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Clinical Management of Argentine Hemorrhagic Fever using Ribavirin and Favipiravir, Belgium, 2020

Publikováno v: Emerging Infectious Diseases, Vol 26, Iss 7, Pp 1562-1566 (2020)
Emerging infectious diseases
Emerging Infectious Diseases
Emerging Infectious Diseases, Centers for Disease Control and Prevention, In press, 26 (7), pp.1562-1566. ⟨10.3201/eid2607.200275⟩
Emerging infectious diseases, 26 (7

We report a case of Argentine hemorrhagic fever diagnosed in a woman in Belgium who traveled from a disease-endemic area. Patient management included supportive care and combination therapy with ribavirin and favipiravir. Of 137 potential contacts, i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91bac55becf7b8c484615ee454e10a33
https://wwwnc.cdc.gov/eid/article/26/7/20-0275_article

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Identification of a clinical compound losmapimod that blocks Lassa virus entry

Autor: Feihu Yan, Ying Guo, Logan Banadyga, Shihua He, Wenjun Zhu, Guo Jiamei, Xiangguo Qiu, Qing Chen, Tang Ke, Xiaoyu Zhang

Publikováno v: Antiviral Research

Lassa virus (LASV) causes Lassa hemorrhagic fever in humans and poses a significant threat to public health in West Africa. Current therapeutic treatments for Lassa fever are limited, making the development of novel countermeasures an urgent priority

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7959b5c1d1ee0e1523e05bbdcee331bf
https://doi.org/10.1016/j.antiviral.2019.03.014

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Type I interferon underlies severe disease associated with Junín virus infection in mice

Autor: Manuel L Penichet, Brady T. Hickerson, Kevin W. Bailey, Eric J. Sefing, Arnaud J. Van Wettere, Brian B. Gowen

Publikováno v: eLife, Vol 9 (2020)
Animal, Dairy, and Veterinary Science Student Research
eLife

Junín virus (JUNV) is one of five New World mammarenaviruses (NWMs) that causes fatal hemorrhagic disease in humans and is the etiological agent of Argentine hemorrhagic fever (AHF). The pathogenesis underlying AHF is poorly understood; however, a p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c1c02539a18c4f9c1438528d5a3272
https://doi.org/10.7554/elife.55352

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Virus-Like Particles: Applications in Reverse Vaccinology

Autor: Pastorini M, Goñi S, Lozano M, Borio C, De Ganzó A

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET

Vaccination has been one of the most successful and the most significant scientific advances in human health and life expectancy all around the globe. The World Health Organization considers that immunization should be recognized as the main componen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8829af480362fcacbb3155f192d85e5

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Transcription and replication mechanisms of Bunyaviridae and Arenaviridae L proteins

Autor: Juan Carlos de la Torre, Juan Reguera, Friedemann Weber, François Ferron

Publikováno v: Virus Research
Virus Research, 2017, 234, pp.118-134. ⟨10.1016/j.virusres.2017.01.018⟩
Virus Research, Elsevier, 2017, 234, pp.118-134. ⟨10.1016/j.virusres.2017.01.018⟩

Highlights • Bunyavirus and arenavirus are important public health threats. • Bunyavirus and arenavirus molecular biology, common and differential features. • Implications of LACV L protein structure for understanding viral RNA synthesis. • C

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d73b886d3d04cfa3d5af147cf89bb4e
https://hal.science/hal-01802833

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Membrane localization of Junín virus glycoproteins requires cholesterol and cholesterol rich membranes

Autor: Nélida A. Candurra, Sandra M. Cordo, Ayelén Valko, M. Guadalupe Martinez

Publikováno v: Biochemical and Biophysical Research Communications. 430:912-917

Arenavirus morphogenesis and budding occurs at cellular plasma membrane;however, the nature of membrane assembly sites remains poorly understood. In this study we examined the effect of different cholesterol-lowering agents on Junín virus (JUNV) mul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31b3be0af3059b39defd6d2e6dead71c
https://doi.org/10.1016/j.bbrc.2012.12.053

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