Zobrazeno 1 - 10
of 98
pro vyhledávání: '"JUAN L. CONTRERAS"'
Publikováno v:
Community Mental Health Journal. 59:77-84
Improving interactions between first responders and individuals experiencing behavioral crisis is a critical public health challenge. To gain insight into these interactions, key informant qualitative interviews were conducted with 25 Chicago stakeho
Publikováno v:
Community mental health journal. 59(1)
Improving interactions between first responders and individuals experiencing behavioral crisis is a critical public health challenge. To gain insight into these interactions, key informant qualitative interviews were conducted with 25 Chicago stakeho
Autor:
Alexander Tarakhovsky, Xueying Gu, Hainan Chen, Seung K. Kim, Rita Bottino, I-hsin Su, Juan L. Contreras
Publikováno v:
Genes & Development. 23:975-985
Proliferation of pancreatic islet β cells is an important mechanism for self-renewal and for adaptive islet expansion. Increased expression of the Ink4a/Arf locus, which encodes the cyclin-dependent kinase inhibitor p16INK4a and tumor suppressor p19
Pancreatic Resection with Islet Cell Autotransplant for the Treatment of Severe Chronic Pancreatitis
Publikováno v:
The American Surgeon. 74:530-537
Pancreatic resection can alleviate pain in properly selected patients with severe chronic pancreatitis (CP), although the apancreatic state causes “brittle” diabetes. Islet auto-transplantation (IAT) after resection can decrease diabetes-related
Autor:
Marianne G. Rots, Peter Dall, Daniel T. Rein, Gene P. Siegal, Rodney P. Rocconi, Dongquan Chen, Juan L. Contreras, J. Michael Mathis, Gerd J. Bauerschmitz, Alexander Stoff, Mariam A. Stoff-Khalili, David T. Curiel, Long P. Le, Marieke Everts, Masato Yamamoto, L Teng, Hidde J. Haisma, Angel A. Rivera
Publikováno v:
Cancer Gene Therapy, 13(6), 606-618. Nature Publishing Group
Whereas virotherapy has emerged as a novel and promising approach for neoplastic diseases, appropriate model systems have hampered preclinical evaluation of candidate conditionally replicative adenovirus agents (CRAds) with respect to liver toxicity.
Autor:
Dong Xie, Christopher Eckstein, Guadalupe Bilbao, Devin E. Eckhoff, Jimmy W. Mays, Juan L. Contreras, Cheryl A. Smyth
Publikováno v:
Biomaterials. 26:403-412
Functional poly(ethylene glycol) (PEG) derivatives, including monosuccinimidyl PEG (MSPEG) with molecular weight (MW) of 2000 (2 kDa) as well as 5 kDa and disuccinimidyl PEG (DSPEG) with MW of 3 and 6 kDa, were synthesized and characterized. They wer
Autor:
Devin E. Eckhoff, Christopher Eckstein, L. Frennete, Juan L. Contreras, Mario Vilatobá, Guadalupe Bilbao
Publikováno v:
Transplantation Proceedings. 37:399-403
Ischemia-reperfusion injury (I/R-I), which is unavoidable in liver transplantation, impairs liver regeneration and predisposes to liver failure. The three major mitogen-activated protein-kinases (MAPKs): ERK, p38, and JNK, are critical in the transmi
Autor:
Mario Vilatobá, Devin E. Eckhoff, Carlton J. Young, José A. Fernández, Cheryl A. Smyth, Christopher Eckstein, Guadalupe Bilbao, J. Anthony Thompson, Sharman E. Ringland, Juan L. Contreras, John H. Griffin
Publikováno v:
Diabetes. 53:2804-2814
Clinical studies indicate that significant loss of functional islet mass occurs in the peritransplant period. Islets are injured as a result of detrimental effects of brain death, pancreas preservation, islet isolation, hypoxia, hyperglycemia, and im
Autor:
David T. Curiel, Firoz G. Rahemtulla, Carlton J. Young, Christopher Eckstein, Devin E. Eckhoff, Guadalupe Bilbao, Juan L. Contreras, Cheryl A. Smyth, Dong Xie, J. Anthony Thompson, Jimmy W. Mays
Publikováno v:
Surgery. 136:537-547
Effective cytoprotection to xenoislets would circumvent the major tissue limitation for pancreatic islet transplantation (PIT). Cell-surface engineering with poly[ethylene glycol] (PEG) derivatives can successfully prevent antibody binding to the sur
Autor:
Carlton J. Young, Mario Vilatobá, Cheryl A. Smyth, Devin E. Eckhoff, Irshad H. Chaudry, Juan L. Contreras, J. Anthony Thompson, Guadalupe Bilbao, Firoz G. Rahemtulla, Christopher Eckstein
Publikováno v:
Surgery. 136:336-345
Background. Current isolation techniques recover only 20% to 50% of the pancreatic islets. Brain death (BI)) is characterized by activation of proinflammatory cytokines (PICs) with reduced islet yields and functionality. We previously reported that 1