Fetal baboons convert 18:3n-3 to 22:6n-3 in vivo. A stable isotope tracer study

Autor: Hm, Su, Mc, Huang, Nm, Saad, Peter Nathanielsz, Jt, Brenna

Publikováno v: Europe PubMed Central
CIÊNCIAVITAE

Using [13C]-tracers and direct fetal doses, we show for the first time that the fetal primate converts alpha-linolenic acid (18:3) to docosahexaenoic acid (22:6) in vivo, and we estimate the relative bioefficacy of the two substrates for brain 22:6 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::8242bf3e220c2d2c8d58baec340e5e43
https://pubmed.ncbi.nlm.nih.gov/11290830

Linoleate, alpha-linolenate, and docosahexaenoate recycling into saturated and monounsaturated fatty acids is a major pathway in pregnant or lactating adults and fetal or infant rhesus monkeys

Autor: Rc, Sheaff Greiner, Zhang Q, Kj, Goodman, Da, Giussani, Peter Nathanielsz, Jt, Brenna

Publikováno v: CIÊNCIAVITAE
Europe PubMed Central

Carbon recycling and desaturation and elongation of linoleate, alpha-linolenate and docosahexaenoate in ten fetuses and two nursing infants of chow-fed rhesus monkey mothers were studied in vivo using uniformly labeled tracer molecules and high preci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::697e07543c218ae27ec41d153ffc295c
https://pubmed.ncbi.nlm.nih.gov/9017518

Associations of plasma omega-6 and omega-3 fatty acids with overall and 19 site-specific cancers: A population-based cohort study in UK Biobank.

Autor: Zhang Y; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, USA., Sun Y; Department of Genetics, Franklin College of Arts and Sciences, University of Georgia, Athens, Georgia, USA., Song S; Department of Health Policy and Management, College of Public Health, University of Georgia, Athens, Georgia, USA., Khankari NK; Division of Genetic Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Brenna JT; Division of Nutritional Sciences, Cornell University, Ithaca, New York, USA.; Department of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, University of Texas at Austin, Austin, Texas, USA.; Department of Nutritional Sciences, College of Natural Sciences, University of Texas at Austin, Austin, Texas, USA.; Department of Chemistry, College of Natural Sciences, University of Texas at Austin, Austin, Texas, USA., Shen Y; Department of Epidemiology and Biostatistics, College of Public Health, University of Georgia, Athens, Georgia, USA., Ye K; Department of Genetics, Franklin College of Arts and Sciences, University of Georgia, Athens, Georgia, USA.; Institute of Bioinformatics, University of Georgia, Athens, Georgia, USA.

Publikováno v: International journal of cancer [Int J Cancer] 2024 Oct 17. Date of Electronic Publication: 2024 Oct 17.

Fatty acid desaturase insertion-deletion polymorphism rs66698963 predicts colorectal polyp prevention by the n-3 fatty acid eicosapentaenoic acid: a secondary analysis of the seAFOod polyp prevention trial.

Autor: Sun G; Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom., Li YN; Department of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, TX, United States; Department of Nutritional Sciences, The University of Texas at Austin, Austin, TX, United States., Davies JR; Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom., Block RC; Department of Public Health Sciences, University of Rochester, Rochester, NY, United States; Cardiovascular Division of the Department of Medicine, University of Rochester, Rochester, NY, United States; Center for Community Health and Prevention, University of Rochester, Rochester, NY, United States., Kothapalli KS; Department of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, TX, United States; Department of Nutritional Sciences, The University of Texas at Austin, Austin, TX, United States., Brenna JT; Department of Pediatrics, Dell Pediatric Research Institute, Dell Medical School, The University of Texas at Austin, TX, United States; Department of Nutritional Sciences, The University of Texas at Austin, Austin, TX, United States., Hull MA; Leeds Institute of Medical Research, University of Leeds, Leeds, United Kingdom. Electronic address: m.a.hull@leeds.ac.uk.

Publikováno v: The American journal of clinical nutrition [Am J Clin Nutr] 2024 Aug; Vol. 120 (2), pp. 360-368. Date of Electronic Publication: 2024 Jun 13.

Liquid Chromatography Coupled to Isotope Ratio Mass Spectrometry Expanded to Include Organic Mobile Phases.

Autor: Tobias HJ; Dell Pediatric Research Institute, Dell Medical School, University of Texas at Austin, 1400 Barbara Jordan Boulevard, Austin, Texas 78723, United States., Jones A; Activated Research Company, 7561 Corporate Way, Eden Prairie, Minnesota 55344, United States., Saunders TR; Activated Research Company, 7561 Corporate Way, Eden Prairie, Minnesota 55344, United States., Brenna JT; Dell Pediatric Research Institute, Dell Medical School, University of Texas at Austin, 1400 Barbara Jordan Boulevard, Austin, Texas 78723, United States.; Department of Chemistry, College of Natural Sciences, University of Texas at Austin, Austin, Texas 78712-1224, United States.

Publikováno v: Analytical chemistry [Anal Chem] 2024 May 14; Vol. 96 (19), pp. 7348-7352. Date of Electronic Publication: 2024 May 02.