Zobrazeno 1 - 10
of 353
pro vyhledávání: '"JW, Holloway"'
Autor:
R Granell, JA Curtin, S Haider, N Kitaba, S Mathie, L Gregory, LL Yates, M Tutino, J Hankinson, M Perretti, JM Vonk, SH Arshad, P Cullinan, S Fontanella, G Roberts, GH Koppelman, A Simpson, S Turner, CS Murray, CM Lloyd, JW Holloway, A Custovic
BackgroundMany genes associated with asthma explain only a fraction of its heritability. Most genome-wide association studies (GWASs) used a broad definition of “doctor-diagnosed asthma”, thereby diluting genetic signals by not considering asthma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a855eb5151b767ef965668e9af73baa
https://doi.org/10.1101/2023.03.03.23284449
https://doi.org/10.1101/2023.03.03.23284449
Autor:
E, Repapi, I, Sayers, LV, Wain, RB, Burton, T, Johnson, M, Obeidat, JH, Zhao, A, Ramasamy, G, Zhai, V, Vitart, JE, Huffman, W, Igl, E, Albrecht, P, Deloukas, J, Henderson, J, Granell, WL, McArdle, AR, Rudnicka, Consortium, Wellcome Trust Case Control, I, Barroso, RJF, Loos, NJ, Wareham, L, Mustelin, Rantanen, Taina, I, Surakka, M, Imboden, HE, Wichmann, I, Grkovic, S, Jankovic, L, Zgaga, A, Hartikainen, L, Peltonen, U, Gyllensten, Å, Johansson, G, Zaboli, H, Campbell, SH, Wild, JF, Wilson, S, Gläser, G, Homuth, H, Völzke, M, Mangino, N, Soranzo, TD, Spector, O, Polašek, I, Rudan, AF, Wright, M, Heliövaara, S, Ripatti, A, Pouta, Å, Torinsson Naluai, A, Olin, K, Torén, MN, Cooper, AL, James, LJ, Palmer, AD, Hingorani, SG, Wannamethee, PH, Whincup, GD, Smith, S, Ebrahim, TM, McKeever, ID, Pavord, AK, MacLeod, AD, Morris, DJ, Porteous, C, Cooper, E, Dennison, S, Shaheen, S, Karrasch, E, Schnabel, H, Schulz, H, Grallert, N, Bouatia-Naji, J, Delplanque, P, Froguel, JD, Blakey, Team, The NSHD Respiratory Study, JR, Britton, RW, Morris, JW, Holloway, DA, Lawlor, J, Hui, F, Nyberg, M, Jarvelin, C, Jackson, M, Kähönen, J, Kaprio, NM, Probst-Hensch, B, Koch, C, Hayward, DE, Evans, P, Elliott, DP, Strachan, IP, Hall, MD, Tobin
Pulmonary function measures are heritable traits that predict morbidity and mortality and define chronic obstructive pulmonary disease (COPD). We tested genome-wide association with forced expiratory volume in 1 s (FEV1) and the ratio of FEV1 to forc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1222::aefe3de804274fbd8ed1dba5a61e3a7f
http://urn.fi/URN:NBN:fi:jyu-201909184206
http://urn.fi/URN:NBN:fi:jyu-201909184206
Autor:
Rj, Valk, Kreiner-Møller E, Mn, Kooijman, Guxens M, Stergiakouli E, Sääf A, Jp, Bradfield, Geller F, Mg, Hayes, Dl, Cousminer, Körner A, Thiering E, Ja, Curtin, Myhre R, Huikari V, Joro R, Kerkhof M, Nm, Warrington, Pitkänen N, Ntalla I, Horikoshi M, Veijola R, Rm, Freathy, Yy, Teo, Sj, Barton, Dm, Evans, Jp, Kemp, St Pourcain B, Sm, Ring, Gd, Smith, Bergström A, Kull I, Hakonarson H, Fd, Mentch, Bisgaard H, Chawes B, Stokholm J, Waage J, Eriksen P, Sevelsted A, Melbye M, Cm, Duijn, Medina-Gomez C, Hofman A, Jc, Jongste, Hr, Taal, Ag, Uitterlinden, Ll, Armstrong, Eriksson J, Palotie A, Bustamante M, Estivill X, Jr, Gonzalez, Llop S, Kiess W, Mahajan A, Flexeder C, Cm, Tiesler, Cs, Murray, Simpson A, Magnus P, Sengpiel V, Al, Hartikainen, Keinanen-Kiukaanniemi S, Lewin A, Da Silva Couto Alves A, Ai, Blakemore, Jl, Buxton, Kaakinen M, Rodriguez A, Sebert S, Vaarasmaki M, Lakka T, Lindi V, Gehring U, Ds, Postma, Ang W, Jp, Newnham, Lp, Lyytikäinen, Pahkala K, Ot, Raitakari, Panoutsopoulou K, Zeggini E, Di, Boomsma, Groen-Blokhuis M, Ilonen J, Franke L, Jn, Hirschhorn, Th, Pers, Liang L, Huang J, Hocher B, Knip M, Sm, Saw, Jw, Holloway, Melén E, Sf, Grant, Feenstra B, Wl, Lowe, Widén E, Sergeyev E, Grallert H, Adnan Custovic, Jacobsson B, Jarvelin MR, Atalay M, Gh, Koppelman, Ce, Pennell, Niinikoski H, Gv, Dedoussis, Mi, Mccarthy, Tm, Frayling, Sunyer J, Nj, Timpson, Rivadeneira F, Bønnelykke K, Vw, Jaddoe
Publikováno v:
Europe PubMed Central
van der Valk, R J P, Kreiner-Moller, E, Kooijman, M N, Guxens, M, Stergiakouli, E, Saaf, A, Bradfield, J P, Geller, F, Hayes, M G, Cousminer, D L, Koerner, A, Thiering, E, Curtin, J A, Myhre, R, Huikari, V, Joro, R, Kerkhof, M, Warrington, N M, Pitkanen, N, Ntalla, I, Horikoshi, M, Veijola, R, Freathy, R M, Teo, Y, Barton, S J, Evans, D M, Kemp, J P, St Pourcain, B, Ring, S M, Smith, G D, Bergstrom, A, Kull, I, Hakonarson, H, Mentch, F D, Bisgaard, H, Chawes, B, Stokholm, J, Waage, J, Eriksen, P, Sevelsted, A, Melbye, M, van Duijn, C M, Medina-Gomez, C, Hofman, A, de Jongste, J C, Taal, H R, Uitterlinden, A G, Armstrong, L L, Eriksson, J, Palotie, A, Bustamante, M, Estivill, X, Gonzalez, J R, Llop, S, Kiess, W, Mahajan, A, Flexeder, C, Tiesler, C M T, Murray, C S, Simpson, A, Magnus, P, Sengpiel, V, Hartikainen, A, Keinanen-Kiukaanniemi, S, Lewin, A, Alves, A D S C, Blakemore, A I, Buxton, J L, Kaakinen, M, Rodriguez, A, Sebert, S, Vaarasmaki, M, Lakka, T, Lindi, V, Gehring, U, Postma, D S, Ang, W, Newnham, J P, Lyytikainen, L, Pahkala, K, Raitakari, O T, Panoutsopoulou, K, Zeggini, E, Boomsma, D I, Groen-Blokhuis, M M, Ilonen, J, Franke, L, Hirschhorn, J N, Pers, T H, Liang, L, Huang, J, Hocher, B, Knip, M, Saw, S, Holloway, J W, Melen, E, Grant, S F A, Feenstra, B, Lowe, W L, Widen, E, Sergeyev, E, Grallert, H, Custovic, A, Jacobsson, B, Jarvelin, M, Atalay, M, Koppelman, G H, Pennell, C E, Niinikoski, H, Dedoussis, G V, McCarthy, M I, Frayling, T M, Sunyer, J, Timpson, N J, Rivadeneira, F, Bonnelykke, K & Jaddoe, V W V 2015, ' A novel common variant in DCST2 is associated with length in early life and height in adulthood ', Human Molecular Genetics, vol. 24, no. 4, pp. 1155-1168 . https://doi.org/10.1093/hmg/ddu510
Hum. Mol. Genet. 24, 1155-1168 (2015)
Human Molecular Genetics
Human Molecular Genetics, 24(4), 1155-1168. Oxford University Press
van der Valk, R J P, Kreiner-Moller, E, Kooijman, M N, Guxens, M, Stergiakouli, E, Saaf, A, Bradfield, J P, Geller, F, Hayes, M G, Cousminer, D L, Koerner, A, Thiering, E, Curtin, J A, Myhre, R, Huikari, V, Joro, R, Kerkhof, M, Warrington, N M, Pitkanen, N, Ntalla, I, Horikoshi, M, Veijola, R, Freathy, R M, Teo, Y, Barton, S J, Evans, D M, Kemp, J P, St Pourcain, B, Ring, S M, Smith, G D, Bergstrom, A, Kull, I, Hakonarson, H, Mentch, F D, Bisgaard, H, Chawes, B, Stokholm, J, Waage, J, Eriksen, P, Sevelsted, A, Melbye, M, van Duijn, C M, Medina-Gomez, C, Hofman, A, de Jongste, J C, Taal, H R, Uitterlinden, A G, Armstrong, L L, Eriksson, J, Palotie, A, Bustamante, M, Estivill, X, Gonzalez, J R, Llop, S, Kiess, W, Mahajan, A, Flexeder, C, Tiesler, C M T, Murray, C S, Simpson, A, Magnus, P, Sengpiel, V, Hartikainen, A, Keinanen-Kiukaanniemi, S, Lewin, A, Alves, A D S C, Blakemore, A I, Buxton, J L, Kaakinen, M, Rodriguez, A, Sebert, S, Vaarasmaki, M, Lakka, T, Lindi, V, Gehring, U, Postma, D S, Ang, W, Newnham, J P, Lyytikainen, L, Pahkala, K, Raitakari, O T, Panoutsopoulou, K, Zeggini, E, Boomsma, D I, Groen-Blokhuis, M M, Ilonen, J, Franke, L, Hirschhorn, J N, Pers, T H, Liang, L, Huang, J, Hocher, B, Knip, M, Saw, S, Holloway, J W, Melen, E, Grant, S F A, Feenstra, B, Lowe, W L, Widen, E, Sergeyev, E, Grallert, H, Custovic, A, Jacobsson, B, Jarvelin, M, Atalay, M, Koppelman, G H, Pennell, C E, Niinikoski, H, Dedoussis, G V, McCarthy, M I, Frayling, T M, Sunyer, J, Timpson, N J, Rivadeneira, F, Bonnelykke, K & Jaddoe, V W V 2015, ' A novel common variant in DCST2 is associated with length in early life and height in adulthood ', Human Molecular Genetics, vol. 24, no. 4, pp. 1155-1168 . https://doi.org/10.1093/hmg/ddu510
Hum. Mol. Genet. 24, 1155-1168 (2015)
Human Molecular Genetics
Human Molecular Genetics, 24(4), 1155-1168. Oxford University Press
Common genetic variants have been identified for adult height, but not much is known about the genetics of skeletal growth in early life. To identify common genetic variants that influence fetal skeletal growth, we meta-analyzed 22 genome-wide associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::a16d83a298e23e3af7006697fd3c8c53
http://europepmc.org/abstract/med/25281659
http://europepmc.org/abstract/med/25281659
Autor:
Lyle John Palmer, Kc, Barnes, Pr, Burton, Chen H, Wo, Cookson, Collaborative Study on the Genetics of Asthma, Ka, Deichmann, Rc, Elston, Jw, Holloway, Kb, Jacobs, Laitinen T, Wjst M
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1491ccb1c323772f0b6f212f7e9c780d
http://europepmc.org/abstract/med/21523954
http://europepmc.org/abstract/med/21523954
Autor:
Nwokoro C, Pandya H, Turner S, Sandra Eldridge, Cj, Griffiths, Vulliamy T, Price D, Sanak M, Jw, Holloway, Brugha R, Koh L, Dickson I, Rutterford C, Grigg J
Publikováno v:
Europe PubMed Central
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::1a6cae0388c815a088a1799349433643
http://europepmc.org/abstract/med/26632627
http://europepmc.org/abstract/med/26632627
Publikováno v:
Europe PubMed Central
Spirometry is used worldwide to diagnose respiratory disease, and it is a validated measure to assess airway obstruction. Irreversible airway obstruction is the defining feature of chronic obstructive pulmonary disease (COPD). Thus, an FEV(1)/FVC rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::685f4aaebc2af894307f713b4ff9da5d
http://europepmc.org/abstract/med/21873323
http://europepmc.org/abstract/med/21873323
Autor:
Cm, Lindgren, Im, Heid, Jc, Randall, Lamina C, Steinthorsdottir V, Qi L, Ek, Speliotes, Thorleifsson G, Cj, Willer, Bm, Herrera, Au, Jackson, Lim N, Scheet P, Soranzo N, Amin N, Ys, Aulchenko, Jc, Chambers, Drong A, Luan J, Hn, Lyon, Rivadeneira F, Sanna S, Nj, Timpson, Mc, Zillikens, Jh, Zhao, Almgren P, Bandinelli S, Aj, Bennett, Rn, Bergman, Ll, Bonnycastle, Sj, Bumpstead, Sj, Chanock, Cherkas L, Chines P, Coin L, Cooper C, Crawford G, Doering A, Dominiczak A, Asf, Doney, Ebrahim S, Elliott P, Erdos MR, Estrada K, Ferrucci L, Fischer G, Ng, Forouhi, Gieger C, Grallert H, Cj, Groves, Grundy S, Guiducci C, Hadley D, Hamsten A, As, Havulinna, Hofman A, Holle R, Jw, Holloway, Illig T, Isomaa B, Lc, Jacobs, Jameson K, Jousilahti P, Karpe F, Kuusisto J, Laitinen J, Gm, Lathrop, Da, Lawlor, Mangino M, Wl, Mcardle, Meitinger T, Ma, Morken, Ap, Morris, Munroe P, Narisu N, Nordström A, Nordström P, Ba, Oostra, Cna, Palmer, Payne F, Jf, Peden, Inga Prokopenko, Renström F, Ruokonen A, Salomaa V, Ms, Sandhu, Lj, Scott, Scuteri A, Silander K, Song K, Yuan X, Hm, Stringham, Aj, Swift, Tuomi T, Uda M, Vollenweider P, Waeber G, Wallace C, Gb, Walters, Mn, Weedon, Jcm, Witteman, Zhang C, Zhang W, Mj, Caulfield, Fs, Collins, Davey Smith G, Inm, Day, Pw, Franks, At, Hattersley, Fb, Hu, Jarvelin M, Kong A, Js, Kooner, Laakso M, Lakatta E, Mooser V, Ad, Morris, Peltonen L, Nj, Samani, Td, Spector, Dp, Strachan, Tanaka T, Tuomilehto J, Ag, Uitterlinden, Cm, Duijn, Nj, Wareham, Procardis, Watkins For The Consortia H., Dm, Waterworth, Boehnke M, Deloukas P, Groop L, Dj, Hunter, Thorsteinsdottir U, Schlessinger D, H-, Wichmann, Tm, Frayling, Gr, Abecasis, Jn, Hirschhorn, Rjf, Loos, Stefansson K, Kl, Mohlke, Barroso I, Giant Mi, Mccarthy For The Consortium
Publikováno v:
Europe PubMed Central
PLoS Genetics
PLoS Genetics, Vol 5, Iss 7 (2009)
PLoS Genetics
PLoS Genetics, Vol 5, Iss 7 (2009)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc4aa71e313de404e331242e6d0f0e4f
http://europepmc.org/abstract/PMC/PMC2722420
http://europepmc.org/abstract/PMC/PMC2722420
Autor:
Jiang Y; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA. yjiang4@memphis.edu., Zhang H; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA., Chen S; Department of Mathematical Science, University of Nebraska Medical Center, Omaha, NE, USA.; Department of Biostatistics, University of Nebraska Medical Center, Omaha, NE, USA., Ewart S; Department of Large Animal Clinical Sciences, Michigan State University, East Lansing, MI, USA., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Arshad H; Clinical and Experimental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK., Karmaus W; Division of Epidemiology, Biostatistics, and Environmental Health, School of Public Health, University of Memphis, Memphis, TN, USA. karmaus1@memphis.edu.
Publikováno v:
Scientific reports [Sci Rep] 2024 Aug 27; Vol. 14 (1), pp. 19812. Date of Electronic Publication: 2024 Aug 27.
Autor:
Wai HA; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Svobodova E; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Department of Experimental Biology, Faculty of Science, Masaryk University, Brno, Czech Republic.; Department of Clinical Immunology and Allergology, Faculty of Medicine, Masaryk University, Brno, Czech Republic., Herrera NR; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Douglas AGL; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Oxford Centre for Genomic Medicine, Oxford University Hospitals NHS Foundation Trust, Oxford, UK., Holloway JW; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK., Baralle FE; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; Fondazione Fegato, Area Science Park Basovizza, 34149, Trieste, Italy., Baralle M; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK.; International Centre for Genetic Engineering and Biotechnology (ICGEB), Padriciano 99, 34149, Trieste, Italy., Baralle D; Human Development and Health, Faculty of Medicine, University of Southampton, Southampton, UK. d.baralle@soton.ac.uk.
Publikováno v:
Experimental & molecular medicine [Exp Mol Med] 2024 Aug; Vol. 56 (8), pp. 1816-1825. Date of Electronic Publication: 2024 Aug 01.