Tissue engineering and regenerative approaches to improving the healing of large bone defects

Autor: S Verrier, M Alini, E Alsberg, SR Buchman, D Kelly, MW Laschke, MD Menger, WL Murphy, JP Stegemann, M Schütz, T Miclau, MJ Stoddart, C Evans

Publikováno v: European Cells & Materials, Vol 32, Pp 87-110 (2016)

Despite the high innate regenerative capacity of bone, large osseous defects fail to heal and remain a clinical challenge. Healing such defects requires the formation of large amounts of bone in an environment often rendered hostile to osteogenesis b

Externí odkaz: https://doaj.org/article/54450140904c44d393bf902c4265c446

Clinical Outcome and 7-Day Virological Clearance in High-Risk Patients with Mild–Moderate COVID-19 Treated with Molnupiravir, Nirmatrelvir/Ritonavir, or Remdesivir.

Autor: Bai, Francesca¹ (AUTHOR) francesca.bai@asst-santipaolocarlo.it, Beringheli, Tomaso¹ (AUTHOR), Vitaletti, Virginia¹ (AUTHOR), Santoro, Andrea¹ (AUTHOR), Molà, Francesco¹ (AUTHOR), Copes, Alessandro¹ (AUTHOR), Gemignani, Nicole¹ (AUTHOR), Pettenuzzo, Sofia¹ (AUTHOR), Castoldi, Roberto¹ (AUTHOR), Varisco, Benedetta¹ (AUTHOR), Nardo, Riccardo¹ (AUTHOR), Lundgren, Lorenzo Brando¹ (AUTHOR), Ligresti, Riccardo¹ (AUTHOR), Sala, Matteo¹ (AUTHOR), Albertini, Lorenzo¹ (AUTHOR), Augello, Matteo¹ (AUTHOR), Biasioli, Lorenzo¹ (AUTHOR), Bono, Valeria¹ (AUTHOR), Rovito, Roberta¹ (AUTHOR), Bini, Teresa¹ (AUTHOR)

Publikováno v: Infectious Diseases & Therapy. Jul2024, Vol. 13 Issue 7, p1589-1605. 17p.

Efficacy of Tocilizumab in Severely Ill COVID-19 Patients With Rapid Respiratory Deterioration: A Single Center Experience During the Third Pandemic Wave in Greece.

Autor: RAPTI, VASILIKI, LIVANOU, MARIA-EFFROSYNI, KOLLIAS, ANASTASIOS, KOUTOURATSAS, TILEMACHOS, SAVRANAKIS, ORESTIS, SAKKA, VISSARIA, NITSOTOLIS, THOMAS, KAKALOU, ELENI, ATHANASIOU, KALOMOIRA, SYRIGOS, KONSTANTINOS N., POULAKOU, GARYFALLIA

Publikováno v: In Vivo; May/Jun2023, Vol. 37 Issue 3, p1312-1317, 6p

Small-molecule anti-COVID-19 drugs and a focus on China's homegrown mindeudesivir (VV116).

Autor: Cao Q; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Ding Y; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Xu Y; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Li M; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Zheng R; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Cao Z; Department of Infectious Disease, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Wang W; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Bi Y; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Ning G; Department of Endocrine and Metabolic Diseases, Shanghai Institute of Endocrine and Metabolic Diseases, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.; Shanghai National Clinical Research Center for Metabolic Diseases, State Key Laboratory of Medical Genomics, Key Laboratory for Endocrine and Metabolic Diseases of the National Health Commission, Shanghai National Center for Translational Medicine, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China., Xu Y; Clinical Trials Center, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. xyp30363@rjh.com.cn., Zhao R; Department of General Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China. zhaorensurgeon@aliyun.com.

Publikováno v: Frontiers of medicine [Front Med] 2023 Dec; Vol. 17 (6), pp. 1068-1079. Date of Electronic Publication: 2024 Jan 02.

Cardiovascular disease and COVID-19: a consensus paper from the ESC Working Group on Coronary Pathophysiology & Microcirculation, ESC Working Group on Thrombosis and the Association for Acute CardioVascular Care (ACVC), in collaboration with the European Heart Rhythm Association (EHRA)

Autor: Cenko, Edina, Badimon, Lina, Bugiardini, Raffaele, Claeys, Marc J, Luca, Giuseppe De, Wit, Cor de, Derumeaux, Geneviève, Dorobantu, Maria, Duncker, Dirk J, Eringa, Etto C, Gorog, Diana A, Hassager, Christian, Heinzel, Frank R, Huber, Kurt, Manfrini, Olivia, Milicic, Davor, Oikonomou, Evangelos, Padro, Teresa, Trifunovic-Zamaklar, Danijela, Vasiljevic-Pokrajcic, Zorana

Publikováno v: Cardiovascular Research; Dec2021, Vol. 117 Issue 14, p2705-2729, 25p