Zobrazeno 1 - 10
of 695
pro vyhledávání: '"Ja, Hamilton"'
Publikováno v:
Blood. 86:2948-2956
Colony-stimulating factor 1 (CSF-1) causes the activation of STAT1 and STAT3 transcription factors in bone marrow macrophages (BMM), in the macrophage cell line BAC1.2F5, and in fibroblasts that express the wild-type receptor for CSF-1. Fibroblasts e
Publikováno v:
Europe PubMed Central
TGF-beta increased in a dose-dependent manner the production of plasminogen activator inhibitor-1 (PAI-1) in cultured human synovial fibroblast-like cells, as measured by ELISA. Significant increases in PAI-1 were first detected in cell supernatants
Publikováno v:
Blood. 80:2805-2810
Vascular smooth muscle cells (SMC) are a major cell type comprising the walls of blood vessels. We report the synthesis of granulocyte colony- stimulating factor (G-CSF) by cultured human SMC obtained from the internal mammary artery and thoracic aor
Autor:
JA Hamilton
Publikováno v:
Physiology. 7:264-270
13C-nuclear magnetic resonance spectroscopy provides structural and dynamic details of lipid-protein interactions in complexes of fatty acids and serum albumin. With native fatty acids as nonperturbing probes, this determines microscopic properties o
Publikováno v:
Blood. 77:841-848
Granulocyte-macrophage colony-stimulating factor (GM-CSF) raised the plasminogen activator (PA) activity of cultured human monocytes. This activity was characterized to be urokinase-PA (u-PA) by incubation with specific IgG and by sodium dodecyl sulf
Publikováno v:
Europe PubMed Central
Purified hematopoietic growth factors such as colony-stimulating factor- 1 (CSF-1) or macrophage CSF, granulocyte-macrophage CSF, and interleukin-3 or multi-CSF, stimulate the urokinase-type plasminogen activator (u-PA) activity of murine bone marrow
Autor:
Pk, Vadiveloo, Gino Vairo, Novak U, Ak, Royston, Whitty G, El, Filonzi, Ej, Cragoe, Ja, Hamilton
Publikováno v:
Europe PubMed Central
There is currently much interest in the mechanisms of action of antiproliferative agents and their effects on cell cycle machinery. In the present study we examined the mechanisms of action of four unrelated agents known to inhibit proliferation of C
Publikováno v:
Blood. 80(1)
Using a specific enzyme-linked immunosorbent assay, plasminogen activator inhibitor-2 (PAI-2) was quantitated in cultures of human monocytes. Lipopolysaccharide (LPS) increased both extracellular and cell-associated PAI-2 levels, as well as PAI-2 mRN
Publikováno v:
Europe PubMed Central
Some of the important controlling events regulating eukaryotic S-phase progression are considered to occur late in the G1 stage of the cell cycle. We show here that stimulation of DNA synthesis in bone marrow-derived macrophages (BMM) by macrophage C
Autor:
DL Cheung, JA Hamilton
Publikováno v:
Blood. 79(8)
It is reported in this study that a subpopulation of highly purified human peripheral blood human monocytes can proliferate in response to colony-stimulating factor-1 (CSF-1), granulocyte-macrophage colony- stimulating factor (GM-CSF), and interleuki