Výsledky vyhledávání - "Jaakko L. Pohjoismäki"

Akademický článek

TFAM knockdown-triggered mtDNA-nucleoid aggregation and a decrease in mtDNA copy number induce the reorganization of nucleoid populations and mitochondria-associated ER-membrane contacts

Autor: Koit Aasumets, Yuliya Basikhina, Jaakko L. Pohjoismäki, Steffi Goffart, Joachim Gerhold

Publikováno v: Biochemistry and Biophysics Reports, Vol 28, Iss , Pp 101142- (2021)

The correct organization of mitochondrial DNA (mtDNA) in nucleoids and the contacts of mitochondria with the ER play an important role in maintaining the mitochondrial genome distribution within the cell. Mitochondria-associated ER membranes (MAMs) c

Externí odkaz: https://doaj.org/article/39426409ccb144888c9438378921349f

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Top3α is the replicative topoisomerase in mitochondrial DNA replication

Autor: Anu, Hangas, Nina J, Kekäläinen, Alisa, Potter, Craig, Michell, Kauko J, Aho, Chiara, Rutanen, Johannes N, Spelbrink, Jaakko L, Pohjoismäki, Steffi, Goffart

Publikováno v: Nucleic acids research. 50(15)

Mitochondrial DNA has been investigated for nearly fifty years, but many aspects of the maintenance of this essential small genome remain unknown. Like any genome, mammalian mitochondrial DNA requires the function of topoisomerases to counter and reg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::4ab9eadd4e943c6391ac625923ba156f
https://pubmed.ncbi.nlm.nih.gov/35904803

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