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pro vyhledávání: '"Ja A. Mefford"'
Autor:
Andrej Sali, Sj J. Johns, Js S. Witte, Te E. Ferrin, Doug Stryke, Rl L. Davis, Sw W. Yee, Avner Schlessinger, Ah H. Ramirez, Ra A. Castro, Km M. Morrissey, Pui-Yan Kwok, Km M. Giacomini, Dm M. Roden, Gh H. Jang, Ca A. McCarty, Se E. Hesselson, G. Jenkins, Jh H. Choi, Ra A. Wilke, Pj J. Joski, Ja A. Mefford
Publikováno v:
Clinical Pharmacology & Therapeutics. 90:674-684
Multidrug and toxin extrusion 2 (MATE2-K (SLC47A2)), a polyspecific organic cation exporter, facilitates the renal elimination of the antidiabetes drug metformin. In this study, we characterized genetic variants of MATE2-K, determined their associati