A sandwich ELISA for the quantification of the anticancer peptide CIGB-552 in human plasma.

Autor: Gómez Hernández NA; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: nivaldo.gomez@cigb.edu.cu., Pérez GL; Chemistry-Physics Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: gilda.lemos@cigb.edu.cu., Arteaga AV; Chemistry-Physics Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: amalia.vazquez@cigb.edu.cu., Garay Pérez HE; Peptide Synthesis Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: hilda.garay@cigb.edu.cu., Arguellez BO; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: brizaida.oliva@cigb.edu.cu., Rico AC; Chemistry-Physics Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: ania.cabrales@cigb.edu.cu., Guardia AL; Monoclonal Antibody Production Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: airela.llamo@cigb.edu.cu., Fernández Massó JR; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Havana, Cuba. Electronic address: julio.fernandez@cigb.edu.cu.

Publikováno v: Analytical biochemistry [Anal Biochem] 2024 Nov 26, pp. 115725. Date of Electronic Publication: 2024 Nov 26.

The effects of Phycocyanobilin on experimental arthritis involve the reduction in nociception and synovial neutrophil infiltration, inhibition of cytokine production, and modulation of the neuronal proteome.

Autor: Marín-Prida J; Center for Research and Biological Evaluations, Institute of Pharmacy and Food, University of Havana, Havana, Cuba., Rodríguez-Ulloa A; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Besada V; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Yongzhou Zhong Gu Biotechnology Co. Ltd, Yongzhou, China., Llopiz-Arzuaga A; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; Department of Cellular Engineering and Biocatalysis , Institute of Biotechnology, National Autonomous University of Mexico (UNAM), Cuernavaca, Mexico., Batista NV; Laboratory of Immunopharmacology, Department of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Hernández-González I; Department of Non-Clinical Research, Isotopes Center, San José de Las Lajas, Mayabeque, Cuba., Pavón-Fuentes N; Immunochemical Department, International Center for Neurological Restoration (CIREN), Havana, Cuba., Marciano Vieira ÉL; Translational Psychoneuroimmunology Group, School of Medicine, Federal University of Minas Gerais (UFMG), Belo Horizonte, Brazil., Falcón-Cama V; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; Departments of Physiological or Morphological Sciences, Latin American School of Medicine (ELAM), Havana, Cuba., Acosta EF; Department of Characterization, Center for Advanced Studies of Cuba, Havana, Cuba., Martínez-Donato G; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Cervantes-Llanos M; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Lingfeng D; China-Cuba Biotechnology Joint Innovation Center (CCBJIC), Yongzhou Zhong Gu Biotechnology Co. Ltd, Yongzhou, China., González LJ; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Fernández-Massó JR; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba., Guillén-Nieto G; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; Departments of Physiological or Morphological Sciences, Latin American School of Medicine (ELAM), Havana, Cuba., Pentón-Arias E; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; Departments of Physiological or Morphological Sciences, Latin American School of Medicine (ELAM), Havana, Cuba., Amaral FA; Laboratory of Immunopharmacology, Department of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Teixeira MM; Laboratory of Immunopharmacology, Department of Biochemistry and Immunology, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil., Pentón-Rol G; Division of Biomedical Research, Center for Genetic Engineering and Biotechnology, Havana, Cuba.; Departments of Physiological or Morphological Sciences, Latin American School of Medicine (ELAM), Havana, Cuba.

Publikováno v: Frontiers in immunology [Front Immunol] 2023 Oct 23; Vol. 14, pp. 1227268. Date of Electronic Publication: 2023 Oct 23 (Print Publication: 2023).

The Anticancer Peptide CIGB-552 Exerts Anti-Inflammatory and Anti-Angiogenic Effects through COMMD1.

Autor: Daghero H; Cell Biology Unit, Institut Pasteur Montevideo, Mataojo 2020, Montevideo 11400, Uruguay., Fernández Massó JR; Department of Genomic, Center for Genetic Engineering and Biotechnology, Cubanacan, P.O. Box 6162, Havana 10600, Cuba., Astrada S; Cell Biology Unit, Institut Pasteur Montevideo, Mataojo 2020, Montevideo 11400, Uruguay.; Institut d'Optique d'Aquitaine, Université de Bordeaux, 33400 Talence, France., Guerra Vallespí M; Pharmaceutical Department, Center for Genetic Engineering and Biotechnology, Cubanacan, P.O. Box 6162, Havana 10600, Cuba., Bollati-Fogolín M; Cell Biology Unit, Institut Pasteur Montevideo, Mataojo 2020, Montevideo 11400, Uruguay.

Publikováno v: Molecules (Basel, Switzerland) [Molecules] 2020 Dec 31; Vol. 26 (1). Date of Electronic Publication: 2020 Dec 31.

Beneficial effects of oral administration of C-Phycocyanin and Phycocyanobilin in rodent models of experimental autoimmune encephalomyelitis.

Autor: Cervantes-Llanos M; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Lagumersindez-Denis N; Center for Research and Biological Evaluations (CEIEB), Institute of Pharmacy and Food, University of Havana, Ave. 23 e/ 214 y 222, La Lisa, Havana, PO Box 430, Cuba., Marín-Prida J; Center for Research and Biological Evaluations (CEIEB), Institute of Pharmacy and Food, University of Havana, Ave. 23 e/ 214 y 222, La Lisa, Havana, PO Box 430, Cuba., Pavón-Fuentes N; International Center for Neurological Restoration (CIREN), Ave. 25 e/ 158 y 160, Playa, Havana, PO Box 11300, Cuba., Falcon-Cama V; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Piniella-Matamoros B; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Camacho-Rodríguez H; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Fernández-Massó JR; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Valenzuela-Silva C; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Raíces-Cruz I; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba., Pentón-Arias E; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba; Latin American School of Medicine (ELAM), Carretera Panamericana Km 3½, Sta. Fe, Playa, PO Box 19108, Havana, Cuba., Teixeira MM; Laboratory of Immunopharmacology, Department of Biochemistry and Immunology, Institute of Biological Sciences, Federal University of Minas Gerais, Av. Antônio Carlos, 6627, Pampulha, Belo Horizonte, MG, Brazil., Pentón-Rol G; Center for Genetic Engineering and Biotechnology (CIGB), Ave. 31 e/ 158 y 190, Cubanacán, Playa, Havana, PO Box 6162, Cuba. Electronic address: http://www.cigb.edu.cu.

Publikováno v: Life sciences [Life Sci] 2018 Feb 01; Vol. 194, pp. 130-138. Date of Electronic Publication: 2017 Dec 27.

Phycocyanobilin promotes PC12 cell survival and modulates immune and inflammatory genes and oxidative stress markers in acute cerebral hypoperfusion in rats.

Autor: Marín-Prida J; Centre for Research and Biological Evaluations (CEIEB), Institute of Pharmacy and Food, University of Havana, Ave. 23 e/ 214 y 222, La Lisa, PO Box: 430, Havana, Cuba., Pavón-Fuentes N, Llópiz-Arzuaga A, Fernández-Massó JR, Delgado-Roche L, Mendoza-Marí Y, Santana SP, Cruz-Ramírez A, Valenzuela-Silva C, Nazábal-Gálvez M, Cintado-Benítez A, Pardo-Andreu GL, Polentarutti N, Riva F, Pentón-Arias E, Pentón-Rol G

Publikováno v: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 2013 Oct 01; Vol. 272 (1), pp. 49-60. Date of Electronic Publication: 2013 Jun 02.