Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Ja Yil Lee"'
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Advances in single-molecule techniques have uncovered numerous biological secrets that cannot be disclosed by traditional methods. Among a variety of single-molecule methods, single-molecule fluorescence imaging techniques enable real-time visualizat
Externí odkaz:
https://doaj.org/article/05cf658c86364e86ab90d42df886756e
Autor:
Wooyoung Kang, Kook Sun Ha, Heesoo Uhm, Kyuhyong Park, Ja Yil Lee, Sungchul Hohng, Changwon Kang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Bacterial transcription is terminated when RNA polymerases encounter terminator sequences. Using a single-molecule fluorescence assay, here the authors show that the release of transcript RNA precedes RNA polymerase dissociation and that the remainin
Externí odkaz:
https://doaj.org/article/d97e30411e7f425eab5086b9c09f7d1c
Autor:
Carol Cho, Juwon Jang, Yujin Kang, Hiroki Watanabe, Takayuki Uchihashi, Seung Joong Kim, Koichi Kato, Ja Yil Lee, Ji-Joon Song
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
ATAD2 AAA+ ATPases are a family of histone chaperones that regulate nucleosome density and chromatin dynamics. Here, authors find that the fission yeast ATAD2 homolog Abo1 deposits histone H3–H4 onto DNA in an ATP-hydrolysis-dependent manner, and p
Externí odkaz:
https://doaj.org/article/566979fd3d954b63b376d18804509722
Autor:
Hee Jin Chung, Joo Rak Lee, Tae Moon Kim, Soomi Kim, Kibeom Park, Myung-Jin Kim, Eunyoung Jung, Subin Kim, Eun A Lee, Jae Sun Ra, Sunyoung Hwang, Ja Yil Lee, Orlando D Schärer, Yonghwan Kim, Kyungjae Myung, Hongtae Kim
Publikováno v:
Nucleic Acids Research. 51:631-649
TRAIP is a key factor involved in the DNA damage response (DDR), homologous recombination (HR) and DNA interstrand crosslink (ICL) repair. However, the exact functions of TRAIP in these processes in mammalian cells are not fully understood. Here we i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8920f21b8e5baa69624b2f6b7cadbcbd
https://doi.org/10.1093/nar/gkac1226
https://doi.org/10.1093/nar/gkac1226
Autor:
Jung-Min Oh, Yujin Kang, Jumi Park, Yubin Sung, Dayoung Kim, Yuri Seo, Eun A Lee, Jae Sun Ra, Enkhzul Amarsanaa, Young-Un Park, Seon Young Lee, Jung Me Hwang, Hongtae Kim, Orlando Schärer, Seung Woo Cho, Changwook Lee, Kei-ichi Takata, Ja Yil Lee, Kyungjae Myung
Publikováno v:
Nucleic Acids Research.
DNA double-strand break (DSB) repair via homologous recombination is initiated by end resection. The extent of DNA end resection determines the choice of the DSB repair pathway. Nucleases for end resection have been extensively studied. However, it i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e4872204eb805556eb09dc000ad1582
https://doi.org/10.1093/nar/gkad308
https://doi.org/10.1093/nar/gkad308
Autor:
Na Young, Cheon, Ja Yil, Lee
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2528
R-loops are nucleic acid structures containing a DNA-RNA hybrid and the associated non-template single-stranded DNA. R-loops are not only involved in many biological processes but also cause genomic instability when they are abnormally regulated. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1e73f2d3e5bdb02cb20a531bd7061611
https://pubmed.ncbi.nlm.nih.gov/35704196
https://pubmed.ncbi.nlm.nih.gov/35704196
Publikováno v:
Molecules and Cells. 44:79-87
Chromatin dynamics is essential for maintaining genomic integrity and regulating gene expression. Conserved bromodomain-containing AAA+ ATPases play important roles in nucleosome organization as histone chaperones. Recently, the high-resolution cryo-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba7b25fefafa516231a27d44bad537e3
https://doi.org/10.14348/molcells.2021.2242
https://doi.org/10.14348/molcells.2021.2242
Autor:
Ja Yil Lee, Jongjin Cha
Publikováno v:
Journal of the Korean Physical Society. 78:442-448
Single-molecule (SM) techniques have been contributing to unraveling the detailed mechanisms underlying DNA metabolic processes with superior spatiotemporal resolution beyond the limit of traditional biochemical assays. However, SM techniques need to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4c207a46b09a76d233da342b52e5ea5
https://doi.org/10.1007/s40042-020-00031-9
https://doi.org/10.1007/s40042-020-00031-9
Autor:
Min Kyung Ju, Joo Rak Lee, Yeonsong Choi, Seon Young Park, Hee Jung Sul, Hee Jin Chung, Soyeong An, Semin Lee, Eunyoung Jung, Bohyun Kim, Bo Youn Choi, Bum Jun Kim, Hyeong Su Kim, Hyun Lim, Ho Suk Kang, Jae Seung Soh, Kyungjae Myung, Kab Choong Kim, Ji Woong Cho, Jinwon Seo, Tae Moon Kim, Ja Yil Lee, Yonghwan Kim, Hongtae Kim, Dae Young Zang
Publikováno v:
EMBO Rep
Genome instability is one of the leading causes of gastric cancers. However, the mutational landscape of driver genes in gastric cancer is poorly understood. Here, we investigate somatic mutations in 25 Korean gastric adenocarcinoma patients using wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cdc26bd858d2a745546d47b8a72ee93
https://doi.org/10.15252/embr.202153492
https://doi.org/10.15252/embr.202153492
Publikováno v:
Journal of Visualized Experiments.
Chromatin is a higher-order structure that packages eukaryotic DNA. Chromatin undergoes dynamic alterations according to the cell cycle phase and in response to environmental stimuli. These changes are essential for genomic integrity, epigenetic regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11bef16cbee95259a03b3196425a6a42
https://doi.org/10.3791/63501
https://doi.org/10.3791/63501