Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jaana, Niittymäki"'
Publikováno v:
APMIS. 114:539-548
L-fucose is a fundamental monosaccharide component of many mammalian glycoproteins and glycolipids. Fucosylation requires GDP-L-fucose as a donor of fucose and a specific fucosyltransferase (Fuc-T) to catalyze the transfer of L-fucose to various lact
Publikováno v:
APMIS. 113:613-620
The sialyl Lewis x (NeuAcalpha2-3Galbeta1-4(Fucalpha1-3)GlcNAc) determinants serve as ligands in the selectin-mediated adhesion of leukocytes to activated endothelium. The final step in the sialyl Lewis x synthesis is catalyzed by alpha1-3-fucosyltra
Publikováno v:
Glycobiology. 14:1285-1294
The de novo synthesis and expression of sulfo sLex glycan on vascular endothelial glycoproteins has a central role in the initiation of inflammatory reactions, serving as a putative ZIP code for organ-specific trafficking of leukocytes into sites of
Autor:
Risto Renkonen, Pirkko Mattila, Solveig Sjöblom, Jaana Niittymäki, Christophe Roos, Laura Huopaniemi
Publikováno v:
European Journal of Biochemistry. 271:78-86
In the salvage pathway of GDP-l-fucose, free cytosolic fucose is phosphorylated by l-fucokinase to form l-fucose-1-phosphate, which is then further converted to GDP-l-fucose in the reaction catalyzed by GDP-l-fucose pyrophosphorylase. We report here
Autor:
Laura Hirvas, Jaana Niittymäki, Heidi Salminen, Risto Renkonen, Hanna Salo, Ossi Renkonen, Pirkko Mattila, Ritva Niemelä, Minoru Fukuda
Publikováno v:
Journal of Biological Chemistry. 273:27633-27639
In the present experiments the cDNA coding for a truncated form of the beta1,6N-acetylglucosaminyltransferase responsible for the conversion of linear to branched polylactosamines in human PA1 cells was expressed in Sf9 insect cells. The catalytic ec
Autor:
Jaana Niittymäki, Jarkko Räbinä, Sanna Toppila, Timo Paavonen, Pirkko Mattila, Risto Renkonen, Jutta Renkonen, Marja-Leena Majuri, Ossi Renkonen, Juha Pekka Turunen, Laura Hirvas
Publikováno v:
Glycoconjugate Journal. 14:593-600
Extravasation from the blood of malignant tumour cells that form metastasis and leukocytes that go into tissues require contact between selectins and their sialyl Lewis x and sialyl Lewis a (sLe(x) and sLe(a) respectively) decorated ligands. Endothel
Autor:
Jaana, Niittymäki, Pirkko, Mattila, Christophe, Roos, Laura, Huopaniemi, Solveig, Sjöblom, Risto, Renkonen
Publikováno v:
European journal of biochemistry. 271(1)
In the salvage pathway of GDP-L-fucose, free cytosolic fucose is phosphorylated by L-fucokinase to form L-fucose-L-phosphate, which is then further converted to GDP-L-fucose in the reaction catalyzed by GDP-L-fucose pyrophosphorylase. We report here
Autor:
Masayuki Miyasaka, Jaana Niittymäki, Marja-Leena Majuri, Risto Renkonen, Pirkko Mattila, Einari Aavik, Jarkko Räbinä, Ossi Renkonen, Sinikka Tiisala
Publikováno v:
FEBS letters. 455(1-2)
L-selectin guides lymphocytes into peripheral lym- phoid tissues by recognizing glycoprotein ligands decorated with 6-sulfated sialyl Lewis x (sulfo sLex). Here we have used a rat peripheral lymph node high endothelial cell line (Ax) to study in deta