Zobrazeno 1 - 10
of 14 870
pro vyhledávání: '"JUN YU"'
Publikováno v:
Materials Research Letters, Vol 12, Iss 11, Pp 852-859 (2024)
The high yield ratio and low strain hardening ability of titanium alloys significantly limit their engineering applications. In this work, a Ti65Zr30Cu5 (at.%) alloy with nanoscale α laths was additively manufactured and achieved a high yield streng
Externí odkaz:
https://doaj.org/article/5664e9700e504fd7bed0f00fe53b96e9
Autor:
Yang Song, Wei Zhong, Harry Cheuk-Hay Lau, Yating Zhang, Huayu Guan, Mingxu Xie, Suki Ha, Diwen Shou, Yongjian Zhou, Hongzhi Xu, Jun Yu, Xiang Zhang
Publikováno v:
Engineering, Vol 41, Iss , Pp 204-215 (2024)
Carboxyl ester lipase (CEL), a pivotal enzyme involved in lipid metabolism, is recurrently mutated in obese mice. Here, we aimed to elucidate the functional significance, molecular mechanism, and therapeutic potential of CEL in metabolic dysfunction-
Externí odkaz:
https://doaj.org/article/cee61af6a9e2452aa805d19c15d00b50
Autor:
Jun Yu, Amit Kumar, Xuefeng Zhang, Charlotte Martin, Kevin Van holsbeeck, Pierre Raia, Antoine Koehl, Toon Laeremans, Jan Steyaert, Aashish Manglik, Steven Ballet, Andreas Boland, Miriam Stoeber
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract The μ-opioid receptor (μOR), a prototypical G protein-coupled receptor (GPCR), is the target of opioid analgesics such as morphine and fentanyl. Due to the severe side effects of current opioid drugs, there is considerable interest in deve
Externí odkaz:
https://doaj.org/article/03f1f018955843b7b595dac372889ec6
Autor:
Chenxi Zeng, Huihui Yue, Congjian Wang, Xuetao Ju, Tianlai Wang, Xiangning Fu, Qing Zhou, Huilan Zhang, Long He, Jun Yu, Yi Wang
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-16 (2024)
Abstract Background Idiopathic pulmonary fibrosis (IPF) is a chronic and lethal lung disorder for which effective treatments remain limited. Recent investigations revealed a potential link between altered glucose metabolism and the activation of fibr
Externí odkaz:
https://doaj.org/article/3a1735358082481e9f6a1430dedfa1fe
Autor:
Yiwen Chen, Junlei Zhang, Wendi Hu, Xiang Li, Ke Sun, Yan Shen, Min Zhang, Jian Wu, Shunliang Gao, Jun Yu, Risheng Que, Yun Zhang, Fuchun Yang, Weiliang Xia, Aibin Zhang, Xiaofeng Tang, Xueli Bai, Tingbo Liang
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 9, Iss 1, Pp 1-10 (2024)
Abstract Evidences regarding the feasibility of transcatheter arterial chemoembolization (TACE)-based therapy for unresectable hepatocellular carcinoma (uHCC) remains limited. This study aimed to investigate the efficacy and safety of TACE combined w
Externí odkaz:
https://doaj.org/article/0eeedb7d9d6b4b5f89fe82343013326f
Publikováno v:
BMC Ophthalmology, Vol 24, Iss 1, Pp 1-6 (2024)
Abstract Purpose To evaluate the effectiveness and safety of a method for repairing an eroded Ahmed glaucoma valve (AGV) tube using two short scleral tunnels made in tandem with a 22G needle instead of covering the eroded tube with another scleral gr
Externí odkaz:
https://doaj.org/article/dba6a28d47484cc492b4cf6a39759ada
Autor:
Huan WANG, Qinghua MENG, Yun LOU, Bin BAI, Weijie ZHU, Hongfang WANG, Yuxia KONG, Zechen FENG, Shuguang ZHAI, Jun YU, Yaru SUN, Yongzhong MA
Publikováno v:
环境与职业医学, Vol 41, Iss 9, Pp 1038-1042 (2024)
Background137Cs in atmospheric aerosol is the product of past nuclear weapon tests and nuclear accidents. When 137Cs is released into the atmosphere, it will deposit in dry land and marine environment, causing pollution of soil surface, water, agricu
Externí odkaz:
https://doaj.org/article/b172ee57c7804cfd89bb75520326d968
Publikováno v:
Precision Medical Sciences, Vol 13, Iss 3, Pp 172-180 (2024)
Abstract Gambogic acid is a natural bioactive compound from the brownish resin of the Garcinia hanburyi trees, which has been shown to induce cell death of cancer cells with a synergistic effect together with other compounds. In the present study, we
Externí odkaz:
https://doaj.org/article/e77d80d03c5e4e209775967c6e35b8b1
Autor:
Wenye Xu, Yuchen Zhang, Dongjiao Chen, Dan Huang, Yang Zhao, Wei Hu, Ling Lin, Yingzhi Liu, Shilan Wang, Judeng Zeng, Chuan Xie, Hung Chan, Qing Li, Huarong Chen, Xiaodong Liu, Sunny H. Wong, Jun Yu, Francis K. L. Chan, Matthew T. V. Chan, Siew C. Ng, William K. K. Wu, Lin Zhang
Publikováno v:
Gut Pathogens, Vol 16, Iss 1, Pp 1-13 (2024)
Abstract Background Fusobacterium nucleatum (F. nucleatum) is one of the key tumorigenic bacteria in colorectal cancer (CRC), yet how F. nucleatum is involved in colorectal cancer carcinogenesis remains unknown. Results In the present study, we carri
Externí odkaz:
https://doaj.org/article/b61bd6e59fff42d584fb0a93eec26fe1
Autor:
Yuanjian Fang, Yibo Liu, Luxi Chen, Junjie Wang, Jiahao Zhang, Haocheng Zhang, Sixuan Tian, Anke Zhang, Jianmin Zhang, John H. Zhang, Xiaoyu Wang, Jun Yu, Sheng Chen
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-14 (2024)
Abstract Background Early severe cerebral edema and chronic hydrocephalus are the primary cause of poor prognosis in patients with subarachnoid hemorrhage (SAH). This study investigated the role of cerebrospinal fluid (CSF) inflammatory cytokines and
Externí odkaz:
https://doaj.org/article/36065872bdd94f0e922607fc222f5e42