Zobrazeno 1 - 10
of 813
pro vyhledávání: '"Ja, Hartley"'
Autor:
Hui, Rong1 (AUTHOR) huirong850623@163.com, Tan, Huijuan1 (AUTHOR)
Publikováno v:
BMC Microbiology. 11/15/2024, Vol. 24 Issue 1, p1-14. 14p.
Autor:
D. S. Bose, Melissa Smellie, JA Hartley, David E. Thurston, Andrew S. Thompson, Terence C. Jenkins
Publikováno v:
Biochemistry. 42:8232-8239
Members of a homologous series of pyrrolo[2,1-c][1,4]benzodiazepine (PBD) dimers with C8-O-(CH(2))(n)-O-C8' diether linkages (n = 3-6 for 2a-d, respectively) have been studied for their ability to interact with oligonucleotide duplexes containing pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0b1674c1d625e0fe00ab349ea244b95
https://doi.org/10.1021/bi034313t
https://doi.org/10.1021/bi034313t
Autor:
Hesse, Daryl R.1 drhesse@ku.edu, Fite, Paula J.1
Publikováno v:
Journal of Child & Family Studies. Sep2024, Vol. 33 Issue 9, p2992-3003. 12p.
Publikováno v:
British Journal of Cancer
The DNA damage and the sequence specificity of guanine-N7 alkylation produced by the novel, positively charged, antineoplastic agent 1,4-bis(2'-chloroethyl)-1,4-diazabicyclo-[2.2.1] heptane dimaleate (Dabis maleate) and its uncharged tertiary amine a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51e72433bc8e34868912fab3ae8670ff
https://doi.org/10.1038/bjc.1990.53
https://doi.org/10.1038/bjc.1990.53
Publikováno v:
Journal of medicinal chemistry. 47(19)
Neocarzinostatin (NCS) is an antitumor antibiotic comprising a 1:1 protein-chromophore complex and exhibits cytotoxic action through DNA cleavage via H-abstraction. Cytotoxic activity resides with the chromophore 1 alone, while the protein (apoNCS) p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8893ad13a75e263c13e696e3ed8afa68
https://pubmed.ncbi.nlm.nih.gov/15341486
https://pubmed.ncbi.nlm.nih.gov/15341486
Autor:
Nd, Henderson, Sm, Lacy, Hare Cc, O., Ja, Hartley, Siobhán McClean, Lp, Wakelin, Lr, Kelland, Dj, Robins
Publikováno v:
Europe PubMed Central
The aim of this work was to develop new bifunctional alkylating agents which damage DNA in a selective manner. In order to extend our previously published work on conformationally restricted nitrogen mustards containing one piperidine ring, new bispi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::904ba457ec36ad6c6952407c84e018e9
https://pubmed.ncbi.nlm.nih.gov/9807160
https://pubmed.ncbi.nlm.nih.gov/9807160
Autor:
Zhou, Chengcheng1 (AUTHOR), Bo, Wenhao1 (AUTHOR), El-Kassaby, Yousry A.2 (AUTHOR), Li, Wei1 (AUTHOR) bjfuliwei@bjfu.edu.cn
Publikováno v:
BMC Plant Biology. 4/26/2024, Vol. 24 Issue 1, p1-14. 14p.
Autor:
Foudil, Samy-Adrien1,2 (AUTHOR) samyfoudil@gmail.com, Macaluso, Emiliano1,2 (AUTHOR)
Publikováno v:
Scientific Reports. 4/4/2024, Vol. 14 Issue 1, p1-16. 16p.
Autor:
Ae, Semper, Ja, Hartley, Jm, Tunon-De-Lara, Peter Bradding, Ae, Redington, Mk, Church, St, Holgate
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c1c82e7b252f9e7732400b05a7ce5717
https://pubmed.ncbi.nlm.nih.gov/8526038
https://pubmed.ncbi.nlm.nih.gov/8526038
Autor:
Tc, Fisher, Ae, Milner, Cd, Gregory, Al, Jackman, Gw, Aherne, Ja, Hartley, Caroline Dive, Ja, Hickman
Publikováno v:
Europe PubMed Central
The hypothesis was tested that expression of bcl-2 could provide protection against apoptosis induced by cytotoxic drugs via a mechanism which was different from the classical determinants of drug resistance. Sensitivity and resistance to inhibitors
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::daa014cdf0b2251aeff12d38212c2d57
https://pubmed.ncbi.nlm.nih.gov/8324744
https://pubmed.ncbi.nlm.nih.gov/8324744