Zobrazeno 1 - 10
of 146
pro vyhledávání: '"JORGE D. BRIONI"'
Autor:
Masaki Nakane, Teodozyi Kolasa, Renjie Chang, Loan N. Miller, Robert B. Moreland, Jorge D. Brioni
Publikováno v:
Journal of Pharmacological Sciences, Vol 102, Iss 2, Pp 231-238 (2006)
Soluble guanylyl cyclase (sGC) is a target enzyme for endogenous nitric oxide (NO), and it converts GTP to cyclic GMP (guanosine 3’,5’-cyclic monophosphate) as part of a cascade that results in physiological processes such as smooth muscle relaxa
Externí odkaz:
https://doaj.org/article/2c91e13b85a24b508131e6748e404ce8
Publikováno v:
Journal of Anesthesia
A large number of studies during the past two decades have demonstrated the efficacy and safety of sevoflurane across patient populations. Clinical researchers have also investigated the effects of sevoflurane, its hemodynamic characteristics, its po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ac49af3236e643d6c5504257f6a9d4a
http://europepmc.org/articles/PMC5640726
http://europepmc.org/articles/PMC5640726
Publikováno v:
In Japanese Journal of Pharmacology 1999 79(1):59-64
Autor:
Karla Drescher, Jorge D. Brioni, Janel M. Boyce-Rustay, Ana Basso, William Bracken, Timothy A. Esbenshade, Kaitlin E. Browman, James J. Lynch, Lise I. Loberg, Thomas J. Hudzik
Publikováno v:
Psychopharmacology. 228:187-197
Histamine H3 receptor antagonists, such as ABT-288, have been shown to possess cognitive-enhancing and wakefulness-promoting effects. On the surface, this might suggest that H3 antagonists possess psychomotor stimulant-like effects and, as such, may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24f94874484f339be3d3e720a560e27b
https://doi.org/10.1007/s00213-013-3027-7
https://doi.org/10.1007/s00213-013-3027-7
Autor:
Jorge D. Brioni, Tracy L. Carr, Gin C. Hsieh, Madhavi Pai, Lawrence A. Black, Tiffany Runyan Garrison, Cenchen Zhan, Marlon D. Cowart, Erica Gomez, Gilbert Diaz, Arlene M. Manelli, Marina I. Strakhova, Anthony Lee, Jill M. Wetter
Publikováno v:
European Journal of Pharmacology. 684:87-94
Histamine H(3) receptor antagonists have been widely reported to improve performance in preclinical models of cognition, but more recently efficacy in pain models has also been described. Here, A-960656 ((R)-2-(2-(3-(piperidin-1-yl)pyrrolidin-1-yl)be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54c0e87b77f27eefbbaad46501b1babe
https://doi.org/10.1016/j.ejphar.2012.03.048
https://doi.org/10.1016/j.ejphar.2012.03.048
Autor:
Tim A. Esbenshade, Jorge D. Brioni, Marlon D. Cowart, Tiffany Runyan Garrison, Scott R. Bitner
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 336:38-46
H(3) antagonists increase the release of brain histamine, acetylcholine, noradrenaline, and dopamine, neurotransmitters that are known to modulate cognitive processes. The ability to release brain histamine supports the effect on attention and vigila
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26d34f3a3a83d110479ed67d6ccd92bb
https://doi.org/10.1124/jpet.110.166876
https://doi.org/10.1124/jpet.110.166876
Autor:
Arthur A. Hancock, Jill M. Wetter, Kennan C. Marsh, Prisca Honore, Gin C. Hsieh, Anita K. Salyers, Prasant Chandran, Timothy A. Esbenshade, Marlon D. Cowart, Joe Mikusa, Jorge D. Brioni, Erica J. Wensink, Madhavi Pai, Thomas R. Miller, Scott J. Baker, Chang Z. Zhu, David G. Witte
Publikováno v:
Pharmacology Biochemistry and Behavior. 95:41-50
The histamine H(4) receptor (H(4)R) is expressed primarily on cells involved in inflammation and immune responses. To determine the potential role of H(4)R in pain transmission, the effects of JNJ7777120, a potent and selective H(4) antagonist, were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3217e8b864839ddd3ab2c66a0d548d8d
https://doi.org/10.1016/j.pbb.2009.12.004
https://doi.org/10.1016/j.pbb.2009.12.004
Autor:
Kennan C. Marsh, Marlon D. Cowart, Jorge D. Brioni, Ivan Milicic, Timothy A. Esbenshade, J Bauch, J Du, Thomas R. Miller, Kaitlin E. Browman, Bruce W. Surber
Publikováno v:
British Journal of Pharmacology. 157:139-149
Background and purpose: The histamine H3 receptor antagonist radioligand [3H]-A-349821 was characterized as a radiotracer for assessing in vivo receptor occupancy by H3 receptor antagonists that affect behaviour. This model was established as an alte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6624285355398049a2bac47290ba815d
https://doi.org/10.1111/j.1476-5381.2009.00239.x
https://doi.org/10.1111/j.1476-5381.2009.00239.x
Autor:
J. L. Baranowski, David G. Witte, RM Adair, K. C. Marsh, Jorge D. Brioni, AM Manelli, Tracy L. Carr, Cowart, H. Liu, Jill M. Wetter, Carolyn A. Cuff, Betty B. Yao, Timothy A. Esbenshade, M. I. Strakhova, TA Vortherms, L Rundell, Auriléia Aparecida de Brito, Thomas R. Miller, Mcpherson Michael J, BM Bettencourt
Publikováno v:
British Journal of Pharmacology. 157:44-54
Background and purpose: The histamine H4 receptor is widely expressed in cells of immune origin and has been shown to play a role in a variety of inflammatory processes mediated by histamine. In this report, we describe the in vitro and in vivo anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4b03928338c4004241fbc453c91f11f2
https://doi.org/10.1111/j.1476-5381.2009.00236.x
https://doi.org/10.1111/j.1476-5381.2009.00236.x
Autor:
Robert S. Bitner, Arlene M. Manelli, Marina I. Strakhova, Jorge D. Brioni, Gin C. Hsieh, Timothy A. Esbenshade, Arthur L. Nikkel
Publikováno v:
Brain Research. 1250:41-48
Existing data on the expression of H(4) histamine receptor in the CNS are conflicting and inconclusive. In this report, we present the results of experiments that were conducted in order to elucidate H(4) receptor expression and localization in the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7959c1cacba3d0770fac34f8b4e0010
https://doi.org/10.1016/j.brainres.2008.11.018
https://doi.org/10.1016/j.brainres.2008.11.018