Shrinking lungs syndrome in systemic lupus erythematosus: improvement with inhaled beta-agonist therapy

Autor: Joan Albert Barberà, Josep Font, Ricard Cervera, JR Badia, F. J. Muñoz-Rodriguez, Miguel Ingelmo, C Miret

Publikováno v: Scopus-Elsevier

The pathogenesis and therapy of shrinking lungs syndrome in patients with systemic lupus erythematosus remains controversial. It has been previously reported that corticosteroid treatment can be effective. We report a patient with shrinking lungs syn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e01e0942e11c7e5b0ab1c42650a61a4
https://pubmed.ncbi.nlm.nih.gov/9175030

Detailed stratified GWAS analysis for severe COVID-19 in four European populations.

Autor: Degenhardt F; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Juzenas S; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Life Science Centre, Institute of Biotechnology, Vilnius University, Vilnius, Lithuania., Lerga-Jaso J; Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Barcelona, Spain., Wendorff M; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Maya-Miles D; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain., Uellendahl-Werth F; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., ElAbd H; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Rühlemann MC; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Institute for Medical Microbiology and Hospital Epidemiology, Hannover Medical School, Hannover, Germany., Arora J; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA., Özer O; Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Research Unit for Evolutionary Immunogenomics, Department of Biology, University of Hamburg, Hamburg, Germany., Lenning OB; Research Department, Stavanger University Hospital, Stavanger, Norway.; Randaberg Municipality, Stavanger, Norway., Myhre R; Division of Health Data and Digitalization, Department of Genetics and Bioinformatics (HDGB), Norwegian Institute of Public Health, Oslo, Norway., Vadla MS; Randaberg Municipality, Stavanger, Norway.; Department of Quality and Health Technology, Faculty of Health Sciences, University of Stavanger, Stavanger, Norway., Wacker EM; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Wienbrandt L; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Blandino Ortiz A; Department of Intensive Care, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., de Salazar A; Ibs.Granada Instituto de Investigación Biosanitaria, Granada, Spain.; Microbiology Unit. Hospital Universitario Clinico San Cecilio, Granada, Spain., Garrido Chercoles A; Clinical Biochemistry Department, Osakidetza Basque Health Service, Donostialdea Integrated Health Organisation, San Sebastian, Spain., Palom A; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Barcelona, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Ruiz A; Research Center and Memory Clinic, Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Garcia-Fernandez AE; Department of Biochemistry, University Hospital Vall d'Hebron, Barcelona, Spain., Blanco-Grau A; Department of Biochemistry, University Hospital Vall d'Hebron, Barcelona, Spain., Mantovani A; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Zanella A; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Holten AR; Department of Acute Medicine, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, University of Oslo, Oslo, Norway., Mayer A; Charite Universitätsmedizin Berlin, Berlin, Germany., Bandera A; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Cherubini A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Protti A; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Aghemo A; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Gerussi A; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy.; Division of Gastroenterology, School of Medicine and Surgery, Center for Autoimmune Liver Diseases, University of Milano-Bicocca, Milan, Italy., Ramirez A; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany.; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany.; Department of Psychiatry, Glenn Biggs Institute for Alzheimer's and Neurodegenerative Diseases, San Antonio, TX, USA., Braun A; Charite Universitätsmedizin Berlin, Berlin, Germany., Nebel A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Barreira A; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Lleo A; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Teles A; Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Research Unit for Evolutionary Immunogenomics, Department of Biology, University of Hamburg, Hamburg, Germany., Kildal AB; Department of Anesthesiology and Intensive Care, University Hospital of North Norway, Tromsø, Norway., Biondi A; Pediatric Departement, Centro Tettamanti-European Reference Network (ERN) PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM/Ospedale, San Gerardo, Italy., Caballero-Garralda A; Biochemistry Department, Echevarne Laboratory, Barcelona, Spain., Ganna A; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Gori A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Centre for Multidisciplinary Research in Health Science (MACH), University of Milan, Milan, Italy., Glück A; Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Lind A; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Tanck A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Hinney A; Department of Child and Adolescent Psychiatry, University Hospital Essen, University of Duisburg-Essen, Essen, Germany., Carreras Nolla A; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Fracanzani AL; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Peschuck A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Cavallero A; Laboratory of Microbiology, San Gerardo Hospital, Monza, Italy., Dyrhol-Riise AM; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious diseases, Oslo University Hospital, Oslo, Norway., Ruello A; Humanitas Gavazzeni-Castelli, Bergamo, Italy., Julià A; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Barcelona, Spain., Muscatello A; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Pesenti A; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Voza A; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Rando-Segura A; Microbiology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Universitat Autònoma de Barcelona, Bellatera, Spain., Solier A; Department of Respiratory Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Respiratorias (CIBERES), University of Alcalá, Madrid, Spain., Schmidt A; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Cortes B; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Mateos B; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Gastroenterology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Nafria-Jimenez B; Clinical Biochemistry Department, Osakidetza Basque Health Service, Donostialdea Integrated Health Organisation, San Sebastian, Spain., Schaefer B; Department of Medicine I, Gastroenterology, Hepatology and Endocrinology, Medical University of Innsbruck, Innsbruck, Austria.; Christian Doppler Laboratory of Iron and Phosphate Biology at the Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria., Jensen B; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty Heinrich Heine University, Duesseldorf, Germany., Bellinghausen C; Department of Respiratory Medicine and Allergology, University Hospital, Goethe University, Frankfurt am Main, Germany., Maj C; Institute of Genomic Statistics and Bioinformatics, University Hospital Bonn, Medical Faculty University of Bonn, Bonn, Germany., Ferrando C; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., de la Horra C; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain., Quereda C; Department of Infectious Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Skurk C; Charite Universitätsmedizin Berlin, Berlin, Germany., Thibeault C; Charite Universitätsmedizin Berlin, Berlin, Germany., Scollo C; Department of Transfusion Medicine and Haematology Laboratory, San Gerardo Hospital, Monza, Italy., Herr C; Department of Internal Medicine V-Pneumology, Allergology and Intensive Care Medicine, University Hospital Saarland, Homburg, Germany., Spinner CD; Department of Internal Medicine II, School of Medicine, University Hospital rechts der Isar, Technical University of Munich, Munich, Germany., Gassner C; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Institute of Translational Medicine, Private University in the Principality of Liechtenstein (UFL), Triesen, Liechtenstein., Lange C; Respiratory Medicine and International Health, University of Lübeck, Lübeck, Germany.; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.; Clinical Tuberculosis Unit, German Center for Infection Research (DZIF), Borstel, Germany., Hu C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Paccapelo C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Lehmann C; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Cologne, Germany., Angelini C; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Cappadona C; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Azuure C; Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Research Unit for Evolutionary Immunogenomics, Department of Biology, University of Hamburg, Hamburg, Germany., Bianco C; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Cea C; Department of Biochemistry, University Hospital Vall d'Hebron, Barcelona, Spain., Sancho C; Osakidetza Basque Health Service, Basurto University Hospital, Respiratory Service, Bilbao, Spain., Hoff DAL; Department of Clinical and Molecular Medicine, Faculty of Medicine and Health Sciences, Norwegian University of Science and Technology, Trondheim, Norway.; Department of Medicine, Møre and Romsdal Hospital Trust, Ålesund, Norway., Galimberti D; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Prati D; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Haschka D; Department of Internal Medicine II, Medical University of Innsbruck, Innsbruck, Austria., Jiménez D; Department of Respiratory Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Respiratorias (CIBERES), University of Alcalá, Madrid, Spain., Pestaña D; Department of Anesthesiology and Critical Care, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Toapanta D; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Muñiz-Diaz E; Immunohematology Department, Banc de Sang i Teixits, Autonomous University of Barcelona, Barcelona, Spain., Azzolini E; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Sandoval E; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Binatti E; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy.; Division of Gastroenterology, School of Medicine and Surgery, Center for Autoimmune Liver Diseases, University of Milano-Bicocca, Milan, Italy., Scarpini E; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Helbig ET; Charite Universitätsmedizin Berlin, Berlin, Germany., Casalone E; Department of Medical Sciences, Università degli Studi di Torino, Turin, Italy., Urrechaga E; Osakidetza Basque Health Service, Galdakao Hospital, Respiratory Service, Galdakao, Spain.; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Paraboschi EM; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Pontali E; Department of Infectious Diseases, E.O. Ospedali Galliera, Genova, Italy., Reverter E; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Calderón EJ; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain., Navas E; Department of Infectious Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Solligård E; Geminicenter for Sepsis Research, Institute of Circulation and Medical Imaging (ISB), NTNU, Trondheim, Norway.; Clinic of Anesthesia and Intensive Care, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway., Contro E; Accident and Emergency and Emergency Medicine Unit, San Gerardo Hospital, Monza, Italy., Arana-Arri E; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Aziz F; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Garcia F; Ibs.Granada Instituto de Investigación Biosanitaria, Granada, Spain.; Microbiology Unit. Hospital Universitario Clinico San Cecilio, Granada, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III (ISCIII), Madrid, Spain., García Sánchez F; Histocompatibilidad y Biologia Molecular, Centro de Transfusion de Madrid, Madrid, Spain., Ceriotti F; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Martinelli-Boneschi F; Department of Pathophysiology and Transplantation, Dino Ferrari Center, University of Milan, Milan, Italy.; Neurology Unit, IRCCS Fondazione Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Peyvandi F; Department of Pathophysiology and Transplantation, University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Angelo Bianchi Bonomi Hemophilia and Thrombosis Center, Milan, Italy., Kurth F; Charite Universitätsmedizin Berlin, Berlin, Germany.; Department of Tropical Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany.; Department of Medicine I, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany., Blasi F; Respiratory Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Department of Pathophysiology and Transplantation, Università degli Studi di Milano, Milan, Italy., Malvestiti F; University of Milan, Milan, Italy., Medrano FJ; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain.; Internal Medicine Department, Virgen del Rocio University Hospital, Sevilla, Spain., Mesonero F; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Gastroenterology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Rodriguez-Frias F; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Barcelona, Spain.; Department of Biochemistry, University Hospital Vall d'Hebron, Barcelona, Spain.; Microbiology Department, Hospital Universitari Vall d'Hebron, Barcelona, Spain.; Universitat Autònoma de Barcelona, Bellatera, Spain.; Biochemistry Department, University Hospital Vall d'Hebron, Barcelona, Spain., Hanses F; Emergency Department, University Hospital Regensburg, Regensburg, Germany.; Department for Infectious Diseases and Infection Control, University Hospital Regensburg, Regensburg, Germany., Müller F; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Hemmrich-Stanisak G; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Bellani G; Department Emergency, Anesthesia and Intensive Care, San Gerardo Hospital, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Grasselli G; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Pezzoli G; Fondazione Grigioni per il Morbo di Parkinson and Parkinson Institute, ASST Gaetano Pini-CTO, Milan, Italy., Costantino G; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Albano G; Humanitas Gavazzeni-Castelli, Bergamo, Italy., Cardamone G; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Bellelli G; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Acute Geriatric Unit, San Gerardo Hospital, Monza, Italy., Citerio G; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Neurointensive Care Unit, San Gerardo Hospital, Monza, Italy., Foti G; Department Emergency, Anesthesia and Intensive Care, San Gerardo Hospital, Monza, Italy.; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Lamorte G; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Matullo G; Department of Medical Sciences, Università degli Studi di Torino, Turin, Italy., Baselli G; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Kurihara H; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Neb H; Department of Anesthesiology, Intensive Care Medicine and Pain Therapy, University Hospital Frankfurt, Frankfurt am Main, Germany., My I; IRCCS Humanitas Research Hospital, Milan, Italy., Kurth I; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany., Hernández I; Research Center and Memory Clinic, Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Pink I; Department of Pneumology, Hannover Medical School, Hannover, Germany., de Rojas I; Research Center and Memory Clinic, Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Galván-Femenia I; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Holter JC; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Afset JE; Osakidetza Basque Health Service, Basurto University Hospital, Respiratory Service, Bilbao, Spain.; Department of Medical Microbiology, Clinic of Laboratory Medicine, St. Olavs hospital, Trondheim, Norway., Heyckendorf J; Respiratory Medicine and International Health, University of Lübeck, Lübeck, Germany.; Division of Clinical Infectious Diseases, Research Center Borstel, Borstel, Germany.; Clinical Tuberculosis Unit, German Center for Infection Research (DZIF), Borstel, Germany., Kässens J; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Damås JK; Department of Infectious Diseases, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.; Department of Clinical and Molecular Medicine, NTNU, Trondheim, Norway., Rybniker J; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Centre for Infection Research (DZIF), Cologne, Germany., Altmüller J; Cologne Center for Genomics (CCG), University of Cologne, Cologne, Germany., Ampuero J; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville, Spain., Martín J; Institute of Parasitology and Biomedicine Lopez-Neyra, CSIC, Granada, Spain., Erdmann J; Institute for Cardiogenetics, University of Lübeck, Lübeck, Germany.; German Research Center for Cardiovascular Research, Lübeck, Germany.; University Heart Center Lübeck, Lübeck, Germany., Banales JM; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain., Badia JR; Respiratory ICU, Institut Clínic Respiratory, Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Dopazo J; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; Bioinformatics Area, Fundación Progreso y Salud, and Institute of Biomedicine of Sevilla (IBIS), Sevilla, Spain., Schneider J; Department of Internal Medicine V-Pneumology, Allergology and Intensive Care Medicine, University Hospital Saarland, Homburg, Germany., Bergan J; Department of Research, Ostfold Hospital Trust, Gralum, Norway., Barretina J; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Walter J; Department of Genetics & Epigenetics, Saarland University, Saarbrücken, Germany., Hernández Quero J; Ibs.Granada Instituto de Investigación Biosanitaria, Granada, Spain.; Department of Infectious Diseases, Hospital Universitario Clinico San Cecilio, Granada, Spain., Goikoetxea J; Infectious Diseases Service, Osakidetza, Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Delgado J; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain., Guerrero JM; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain., Fazaal J; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Kraft J; Charite Universitätsmedizin Berlin, Berlin, Germany., Schröder J; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Risnes K; Department of Clinical and Molecular Medicine, NTNU, Trondheim, Norway.; Department of Research, St. Olav Hospital, Trondheim University Hospital, Trondheim, Norway., Banasik K; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Müller KE; Medical Department, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway., Gaede KI; Research Center Borstel, BioMaterialBank Nord, Borstel, Germany.; German Center for Lung Research (DZL), Airway Research Center North (ARCN), Borstel, Germany.; Popgen 2.0 Network (P2N), Kiel, Germany., Garcia-Etxebarria K; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain., Tonby K; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Infectious diseases, Oslo University Hospital, Oslo, Norway., Heggelund L; Medical Department, Drammen Hospital, Vestre Viken Hospital Trust, Drammen, Norway.; Department of Clinical Science, University of Bergen, Bergen, Norway., Izquierdo-Sanchez L; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain.; Biodonostia Health Research Institute, Donostia University Hospital, San Sebastian, Spain., Bettini LR; Pediatric Departement, Centro Tettamanti-European Reference Network (ERN) PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM/Ospedale, San Gerardo, Italy., Sumoy L; Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Sander LE; Charite Universitätsmedizin Berlin, Berlin, Germany., Lippert LJ; Charite Universitätsmedizin Berlin, Berlin, Germany., Terranova L; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Nkambule L; Analytic and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA.; Stanley Center for Psychiatric Research & Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Knopp L; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty Heinrich Heine University, Duesseldorf, Germany., Gustad LT; Geminicenter for Sepsis Research, Institute of Circulation and Medical Imaging (ISB), NTNU, Trondheim, Norway.; Clinic of Medicine and Rehabilitation, Levanger Hospital, Nord-Trondelag Hospital Trust, Levanger, Norway., Garbarino L; HLA Laboratory, E.O. Ospedali Galliera, Genova, Italy., Santoro L; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Téllez L; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Gastroenterology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Roade L; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Department of Respiratory Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Ostadreza M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Intxausti M; Osakidetza Basque Health Service, Basurto University Hospital, Respiratory Service, Bilbao, Spain., Kogevinas M; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; ISGlobal, Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Riveiro-Barciela M; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Universitat Autònoma de Barcelona, Bellatera, Spain., Berger MM; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Schaefer M; Stefan-Morsch-Stiftung, Birkenfeld, Germany., Niemi MEK; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Gutiérrez-Stampa MA; Osakidetza, OSI Donostialdea, Altza Primary Care, Biodonostia Health Research Institute, San Sebastián, Spain., Carrabba M; Internal Medicine Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Figuera Basso ME; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Valsecchi MG; Center of Bioinformatics, Biostatistics and Bioimaging, School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy., Hernandez-Tejero M; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Vehreschild MJGT; Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany., Manunta M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Acosta-Herrera M; Institute of Parasitology and Biomedicine Lopez-Neyra, CSIC, Granada, Spain., D'Angiò M; Pediatric Departement, Centro Tettamanti-European Reference Network (ERN) PaedCan, EuroBloodNet, MetabERN-University of Milano-Bicocca-Fondazione MBBM/Ospedale, San Gerardo, Italy., Baldini M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Cazzaniga M; Phase 1 Research Centre, ASST Monza, School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy., Grimsrud MM; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Department of Transplantation Medicine, Norwegian PSC Research Center, Oslo University Hospital Rikshospitalet, Oslo, Norway., Cornberg M; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Nöthen MM; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Marquié M; Research Center and Memory Clinic, Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Castoldi M; Humanitas Gavazzeni-Castelli, Bergamo, Italy., Cordioli M; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Cecconi M; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., D'Amato M; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.; Gastrointestinal Genetics Lab, CIC bioGUNE-BRTA, Derio, Spain.; Department of Medicine and Surgery, LUM University, Casamassima, Italy., Augustin M; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Cologne, Germany., Tomasi M; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Boada M; Research Center and Memory Clinic, Ace Alzheimer Center Barcelona, Universitat Internacional de Catalunya, Barcelona, Spain.; CIBERNED, Network Center for Biomedical Research in Neurodegenerative Diseases, National Institute of Health Carlos III, Madrid, Spain., Dreher M; Department of Pneumology and Intensive Care Medicine, University Hospital Aachen, Aachen, Germany., Seilmaier MJ; Munich Clinic Schwabing, Academic Teaching Hospital, Ludwig-Maximilians-University (LMU), Munich, Germany., Joannidis M; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria., Wittig M; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Mazzocco M; HLA Laboratory, E.O. Ospedali Galliera, Genova, Italy., Ciccarelli M; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Rodríguez-Gandía M; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Gastroenterology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Bocciolone M; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Miozzo M; University of Milan, Milan, Italy.; Internal Medicine Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Imaz Ayo N; Biocruces Bizkaia Health Research Institute, Barakaldo, Spain., Blay N; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Chueca N; Microbiology Unit. Hospital Universitario Clinico San Cecilio, Granada, Spain., Montano N; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Braun N; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; University Hospital Schleswig-Holstein, Kiel, Germany., Ludwig N; Department of Human Genetics, Center of Human and Molecular Biology, University Hospital Saarland, Homburg/Saar, Germany., Marx N; Department of Internal Medicine I, RWTH Aachen University Hospital, Aachen, Germany., Martínez N; Department of Anesthesiology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), Madrid, Spain., Cornely OA; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Cologne, Germany.; Faculty of Medicine and University Hospital Cologne, Clinical Trials Centre Cologne (ZKS Köln), University of Cologne, Cologne, Germany., Witzke O; Department of Infectious Diseases, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Palmieri O; Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Faverio P; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Pulmonary Unit, San Gerardo Hospital, Monza, Italy., Preatoni P; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Bonfanti P; School of Medicine and Surgery, University of Milano-Bicocca, Milan, Italy.; Infectious Diseases Unit, San Gerardo Hospital, Monza, Italy., Omodei P; Humanitas Clinical and Research Center, IRCCS, Milan, Italy., Tentorio P; IRCCS Humanitas Research Hospital, Milan, Italy., Castro P; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain., Rodrigues PM; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain.; Ikerbasque, Basque Foundation for Science, Bilbao, Spain.; Biodonostia Health Research Institute, Donostia University Hospital, San Sebastian, Spain., España PP; Osakidetza Basque Health Service, Galdakao Hospital, Respiratory Service, Galdakao, Spain., Hoffmann P; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Schommers P; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Cologne, Germany., Suwalski P; Charite Universitätsmedizin Berlin, Berlin, Germany., de Pablo R; Department of Intensive Care, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Ferrer R; Intensive Care Department, Vall d'Hebron University Hospital, SODIR-VHIR research group, Barcelona, Spain., Bals R; Department of Internal Medicine V-Pneumology, Allergology and Intensive Care Medicine, University Hospital Saarland, Homburg, Germany., Gualtierotti R; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Gallego-Durán R; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain., Nieto R; Department of Respiratory Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Respiratorias (CIBERES), University of Alcalá, Madrid, Spain., Carpani R; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Morilla R; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain., Badalamenti S; IRCCS Humanitas Research Hospital, Milan, Italy., Haider S; Department of Medicine, Møre & Romsdal Hospital Trust, Molde, Norway., Ciesek S; Institute of Medical Virology, University Hospital Frankfurt, Goethe University, Frankfurt am Main, Germany.; German Centre for Infection Research (DZIF), Frankfurt am Main, Germany., May S; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Bombace S; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Marsal S; Vall d'Hebron Institut de Recerca (VHIR), Vall d'Hebron Hospital Universitari, Barcelona, Spain., Pigazzini S; Institute for Molecular Medicine Finland, University of Helsinki, Helsinki, Finland., Klein S; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria., Pelusi S; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Wilfling S; Department for Infectious Diseases and Infection Control, University Hospital Regensburg, Regensburg, Germany.; Zentrum für Humangenetik Regensburg, Regensburg, Germany.; Department of Neurology, Bezirksklinikum Regensburg, University of Regensburg, Regensburg, Germany., Bosari S; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Volland S; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Brunak S; Novo Nordisk Foundation Center for Protein Research, Disease Systems Biology, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Raychaudhuri S; Program in Medical and Population Genetics, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.; Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, MA, USA.; Department of Biomedical Informatics, Harvard Medical School, Boston, MA, USA.; Center for Data Sciences, Brigham and Women's Hospital, Boston, MA, USA.; Centre for Genetics and Genomics Versus Arthritis, Centre for Musculoskeletal Research, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK., Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Heilmann-Heimbach S; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Aliberti S; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Ripke S; Charite Universitätsmedizin Berlin, Berlin, Germany., Dudman S; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Department of Microbiology, Oslo University Hospital, Oslo, Norway., Wesse T; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Zheng T; School of Biological Sciences, Monash University, Clayton, VIC, Australia., Bahmer T; Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Eggermann T; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany., Illig T; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Brenner T; Department of Anesthesiology and Intensive Care Medicine, University Hospital Essen, University Duisburg-Essen, Essen, Germany., Pumarola T; Department of Microbiology, University Hospital Vall d'Hebron, Barcelona, Spain.; Autonoma University of Barcelona, Barcelona, Spain., Feldt T; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty Heinrich Heine University, Duesseldorf, Germany., Folseraas T; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Department of Transplantation Medicine, Norwegian PSC Research Center, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Division for Cancer Medicine, Surgery and Transplantation, Section for Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Gonzalez Cejudo T; Biochemistry Unit, Hospital Universitario Clinico San Cecilio, Granada, Spain., Landmesser U; Berlin Institute of Health, Charite Universitätsmedizin Berlin, Berlin Germany., Protzer U; Institute of Virology, Technical University Munich/Helmholtz Zentrum München, Munich, Germany.; German Center for Infection Research (DZIF), Munich, Germany., Hehr U; Zentrum für Humangenetik Regensburg, Regensburg, Germany., Rimoldi V; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Monzani V; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Skogen V; Department of Infectious Diseases, University Hospital of North Norway, Tromsø, Norway.; Faculty of Health Sciences, UIT The Arctic University of Norway, Norway., Keitel V; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Duesseldorf, Medical Faculty Heinrich Heine University, Duesseldorf, Germany., Kopfnagel V; Hannover Unified Biobank, Hannover Medical School, Hannover, Germany., Friaza V; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Consejo Superior de Investigaciones Científicas, Sevilla, Spain., Andrade V; Division of Neurogenetics and Molecular Psychiatry, Department of Psychiatry and Psychotherapy, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department of Neurodegenerative Diseases and Geriatric Psychiatry, University Hospital Bonn, Medical Faculty, Bonn, Germany., Moreno V; Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (CIBERESP), Madrid, Spain.; Catalan Institute of Oncology (ICO), Barcelona, Spain.; Bellvitge Biomedical Research Institute (IDIBELL), Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Albrecht W; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Peter W; Stefan-Morsch-Stiftung, Birkenfeld, Germany.; Faculty of Medicine and University Hospital Cologne, Institute for Transfusion Medicine, University of Cologne, Cologne, Germany., Poller W; Charite Universitätsmedizin Berlin, Berlin, Germany., Farre X; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Yi X; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany., Wang X; Charite Universitätsmedizin Berlin, Berlin, Germany., Khodamoradi Y; Department of Internal Medicine, Infectious Diseases, University Hospital Frankfurt & Goethe University Frankfurt, Frankfurt am Main, Germany., Karadeniz Z; Charite Universitätsmedizin Berlin, Berlin, Germany., Latiano A; Gastroenterology Unit, Fondazione IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy., Goerg S; Institute of Transfusionsmedicine, University Hospital Schleswig-Holstein (UKSH), Kiel, Germany., Bacher P; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Institute of Immunology, Christian-Albrechts-University of Kiel and UKSH Schleswig-Holstein, Kiel, Germany., Koehler P; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Department I of Internal Medicine, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany., Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; Klinik für Innere Medizin I, Universitätsklinikum Schleswig-Holstein, Kiel, Germany., Zoller H; Department of Medicine I, Gastroenterology, Hepatology and Endocrinology, Medical University of Innsbruck, Innsbruck, Austria.; Christian Doppler Laboratory of Iron and Phosphate Biology at the Department of Medicine I, Medical University of Innsbruck, Innsbruck, Austria., Schulte EC; Institute of Virology, Technical University Munich/Helmholtz Zentrum München, Munich, Germany.; Institute of Psychiatric Phenomics and Genomics, University Medical Center, University of Munich, Munich, Germany.; Department of Psychiatry, University Medical Center, University of Munich, Munich, Germany., Heidecker B; Charite Universitätsmedizin Berlin, Berlin, Germany., Ludwig KU; Institute of Human Genetics, University of Bonn School of Medicine & University Hospital Bonn, Bonn, Germany., Fernández J; Hospital Clinic, University of Barcelona, and IDIBAPS, Barcelona, Spain.; European Foundation for the Study of Chronic Liver Failure (EF-CLIF), Barcelona, Spain., Romero-Gómez M; Hospital Universitario Virgen del Rocío de Sevilla, Sevilla, Spain.; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Instituto de Biomedicina de Sevilla (IBIS), Sevilla, Spain.; University of Sevilla, Sevilla, Spain.; Digestive Diseases Unit, Virgen del Rocio University Hospital, Institute of Biomedicine of Seville, University of Seville, Seville, Spain., Albillos A; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Gastroenterology, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS), University of Alcalá, Madrid, Spain., Invernizzi P; European Reference Network on Hepatological Diseases (ERN RARE-LIVER), San Gerardo Hospital, Monza, Italy.; Division of Gastroenterology, School of Medicine and Surgery, Center for Autoimmune Liver Diseases, University of Milano-Bicocca, Milan, Italy., Buti M; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Liver Unit, Department of Internal Medicine, Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain.; Universitat Autònoma de Barcelona, Bellatera, Spain., Duga S; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., Bujanda L; Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBEREHD), Instituto de Salud Carlos III (ISCIII), Madrid, Spain.; Department of Liver and Gastrointestinal Diseases, Biodonostia Health Research Institute-Donostia University Hospital, University of the Basque Country (UPV/EHU), CIBERehd, Ikerbasque, San Sebastian, Spain., Hov JR; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Department of Transplantation Medicine, Norwegian PSC Research Center, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Division for Cancer Medicine, Surgery and Transplantation, Section for Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Lenz TL; Research Group for Evolutionary Immunogenomics, Max Planck Institute for Evolutionary Biology, Plön, Germany.; Research Unit for Evolutionary Immunogenomics, Department of Biology, University of Hamburg, Hamburg, Germany., Asselta R; IRCCS Humanitas Research Hospital, Milan, Italy.; Department of Biomedical Sciences, Humanitas University, Milan, Italy., de Cid R; Genomes for Life-GCAT Lab, Germans Trias i Pujol Research Institute (IGTP), Badalona, Spain., Valenti L; University of Milan, Milan, Italy.; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Karlsen TH; Institute of Clinical Medicine, University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Research Institute for Internal Medicine, Oslo University Hospital Rikshospitalet and University of Oslo, Oslo, Norway.; Division of Surgery, Inflammatory Diseases and Transplantation, Department of Transplantation Medicine, Norwegian PSC Research Center, Oslo University Hospital Rikshospitalet, Oslo, Norway.; Division for Cancer Medicine, Surgery and Transplantation, Section for Gastroenterology, Department of Transplantation Medicine, Oslo University Hospital Rikshospitalet, Oslo, Norway., Cáceres M; Institut de Biotecnologia i de Biomedicina, Universitat Autònoma de Barcelona, Barcelona, Spain.; ICREA, Barcelona, Spain., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University, Kiel, Germany.; University Hospital Schleswig-Holstein (UKSH), Kiel, Germany.

Publikováno v: Human molecular genetics [Hum Mol Genet] 2022 Nov 28; Vol. 31 (23), pp. 3945-3966.

Elevated plasma levels of epithelial and endothelial cell markers in COVID-19 survivors with reduced lung diffusing capacity six months after hospital discharge.

Autor: Sibila O; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain. osibila@clinic.cat.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain. osibila@clinic.cat.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain. osibila@clinic.cat., Perea L; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Albacar N; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Moisés J; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Cruz T; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Mendoza N; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Solarat B; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Lledó G; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Autoimmune Diseases Department, IDIBAPS, University of Barcelona, Hospital Clínic, Barcelona, Spain., Espinosa G; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Autoimmune Diseases Department, IDIBAPS, University of Barcelona, Hospital Clínic, Barcelona, Spain., Barberà JA; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Badia JR; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Agustí A; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Sellarés J; Pulmonary Service, Respiratory Institute, Hospital Clínic, University of Barcelona, C/Villaroel 170, 08036, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain., Faner R; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), C/Roselló 149, 08036, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (CIBER), Barcelona, Spain.

Publikováno v: Respiratory research [Respir Res] 2022 Feb 21; Vol. 23 (1), pp. 37. Date of Electronic Publication: 2022 Feb 21.

Once-daily 1 g ceftriaxone optimizes exposure in patients with septic shock and hypoalbuminemia receiving continuous veno-venous hemodiafiltration.

Autor: Ulldemolins M; Infectious Diseases - Internal Medicine Departments, Bellvitge University Hospital, University of Barcelona, L'Hopspitalet de Llobregat, Spain. marta.ulldemolins@gmail.com., Bastida C; Pharmacy Department, Division of Medicines, Hospital Clinic de Barcelona, Barcelona, Spain., Llauradó-Serra M; Department of Nursing, School of Medicine and Health Sciences, Universitat Internacional de Catalunya, Barcelona, Spain., Csajka C; Service of Clinical Pharmacology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.; School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland., Rodríguez A; Critical Care Department, Joan XXIII University Hospital, Institut d'Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira I Virgili, Tarragona, Spain.; Centro de Investigación Biomédica En Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Badia JR; Centro de Investigación Biomédica En Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Respiratory Intensive Care Unit, Hospital Clínic de Barcelona, Barcelona, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain., Martín-Loeches I; Centro de Investigación Biomédica En Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Multidisciplinary Intensive Care Research Organization (MICRO), Critical Care Department, St James University Hospital, Trinity Centre for Health Sciences, Dublin, Ireland., Soy D; Pharmacy Department, Division of Medicines, Hospital Clinic de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica En Red de Enfermedades Respiratorias (CIBERES), Madrid, Spain.; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS) - Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.

Publikováno v: European journal of clinical pharmacology [Eur J Clin Pharmacol] 2021 Aug; Vol. 77 (8), pp. 1169-1180. Date of Electronic Publication: 2021 Feb 09.

Role of respiratory intermediate care units during the SARS-CoV-2 pandemic.

Autor: Matute-Villacís M; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain., Moisés J; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Embid C; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Armas J; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain., Fernández I; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain., Medina M; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain., Ferrer M; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Sibila O; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain., Badia JR; Servei de Pneumologia i Al·lèrgia Respiratòria, Institut Clínic Respiratori, Hospital Clínic de Barcelona, Universitat de Barcelona, IDIBAPS, Barcelona, Spain. jrbadia@clinic.cat.; CIBER de Enfermedades Respiratorias (CIBERES), Madrid, Spain. jrbadia@clinic.cat.

Publikováno v: BMC pulmonary medicine [BMC Pulm Med] 2021 Jul 13; Vol. 21 (1), pp. 228. Date of Electronic Publication: 2021 Jul 13.