Výsledky vyhledávání - "Ja, Berzofsky"

In vitro restoration of T cell immune function in human immunodeficiency virus-positive persons: effects of interleukin (IL)-12 and anti-IL-10

Autor: Al, Landay, Mario Clerici, Hashemi F, Kessler H, Ja, Berzofsky, Gm, Shearer

Publikováno v: Europe PubMed Central

Cells from human immunodeficiency virus (HIV)-positive patients were evaluated for their in vitro responsiveness to recall antigen, alloantigen, and phytohemagglutinin (PHA) following the in vitro addition of interleukin (IL)-12 or anti-IL-10. Three-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ecf54c0ca434d3c4ec684845888824c8
https://pubmed.ncbi.nlm.nih.gov/8627058

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Human immunodeficiency virus type 1 (HIV-1)-seronegative injection drug users at risk for HIV exposure have antibodies to HLA class I antigens and T cells specific for HIV envelope

Autor: Beretta A, Sh, Weiss, Rappocciolo G, Mayur R, De Santis C, Quirinale J, Antonio Cosma, Robbioni P, Gm, Shearer, Ja, Berzofsky

Publikováno v: Europe PubMed Central

The question of whether persistently seronegative persons at high risk for human immunodeficiency virus type 1 (HIV-1) infection exhibit HIV-1-specific T cell responses and antibodies to HIV-1 envelope epitopes shared with selected HLAs was assessed.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::088367658d758caa158d77bfffb8f51d
https://pubmed.ncbi.nlm.nih.gov/8699088

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Human T cell recognition of polymorphic epitopes from malaria circumsporozoite protein

Autor: Annie De Groot, Ah, Johnson, Wl, Maloy, Ia, Quakyi, Em, Riley, Menon A, Sm, Banks, Ja, Berzofsky, Mf, Good

Publikováno v: Europe PubMed Central

Lymphocytes obtained from forty individuals living in a malaria endemic area of West Africa were tested for in vitro proliferative responses to peptides representing variant regions of the immunodominant T cell domain of the circumsporozoite protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::59c6781e046a1da51fd2013a88e2573c
https://pubmed.ncbi.nlm.nih.gov/2469729

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IL-1 is an autocrine growth factor for T cell clones

Autor: Tartakovsky B, Finnegan A, Muegge K, Dt, Brody, Ej, Kovacs, Smith MR, Ja, Berzofsky, Ha, Young, scott durum

Publikováno v: Europe PubMed Central

Activation of Th lymphocytes requires that Ag be presented on the surface of accessory cells displaying Ia Ag. A number of studies have concluded that the T cell also requires IL-1 from accessory cells. However, we recently reported that one murine T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ba9f0224dce84deba1785d30afa8171c
https://pubmed.ncbi.nlm.nih.gov/2972778

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Exposure to human immunodeficiency virus (HIV) type I indicated by HIV-specific T helper cell responses before detection of infection by polymerase chain reaction and serum antibodies [corrected]

Autor: Mario Clerici, Ja, Berzofsky, Gm, Shearer, Co, Tacket

Publikováno v: Europe PubMed Central

A healthy individual at risk for human immunodeficiency virus type 1 (HIV-1) infection was studied longitudinally for 19 months for evidence of exposure to and infection with HIV. Peripheral blood mononuclear cells (PBMC) were tested at 1, 5, 13, 16,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::931930fed6e526ae970d091f55200285
http://europepmc.org/abstract/med/1829105

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Production of T-T hybrids from T cell clones. Direct comparison between cloned T cells and T hybridoma cells derived from them

Autor: Ozaki S, scott durum, Muegge K, York-Jolley J, Ja, Berzofsky

Publikováno v: Europe PubMed Central

It has been assumed, without direct evidence, that T cell hybridomas and non-transformed T cell clones are both good models of normal Ag-specific T cells. To compare directly the difference in activation of cloned normal T cells and T hybridoma cells

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afbcaa4a6fba51cb2655b0a688391897
http://europepmc.org/abstract/med/2454265

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CTL responses of HLA-A2.1-transgenic mice specific for hepatitis C viral peptides predict epitopes for CTL of humans carrying HLA-A2.1

Autor: Shirai M, Arichi T, Nishioka M, Nomura T, Ikeda K, Kawanishi K, Victor Engelhard, Sm, Feinstone, Ja, Berzofsky

Publikováno v: Europe PubMed Central

Vaccine development in animal models depends on ability to recognize epitopes seen by human T cells. In this work, we show that CTL responses in transgenic mice expressing human HLA-A2.1 prospectively predict the same four of 11 hepatitis C virus (HC

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3effad2fae2a3a57f9b7f2e1f4f94289
http://europepmc.org/abstract/med/7533182

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Immunogenicity and immunopathogenicity of an autoimmune epitope are potentiated by increasing MHC binding through residue substitution

Autor: At, Kozhich, Rachel Caspi, Ja, Berzofsky, Gery I

Publikováno v: Europe PubMed Central

We have previously shown that in Lewis rats, peptide 273-283 (TWEGSGVLPCV) of rat interphotoreceptor retinoid-binding protein (IRBP) serves as a "surrogate" epitope for pathogenic lymphocytes sensitized against peptide 1181-1191 (SWEGVGVVPDV) of bovi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5479f4ec61b8c9809a19387cbfb50990
http://europepmc.org/abstract/med/9126974

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