/3590525
Autor:
N Chantal Peltenburg, Jörgen Bierau, Jaap A Bakker, Jolanda A Schippers, Selwyn H Lowe, Aimée D C Paulussen, Bianca J C van den Bosch, Mathie P G Leers, Bettina E Hansen, Annelies Verbon
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0191069 (2018)
The purine analogues tenofovir and abacavir are precursors of potential substrates for the enzyme Inosine 5'-triphosphate pyrophosphohydrolase (ITPase). Here, we investigated the association of ITPase activity and ITPA genotype with the occurrence of
Externí odkaz:
https://doaj.org/article/830f603febab47ee816ac4e1156ed1d3
Autor:
Michèle J. C. de Kok, Rob C. I. Wüst, Alexander F. Schaapherder, Jan H.N. Lindeman, Jaap A. Bakker, Melissa C. Zuiderwijk, Sylvia E. Le Dévédec
Publikováno v:
de Kok, M J C, Schaapherder, A F, Wüst, R C I, Zuiderwijk, M, Bakker, J A, Lindeman, J H N & Le Dévédec, S E 2021, ' Circumventing the Crabtree effect in cell culture : A systematic review ', Mitochondrion, vol. 59, pp. 83-95 . https://doi.org/10.1016/j.mito.2021.03.014
Mitochondrion, 59, 83-95. ELSEVIER SCI LTD
Mitochondrion, 59, 83-95. Elsevier BV
Mitochondrion, 59, 83-95. ELSEVIER SCI LTD
Mitochondrion, 59, 83-95. Elsevier BV
Metabolic reprogramming and mitochondrial dysfunction are central elements in a broad variety of physiological and pathological processes. While cell culture established itself as a versatile technique for the elaboration of physiology and disease, s
Autor:
Adrienne Elisabeth van der Hoeven, Kevin van Waaij, Denise Bijlenga, Frederik Willem Cornelis Roelandse, Sebastiaan Overeem, Jaap Adriaan Bakker, Rolf Fronczek, Gert Jan Lammers
Publikováno v:
Sleep, 45(7):zsac103. American Academy of Sleep Medicine
SLEEP, 45(7), 1-8. OXFORD UNIV PRESS INC
SLEEP, 45(7), 1-8. OXFORD UNIV PRESS INC
Study Objectives The most sensitive and specific investigative method for the diagnosis of narcolepsy type 1 (NT1) is the determination of hypocretin-1 (orexin-A) deficiency (≤110 pg/mL) in cerebrospinal fluid using a radioimmunoassay (RIA). We aim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bef946ceb733fffa6b0e7b427bf580
https://research.tue.nl/nl/publications/2e7b6004-f3fd-4eae-aa19-58d9a7374e76
https://research.tue.nl/nl/publications/2e7b6004-f3fd-4eae-aa19-58d9a7374e76
Autor:
Rob M. Moonen, Maurice J. Huizing, Giacomo Cavallaro, Gema E. González-Luis, Pilar Bas-Suárez, Jaap A. Bakker, Eduardo Villamor
Publikováno v:
International Journal of Molecular Sciences, Vol 16, Iss 1, Pp 19-39 (2014)
Endogenously produced inhibitors of nitric oxide (NO) synthase, in particular asymmetric dimethylarginine (ADMA), are currently considered of importance in various disease states characterized by reduced NO availability. We investigated the associati
Externí odkaz:
https://doaj.org/article/5ad814695ffb44e09221c472b60da418