Protease-activated kinase II as the potential mediator of insulin-stimulated phosphorylation of ribosomal protein S6

Autor: Olga Perisic, Ja, Traugh

Publikováno v: Europe PubMed Central

One of the earliest responses to insulin in target cells is stimulation of the phosphorylation of ribosomal protein S6. When exponentially growing 3T3-L1 cells are serum-starved, little phosphorylation of S6 is observed; however, following addition o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::37e1506a589e1eba363c28008b2484ac
https://pubmed.ncbi.nlm.nih.gov/6350281

Protease-activated kinase II mediates multiple phosphorylation of ribosomal protein S6 in reticulocytes

Autor: Olga Perisic, Ja, Traugh

Publikováno v: Europe PubMed Central

Ribosomal protein S6 was phosphorylated in vitro by the cAMP-independent protein kinase, protease-activated kinase II. The enzyme incorporated up to four phosphates into S6 as shown by analysis of the phosphorylated derivatives by two-dimensional gel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::e9b6b12e1141b7c5f1b97708aa1620e1
http://europepmc.org/abstract/med/6643463

PAK2 activated by Cdc42 and caspase 3 mediates different cellular responses to oxidative stress-induced apoptosis.

Autor: Huang J; Department of Biochemistry, University of California, Riverside, CA 92521, United States of America., Huang A; Canyon Crest Academy, San Diego, CA 92130, United States of America., Poplawski A; Geisinger Commonwealth School of Medicine, Scranton, PA 18509, United States of America; Misericordia University, Dallas, PA 18612, United States of America., DiPino F Jr; Misericordia University, Dallas, PA 18612, United States of America., Traugh JA; Department of Biochemistry, University of California, Riverside, CA 92521, United States of America., Ling J; California University of Science and Medicine, Colton, CA 92324, United States of America; Geisinger Commonwealth School of Medicine, Scranton, PA 18509, United States of America; Department of Biochemistry, University of California, Riverside, CA 92521, United States of America. Electronic address: lingj@cusm.org.

Publikováno v: Biochimica et biophysica acta. Molecular cell research [Biochim Biophys Acta Mol Cell Res] 2020 Apr; Vol. 1867 (4), pp. 118645. Date of Electronic Publication: 2020 Jan 08.

Amide hydrogen/deuterium exchange & MALDI-TOF mass spectrometry analysis of Pak2 activation.

Autor: Hsu YH; Department of Chemistry, Tunghai University. howardhsu@thu.edu.tw, Traugh JA

Publikováno v: Journal of visualized experiments : JoVE [J Vis Exp] 2011 Nov 26 (57), pp. e3602. Date of Electronic Publication: 2011 Nov 26.

Analysis of conformational changes during activation of protein kinase Pak2 by amide hydrogen/deuterium exchange.

Autor: Hsu YH; Department of Biochemistry and Division of Biomedical Sciences, University of California, Riverside, California 92521, USA., Johnson DA, Traugh JA

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2008 Dec 26; Vol. 283 (52), pp. 36397-405. Date of Electronic Publication: 2008 Nov 04.