Zobrazeno 1 - 10
of 38
pro vyhledávání: '"JP Schoeller"'
Publikováno v:
Journal of Pharmaceutical Sciences. 69:1413-1416
Plasma concentration profiles were studied after single and oral doses of phenylbutazone of 100, 300, and 600 mg in cachets to six healthy volunteers. The pharmacokinetics of phenylbutazone can be described by a two-compartment open model. The drug i
Autor:
J Hirtz, N. Vidon, D Evard, Jean-Jacques Bernier, JP Schoeller, M. Rongier, M Duval, J. Godbillon
Publikováno v:
British Journal of Clinical Pharmacology. 19:107S-112S
Absorption of metoprolol in jejunum and ileum was investigated in eight healthy subjects using an intestinal perfusion technique below an occlusive balloon. An isotonic saline solution, with or without metoprolol, was perfused at a flow rate of 10 ml
Publikováno v:
British Journal of Clinical Pharmacology. 19:113S-118S
The colonic absorption of metoprolol was indirectly evaluated by measuring drug appearance in plasma following intravenous, jejunal or colonic infusion in six healthy volunteers. Plasma concentrations of alpha-hydroxymetoprolol and urinary excretion
Autor:
A. Cortot, J. Godbillon, JP Schoeller, Jean-Jacques Bernier, J Hirtz, G. Jobin, E. Danquechin-Dorval
Publikováno v:
British Journal of Clinical Pharmacology. 19:127S-135S
The role of the adrenergic system in normal gastric function was assessed in five healthy volunteers by measuring gastric secretion and emptying after a mixed meal containing a non-absorbable marker, [14C]-PEG 4000, with and without 100 mg of metopro
Publikováno v:
British Journal of Clinical Pharmacology. 19:245S-249S
The influence of food on the release, absorption and metabolism of metoprolol has been studied after single administration of a 19/190 Oros system to eight healthy volunteers on four occasions, once after an overnight fast, and just before each of th
Autor:
F Leroux, M Olivier-Martin, JP Schoeller, D Hillion, Antoine Sioufi, R Wainer, P. Mangoni, D. Colussi, P Lumbroso
Publikováno v:
British journal of clinical pharmacology. 18(3)
Thirty-two pregnant hypertensive patients were treated with oxprenolol administered in combination with dihydralazine as Trasipressol tablets. Before delivery, oxprenolol was demonstrable in the maternal plasma and the amniotic fluid. The free fracti
Autor:
M Bovet, Jean-Jacques Bernier, N. Vidon, J. Godbillon, JP Schoeller, D Evard, M Duval, J Hirtz
Publikováno v:
British journal of clinical pharmacology. 19
The influence of nutrients and digestive secretions on the intestinal absorption and bioavailability of the beta-adrenoceptor antagonist, metoprolol, was investigated in an isolated segment of jejunum using an intestinal perfusion technique. Two solu
Publikováno v:
British journal of clinical pharmacology. 16(6)
Gastrointestinal (GI) absorption of the beta-adrenoceptor blocker metoprolol was investigated in five healthy subjects by means of an intubation method, employing a triple-lumen tube introduced into the intestine, and a twin-lumen tube in the stomach
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d67284fe32a510d669a49a80870242f7
https://europepmc.org/articles/PMC1463760/
https://europepmc.org/articles/PMC1463760/
Publikováno v:
Therapie [Therapie] 1983 Jul-Aug; Vol. 38 (4), pp. 431-4.