Zobrazeno 1 - 10
of 571
pro vyhledávání: '"Jaap, Goudsmit"'
Autor:
Anna L. Beukenhorst, Jacopo Frallicciardi, Keira L. Rice, Martin H. Koldijk, Joana C. Moreira de Mello, Jaco M. Klap, Christoforos Hadjichrysanthou, Clarissa M. Koch, Kelly A. S. da Costa, Nigel Temperton, Babette A. de Jong, Helene Vietsch, Bertjan Ziere, Boris Julg, Wouter Koudstaal, Jaap Goudsmit
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Avian A(H5N1) influenza virus poses an elevated zoonotic threat to humans, and no pharmacological products are currently registered for fast-acting pre-exposure protection in case of spillover leading to a pandemic. Here, we show that an epi
Externí odkaz:
https://doaj.org/article/b85d0a98851e4b6a93bc94df6dc119e5
Autor:
Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela Phillips, Michael M. Desai, Kanin Wichapong, Gerry A. F. Nicolaes, Wouter Koudstaal, Galit Alter, Jaap Goudsmit
Publikováno v:
Frontiers in Virology, Vol 3 (2023)
Externí odkaz:
https://doaj.org/article/9503b87ece3445a8a8e5186347752be5
Autor:
Anna L. Beukenhorst, Jacopo Frallicciardi, Clarissa M. Koch, Jaco M. Klap, Angela Phillips, Michael M. Desai, Kanin Wichapong, Gerry A. F. Nicolaes, Wouter Koudstaal, Galit Alter, Jaap Goudsmit
Publikováno v:
Frontiers in Virology, Vol 2 (2022)
Human monoclonal antibodies (hmAbs) that protect against all influenza A and B strains are considered the road to universal influenza vaccines. Based on publicly-available data, we analyze the mechanistic and structural basis of pan-influenza protect
Externí odkaz:
https://doaj.org/article/7caffad1dc504f2b98bbea4798b7eb24
Autor:
Julia W. Wu, Amber Yaqub, Yuan Ma, Wouter Koudstaal, Albert Hofman, M. Arfan Ikram, Mohsen Ghanbari, Jaap Goudsmit
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Application of biological age as a measure of an individual´s health status offers new perspectives into extension of both lifespan and healthspan. While algorithms predicting mortality and most aging-related morbidities have been reported,
Externí odkaz:
https://doaj.org/article/8a4784fa5b184545b3e5fc85ad14cfce
Autor:
Caroline Atyeo, Matthew D. Slein, Stephanie Fischinger, John Burke, Alexandra Schäfer, Sarah R. Leist, Natalia A. Kuzmina, Chad Mire, Anna Honko, Rebecca Johnson, Nadia Storm, Matthew Bernett, Pei Tong, Teng Zuo, Junrui Lin, Adam Zuiani, Caitlyn Linde, Todd Suscovich, Duane R. Wesemann, Anthony Griffiths, John R. Desjarlais, Boris D. Juelg, Jaap Goudsmit, Alexander Bukreyev, Ralph Baric, Galit Alter
Publikováno v:
JCI Insight, Vol 6, Iss 1 (2021)
The rapid spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), coupled with a lack of therapeutics, has paralyzed the globe. Although significant effort has been invested in identifying antibodies that block infection, the ability
Externí odkaz:
https://doaj.org/article/d178291b87fe4f6cbc744ca06c3cb4dc
Autor:
Anna L. Beukenhorst, Clarissa M. Koch, Christoforos Hadjichrysanthou, Galit Alter, Frank de Wolf, Roy M. Anderson, Jaap Goudsmit
Publikováno v:
European Journal of Epidemiology. 38:237-242
Neither vaccination nor natural infection result in long-lasting protection against SARS-COV-2 infection and transmission, but both reduce the risk of severe COVID-19. To generate insights into optimal vaccination strategies for prevention of severe
Autor:
Adrian Apetri, Rosa Crespo, Jarek Juraszek, Gabriel Pascual, Roosmarijn Janson, Xueyong Zhu, Heng Zhang, Elissa Keogh, Trevin Holland, Jay Wadia, Hanneke Verveen, Berdien Siregar, Michael Mrosek, Renske Taggenbrock, Jeroenvan Ameijde, Hanna Inganäs, Margot van Winsen, Martin H. Koldijk, David Zuijdgeest, Marianne Borgers, Koen Dockx, Esther J. M. Stoop, Wenli Yu, Els C. Brinkman-van der Linden, Kimberley Ummenthum, Kristof van Kolen, Marc Mercken, Stefan Steinbacher, Donata de Marco, Jeroen J. Hoozemans, Ian A. Wilson, Wouter Koudstaal, Jaap Goudsmit
Publikováno v:
Acta Neuropathologica Communications, Vol 6, Iss 1, Pp 1-17 (2018)
Abstract Misfolding and aggregation of tau protein are closely associated with the onset and progression of Alzheimer’s Disease (AD). By interrogating IgG+ memory B cells from asymptomatic donors with tau peptides, we have identified two somaticall
Externí odkaz:
https://doaj.org/article/c0395ac19eb24ba4951a4cf53142723b
Autor:
Christoforos Hadjichrysanthou, Anna L. Beukenhorst, Clarissa M. Koch, Galit Alter, Jaap Goudsmit, Roy M. Anderson, Frank de Wolf
Publikováno v:
Infectious Diseases and Therapy. 11:2287-2296
Autor:
Joan E. M. van der Lubbe, Jessica Vreugdenhil, Sarra Damman, Joost Vaneman, Jaco Klap, Jaap Goudsmit, Katarina Radošević, Ramon Roozendaal
Publikováno v:
Virology Journal, Vol 14, Iss 1, Pp 1-12 (2017)
Abstract Background Various studies have shown that infants under the age of 6 months are especially vulnerable for complications due to influenza. Currently there are no vaccines licensed for use in this age group. Vaccination of pregnant women duri
Externí odkaz:
https://doaj.org/article/eca3622f79424008814481b2c9992526
Autor:
M. Arfan Ikram, Brad Manor, Jaap Goudsmit, Julia W Wu, Francesco U.S. Mattace-Raso, M. Kamran Ikram, Berend E. Westerhof, Maryam Kavousi, Frank J. Wolters, Albert Hofman, Lewis A. Lipsitz, Junhong Zhou, Yuan Ma
Publikováno v:
Alzheimers Dement
Alzheimer's and Dementia, 17(7), 1134-1144. Elsevier Inc.
Alzheimer's and Dementia, 17(7), 1134-1144. Elsevier Inc.
Introduction: We hypothesized that subclinical disruption in blood pressure (BP) dynamics, captured by lower complexity and higher variability, may contribute to dementia risk, above and beyond BP levels. Methods: This prospective cohort study follow