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of 207
pro vyhledávání: '"JUPITER trial"'
Akademický článek
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Publikováno v:
Diabetes. 70
Background: Statins increase T2D risk despite favorable effects on lipids, inflammation, and cardiovascular disease (CVD). Statins may modulate associations of T2D-related BCAAs with incident T2D. Methods: JUPITER (NCT00239681) randomized rosuvastati
Autor:
Andrew Fleck, Peter Hoang, Grace Knuttinen, Rahmi Oklu, Hassan Albadawi, Sailendra Naidu, Alex Wallace
Publikováno v:
Cardiovascular Diagnosis and Therapy. 7:S207-S218
The anti-inflammatory effects of statins have likely not been used to their fullest extent, particularly in reducing venous thromboembolic events. Current therapy for thrombotic events hinges on anticoagulation via heparin, warfarin or new oral antic
Autor:
Til Stürmer, Jin Liern Hong, Sara E. Dempster, Iksha Herr, Stephen R. Cole, Michael Webster-Clark, Michele Jonsson Funk, Robert J. LoCasale
Our study explored the application of methods to generalize randomized controlled trial results to a target population without individual-level data. We compared 4 methods using aggregate data for the target population to generalize results from the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07d696fb5051ea0d6516f1eee5e71d30
Autor:
Akihiro Hirakawa, Manabu Muto, Toshio Kubo, Hisahiro Matsubara, Yukiko Mori, Yasushi Shimizu, Hirotoshi Akita, Sadakatsu Ikeda, Eri Ishibashi, Ryo Kudo, Hiroshi Nishihara, Satoshi Miyake, Yohei Harada, Chikashi Ishioka, Naoko Sueoka-Aragane, Hidekazu Shirota, Masayuki Kano, Ukihide Tateishi, Shinichi Toyooka, Hideyuki Hayashi
Publikováno v:
Journal of Clinical Oncology. 39:TPS3141-TPS3141
TPS3141 Background: The human epidermal growth factor receptor 2 (HER2) gene amplification and mutations have emerged as oncogenic drivers and therapeutic targets not limited to breast and gastric cancers, but also in a variety of cancers. However, e
Autor:
Samia Mora, Paul M. Ridker, Jay Wohlgemuth, Robert J. Glynn, Charles M. Rowland, Zhihong Chen, H.Robert Superko, Michael P. Caulfield, Ronald M. Krauss
Publikováno v:
Circulation. 132:2220-2229
Background— Cardiovascular disease (CVD) can occur in individuals with low low-density lipoprotein (LDL) cholesterol (LDL-C). We investigated whether detailed measures of LDL subfractions and other lipoproteins can be used to assess CVD risk in a p
Publikováno v:
Journal of the American College of Cardiology. 72(3)
Background Although lipoprotein(a) [Lp(a)] is associated with incident cardiovascular disease (CVD), its contribution to prediction remains controversial. Objectives This study examined the association and clinical utility of Lp(a) with incident CVD
Autor:
Daniel I. Chasman, Patrick R. Lawler, Akintunde O. Akinkuolie, Svati H. Shah, Robert J. Glynn, Audrey Y. Chu, Paul M. Ridker, Latha Padmanabhan, Samia Mora, William E. Kraus, Damian M. Craig
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Levels of LDL (low‐density lipoprotein) cholesterol in the population are declining, and increasing attention is being focused on residual lipid‐related pathways of atherosclerotic cardiovascular disease risk beyond LDL cholesterol. Am
Autor:
Joseph B. Muhlestein, Paul M. Ridker, Benjamin D. Horne, Nina P. Paynter, Jeffrey L. Anderson
Publikováno v:
European Journal of Preventive Cardiology. 22:519-526
Previously, we showed that sex-specific complete blood count (CBC) risk scores strongly predicted risk of all-cause mortality in multiple sets of general medical patients. This study evaluated the CBC risk score in an independent, well-studied intern
Autor:
Caspar Matzhold, Michael Leutner, Peter Klimek, Stefan Thurner, Jürgen Harreiter, Carola Deischinger, Alexandra Kautzky-Willer, Luise Bellach
Publikováno v:
Annals of the Rheumatic Diseases. 80:e181-e181
We read with interest the correspondence of Lai .1 Whether statin therapy impacts the risk of osteoporosis is still a matter of debate. We have recently shown that there is a dose-dependent relationship between statins and diagnosis of osteoporosis;