Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jaana Nopola-Hemmi"'
Autor:
Katariina Hannula-Jouppi, Nina Kaminen-Ahola, Mikko Taipale, Ranja Eklund, Jaana Nopola-Hemmi, Helena Kääriäinen, Juha Kere
Publikováno v:
PLoS Genetics, Vol 1, Iss 4, p e50 (2005)
Dyslexia, or specific reading disability, is the most common learning disorder with a complex, partially genetic basis, but its biochemical mechanisms remain poorly understood. A locus on Chromosome 3, DYX5, has been linked to dyslexia in one large f
Externí odkaz:
https://doaj.org/article/2c1a54394a7f4878a992e6b27a8615f6
Autor:
Katri Kantojärvi, Eira Leinonen, Hans Matsson, Jetro J. Tuulari, Harri Merisaari, Myriam Peyrard-Janvid, Torkel Klingberg, Elisabet Einarsdottir, Juha Kere, Antti-Jussi Ämmälä, Jani Saunavaara, Linnea Karlsson, Nancy Yiu-Lin Yu, Hasse Karlsson, Riitta Parkkola, Tiina Paunio, Jaana Nopola-Hemmi, Fahimeh Darki, Noora M. Scheinin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
A whole-genome linkage analysis in a Finnish pedigree of eight cases with developmental dyslexia (DD) revealed several regions shared by the affected individuals. Analysis of coding variants from two affected individuals identified rs146011974G > A (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3337a76ce6664cb676818afeb313f29e
https://pubmed.ncbi.nlm.nih.gov/28839234
https://pubmed.ncbi.nlm.nih.gov/28839234
Autor:
Isabel Tapia-Páez, J. Bruce Tomblin, Marco Zucchelli, Sudha K. Iyengar, Johannes Schumacher, Shelley D. Smith, Jaana Nopola-Hemmi, Markus M. Nöthen, Xiaotang Fan, Barbara A. Lewis, Jason Spencer, Bruce F. Pennington, Jeffrey W. Gilger, Per Hoffmann, Heidi Anthoni, Gerd Schulte-Körne, Catherine M. Stein, Davor Stanic, Sari Mäkelä, Marie-Estelle Hokkanen, Richard K. Olson, Evan R. Simpson, Mikko Taipale, George W. Hynd, Jan-Åke Gustafsson, Juha Kere, Heikki Lyytinen, Myriam Peyrard-Janvid, Wah Chin Boon, Bertram Müller-Myhsok, Eero Castrén, Jacqueline Schoumans, Magnus Nordenskjöld, Paavo H.T. Leppänen, Lara Sucheston
Publikováno v:
Behavior Genetics
Inspired by the localization, on 15q21.2 of the CYP19A1 gene in the linkage region of speech and language disorders, and a rare translocation in a dyslexic individual that was brought to our attention, we conducted a series of studies on the properti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e7501c876a2d734b004d808f916133
https://doi.org/10.1007/s10519-012-9532-3
https://doi.org/10.1007/s10519-012-9532-3
Autor:
Johannes Schumacher, Jaana Nopola-Hemmi, Päivi Onkamo, Heidi Anthoni, Andreas Warnke, Heikki Lyytinen, Markus M. Nöthen, Myriam Peyrard-Janvid, Kristiina Tammimies, Juha Kere, Hans Matsson, Nina Neuhoff, Paavo H.T. Leppänen, G. Schulte-Körne, Marco Zucchelli
Publikováno v:
Behavior Genetics. 41:134-140
Four genes, DYX1C1, ROBO1, DCDC2 and KIAA0319 have been studied both genetically and functionally as candidate genes for developmental dyslexia, a common learning disability in children. The identification of novel genes is crucial to better understa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abb249cbd97a8bec6d8f886ca6ed5ff5
https://doi.org/10.1007/s10519-010-9431-4
https://doi.org/10.1007/s10519-010-9431-4
Autor:
Birgitta Myllyluoma, Katariina Hannula-Jouppi, Juha Kere, Nina Kaminen, Heikki Lyytinen, Päivi Lahermo, Arja Voutilainen, Jaana Nopola-Hemmi, Marjo Kestilä, Kurt Müller, M Kaaranen
Publikováno v:
University of Helsinki
Developmental dyslexia is a distinct learning disability with unexpected difficulty in learning to read despite adequate intelligence, education, and environment, and normal senses. The genetic aetiology of dyslexia is heterogeneous and loci on chrom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2227a06385abc1425c20d35e21f2a3e3
https://doi.org/10.1136/jmg.40.5.340
https://doi.org/10.1136/jmg.40.5.340
Autor:
Tuomas Haltia, Jaana Nopola-Hemmi, Arja Voutilainen, Mikko Taipale, Juha Kere, Anna-Elina Lehesjoki
Publikováno v:
Journal of Medical Genetics. 37:771-775
Developmental dyslexia is characterised by difficulties in learning to read. As reading is a complex cognitive process, multiple genes are expected to contribute to the pathogenesis of dyslexia. The genetics of dyslexia has been a target of molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fb2bc1fe9d231ba2d068396015f02f0
https://doi.org/10.1136/jmg.37.10.771
https://doi.org/10.1136/jmg.37.10.771
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 32(3)
In rodents, theRobo1gene regulates midline crossing of major nerve tracts, a fundamental property of the mammalian CNS. However, the neurodevelopmental function of the humanROBO1gene remains unknown, apart from a suggested role in dyslexia. We theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7c1b9e57a851eb2b6495dc7cf8ce3c5
https://pubmed.ncbi.nlm.nih.gov/22262894
https://pubmed.ncbi.nlm.nih.gov/22262894
Autor:
Päivi Onkamo, Marco Zucchelli, Heide Griesemann, Jaana Nopola-Hemmi, Bertram Müller-Myhsok, Per Hoffmann, Heidi Anthoni, Ingegerd Fransson, Hans Matsson, Juha Kere, Myriam Peyrard-Janvid, Markus M. Nöthen, Andreas Warnke, Heikki Lyytinen, Gerd Schulte-Körne, Johannes Schumacher, Satu Massinen
Publikováno v:
Human molecular genetics. 16(6)
DYX3, a locus for dyslexia, resides on chromosome 2p11-p15. We have refined its location on 2p12 to a 157 kb region in two rounds of linkage disequilibrium (LD) mapping in a set of Finnish families. The observed association was replicated in an indep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a060813fe53e75d7aa9406864109d7d0
https://pubmed.ncbi.nlm.nih.gov/17309879
https://pubmed.ncbi.nlm.nih.gov/17309879
Autor:
Jaana Nopola-Hemmi, Mikael Huss, Heikki Lyytinen, Markus M. Nöthen, Hans Matsson, Elisabet Einarsdottir, Andreas Warnke, Myriam Peyrard-Janvid, Paavo H.T. Leppänen, Juha Kere, G. Schulte-Körne, Nina Neuhoff, Helena Persson, Johannes Schumacher, Ettore Tiraboschi
Publikováno v:
Journal of Human Genetics
Genetic studies of complex traits have become increasingly successful as progress is made in next-generation sequencing. We aimed at discovering single nucleotide variation present in known and new candidate genes for developmental dyslexia: CYP19A1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d63aa661dc28a7f4129cdecb94ef2fb3
http://juuli.fi/Record/0009305615
http://juuli.fi/Record/0009305615
Autor:
Päivi Lahermo, Päivi Onkamo, Katariina Hannula-Jouppi, Heikki Lyytinen, Marco Zucchelli, Juha Kere, Nina Kaminen, Jaana Nopola-Hemmi, Myriam Peyrard-Janvid, Heidi Anthoni, Arja Voutilainen
Publikováno v:
Human genetics. 114(5)
Developmental dyslexia, or reading disability, is a multigenic complex disease for which at least five loci, i.e. DYX1-3 and DYX5-6, have been clearly identified from the human genome. To date, DYX1C1 is the only dyslexia candidate gene cloned. We ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f32a24bf9779b07ac6fe02c4e1bbd36
https://pubmed.ncbi.nlm.nih.gov/15007729
https://pubmed.ncbi.nlm.nih.gov/15007729