Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jaana Künnapuu"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Vascular endothelial growth factor-C (VEGF-C) stimulates lymphatic vessel growth in transgenic models, via viral gene delivery, and as a recombinant protein. Expressing eukaryotic proteins like VEGF-C in bacterial cells has limitations, as t
Externí odkaz:
https://doaj.org/article/f05cb0c5dd694be79f821f86e2dfa56f
Publikováno v:
Biology, Vol 10, Iss 2, p 167 (2021)
Specific proteolytic cleavages turn on, modify, or turn off the activity of vascular endothelial growth factors (VEGFs). Proteolysis is most prominent among the lymphangiogenic VEGF-C and VEGF-D, which are synthesized as precursors that need to und
Externí odkaz:
https://doaj.org/article/5b1fc0e69bca4a0dbb1eed41752180d2
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 13545, p 13545 (2021)
In this focused review, we address the role of the kallikrein-related peptidase 3 (KLK3), also known as prostate-specific antigen (PSA), in the regulation of angiogenesis. Early studies suggest that KLK3 is able to inhibit angiogenic processes, which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::4c482c4c33c9583d6930b3348e890916
https://www.mdpi.com/1422-0067/22/24/13545
https://www.mdpi.com/1422-0067/22/24/13545
Autor:
Jaana Künnapuu, Michael Jeltsch
Publikováno v:
Sci Signal
Exogenous administration of lymphangiogenic growth factors is widely used to study changes in lymphatic function in pathophysiology. However, this approach can result in off-target effects, thereby generating conflicting data. To circumvent this issu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e920e551e4ace6785de59446f2de512
https://doi.org/10.1126/scisignal.abj5058
https://doi.org/10.1126/scisignal.abj5058
Specific proteolytic cleavages turn on, modify, or turn off the activity of vascular endothelial growth factors (VEGFs). Proteolysis is most prominent among the lymphangiogenic VEGF-C and VEGF-D, which are synthesized as precursors that need to und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2fc083f009c8543e81891167e28493b6
Autor:
Petra M. Tauscher, Minh Nguyen, Jaana Künnapuu, Ari Löytynoja, Kavita Arora, Osamu Shimmi, Nina Tiusanen
Publikováno v:
Developmental Biology. 389(2):149-159
Dorsoventral patterning of the Drosophila embryo is regulated by graded distribution of bone morphogenetic proteins (BMPs) composed of two ligands, decapentaplegic (Dpp) a BMP2/4 ortholog and screw (Scw) a BMP5/6/7/8 family member. scwE1 encodes an u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79679487bae3f632919e8ce131b8749a
Publikováno v:
Insect Biochemistry and Molecular Biology. 43:466-473
The pattern of wing venation varies considerably among different groups of insects and has been used as a means of species-specific identification. However, little is known about how wing venation is established and diversified among insects. The dec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c90e296563772f88751adcb89b5baab
https://doi.org/10.1016/j.ibmb.2013.02.008
https://doi.org/10.1016/j.ibmb.2013.02.008
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 106(21)
Maturation of bone morphogenetic proteins (BMPs) requires cleavage of their precursor proteins by furin-type proprotein convertases. Here, we find that cleavage sites of the BMP2/4/decapentaplegic (DPP) subfamily have been evolutionary diversified an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ffc653dda3544a1b4c266ae962758f8
https://pubmed.ncbi.nlm.nih.gov/19433798
https://pubmed.ncbi.nlm.nih.gov/19433798
Autor:
Sanna Vuorikoski, Jaana Künnapuu, Katri Pajusola, Jarkko Soronen, Teresa Pereira, Helder André, Seppo Ylä-Herttuala, Petra Korpisalo, Kari Alitalo, Lorenz Poellinger
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 19(10)
Therapeutic angiogenesis provides a potential alternative for the treatment of cardiovascular ischemic diseases. Vascular endothelial growth factor (VEGF) is an important component of the angiogenic response to ischemia. Here we used adeno-associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ea09f909ccde2d72f420da658b3db88
https://pubmed.ncbi.nlm.nih.gov/15958522
https://pubmed.ncbi.nlm.nih.gov/15958522
Autor:
Jaana Künnapuu, Osamu Shimmi
Publikováno v:
ResearcherID
Decapentaplegic (DPP) and bone morphogenetic protein (BMP)-2 and -4 type ligands form a branch of the transforming growth factor-beta (TGFbeta) superfamily. They play prominent roles in metazoan developmental processes as diverse as cell proliferatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a00a52946b86b4da0a24dbfa07518a75
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000275820100004&KeyUID=WOS:000275820100004
http://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=ORCID&SrcApp=OrcidOrg&DestLinkType=FullRecord&DestApp=WOS_CPL&KeyUT=WOS:000275820100004&KeyUID=WOS:000275820100004