Zobrazeno 1 - 10
of 150
pro vyhledávání: '"Ja, Bluestone"'
Autor:
Dm, Smith, Ja, Bluestone, Dr, Jeyarajah, Mh, Newberg, Victor Engelhard, Jr, Thistlethwaite, Es, Woodle
Publikováno v:
Europe PubMed Central
A long term goal of investigators working in our laboratory has been to develop new mAbs for use as immunosuppressive agents. As a means toward achieving this goal, several new mAbs (hybridomas) have been developed by screening fusions for supernatan
Autor:
M. K., Mili1, Talukdar, Sharmistha2, Sarmah, Monikuntal3, Saikia, Asha4 ashasaikia23.as@gmail.com
Publikováno v:
Asian Journal of Medical Sciences. Aug2023, Vol. 14 Issue 8, p113-116. 4p.
Autor:
Walunas TL, Lenschow DJ, Bakker CY, Linsley PS, Freeman GJ, Green JM, Thompson CB, Bluestone JA
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2011 Oct 01; Vol. 187 (7), pp. 3466-74.
Autor:
Dm, Pardoll, Bj, Fowlkes, Andrew Lew, Wl, Maloy, Ma, Weston, Ja, Bluestone, Rh, Schwartz, Je, Coligan, Am, Kruisbeek
Publikováno v:
Europe PubMed Central
To elucidate the developmental pathways of T cells that bear TCR gamma delta, we have analyzed the kinetics of expression and biochemical characteristics of gamma delta receptors in the thymus and spleen of normal and athymic (nude) mice, as well as
Autor:
Dm, Pardoll, Andrew Lew, Wl, Maloy, Bj, Fowlkes, Kruisbeek A, Ja, Bluestone, Rh, Schwartz, Je, Coligan
Publikováno v:
Europe PubMed Central
While much is known about the structure and function of the T-cell receptor (TCR) alpha beta heterodimer, information has just begun to emerge about the gamma protein, the product of a third rearranging T-cell receptor gene. We describe the use of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c88096b12c093cea2827b75c120aadf7
http://europepmc.org/abstract/med/3453602
http://europepmc.org/abstract/med/3453602
Autor:
Wm, Kast, Ja, Bluestone, Mh, Heemskerk, Joke Spaargaren, Ac, Voordouw, Jd, Ellenhorn, Cj, Melief
Publikováno v:
Europe PubMed Central
C57BL/6 mice are protected from a lethal pneumonia caused by Sendai virus when treated with low doses of mAb directed to the CD3 Ag. The protective mechanism is not due to an accelerated Sendai virus-specific Th cell, CTL, or antibody response but to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::04488171c0c271968fdec5decd9ba420
http://europepmc.org/abstract/med/2168920
http://europepmc.org/abstract/med/2168920
Publikováno v:
Europe PubMed Central
The present studies have made use of in vitro derived H-2Kb mutants to analyze the fine specificity of alloreactive cytotoxic T lymphocytes (CTL). The variants were derived by negatively selecting mutagenized tumor cells with a monoclonal anti-H-2Kb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2efbe6d20ec2bfdd42a79c54cf496328
http://europepmc.org/abstract/med/2426358
http://europepmc.org/abstract/med/2426358
Publikováno v:
Europe PubMed Central
A mAb directed against the CD3 molecule was used to identify a subset of CD3+, CD4-, CD8- T cells previously undefined in the peripheral lymphoid organs of the mouse. Biochemical analysis of CD3+, CD4-, CD8- splenocytes revealed that the vast majorit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::87c1151f05e24c18d3a02409652a5387
http://europepmc.org/abstract/med/3260917
http://europepmc.org/abstract/med/3260917
Autor:
Benoit Salomon, Ja, Bluestone
Publikováno v:
Europe PubMed Central
The role of CD28/B7 and LFA-1/ICAM costimulation in proliferation and Th1/Th2 differentiation of naive CD4+ T cells was addressed using T cells from DO11.10 TCR transgenic mice stimulated by dendritic cells. The blockade of either CD28/B7 or LFA-1/IC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::465fcad39612b269f6d379a4ec564c8f
http://europepmc.org/abstract/med/9820482
http://europepmc.org/abstract/med/9820482
Publikováno v:
Europe PubMed Central
This study examined long-term phenotypic and functional effects of TCR ligation in vivo. Flow cytometric analysis of T cells from mice treated with anti-CD3 revealed an increase in CD44 expression in both the CD4+ and CD8+ populations. The phenotypic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9e2d78a17a5607b3e7cda4622fc54396
http://europepmc.org/abstract/med/7543536
http://europepmc.org/abstract/med/7543536