Zobrazeno 1 - 10
of 13
pro vyhledávání: '"JONATHAN BRADFIELD"'
Autor:
Lindsay Fernández-Rhodes, Mariaelisa Graff, Victoria L. Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo, Wanying Zhu, Hung-Hsin Chen, Kristin L. Young, Kaustubh Adhikari, Nicholette D. Palmer, Jennifer E. Below, Jonathan Bradfield, Alexandre C. Pereira, LáShauntá Glover, Daeeun Kim, Adam G. Lilly, Poojan Shrestha, Alvin G. Thomas, Xinruo Zhang, Minhui Chen, Charleston W.K. Chiang, Sara Pulit, Andrea Horimoto, Jose E. Krieger, Marta Guindo-Martínez, Michael Preuss, Claudia Schumann, Roelof A.J. Smit, Gabriela Torres-Mejía, Victor Acuña-Alonzo, Gabriel Bedoya, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Rolando González-José, Giovanni Poletti, Francisco Rothhammer, Hakon Hakonarson, Robert Igo, Sharon G. Adler, Sudha K. Iyengar, Susanne B. Nicholas, Stephanie M. Gogarten, Carmen R. Isasi, George Papnicolaou, Adrienne M. Stilp, Qibin Qi, Minjung Kho, Jennifer A. Smith, Carl D. Langefeld, Lynne Wagenknecht, Roberta Mckean-Cowdin, Xiaoyi Raymond Gao, Darryl Nousome, David V. Conti, Ye Feng, Matthew A. Allison, Zorayr Arzumanyan, Thomas A. Buchanan, Yii-Der Ida Chen, Pauline M. Genter, Mark O. Goodarzi, Yang Hai, Willa Hsueh, Eli Ipp, Fouad R. Kandeel, Kelvin Lam, Xiaohui Li, Jerry L. Nadler, Leslie J. Raffel, Kathryn Roll, Kevin Sandow, Jingyi Tan, Kent D. Taylor, Anny H. Xiang, Jie Yao, Astride Audirac-Chalifour, Jose de Jesus Peralta Romero, Fernando Hartwig, Bernando Horta, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Donna E. Lehman, Sobha Puppala, Laura Fejerman, Esther M. John, Carlos Aguilar-Salinas, Noël P. Burtt, Jose C. Florez, Humberto García-Ortíz, Clicerio González-Villalpando, Josep Mercader, Lorena Orozco, Teresa Tusié-Luna, Estela Blanco, Sheila Gahagan, Nancy J. Cox, Craig Hanis, Nancy F. Butte, Shelley A. Cole, Anthony G. Comuzzie, V. Saroja Voruganti, Rebecca Rohde, Yujie Wang, Tamar Sofer, Elad Ziv, Struan F.A. Grant, Andres Ruiz-Linares, Jerome I. Rotter, Christopher A. Haiman, Esteban J. Parra, Miguel Cruz, Ruth J.F. Loos, Kari E. North
Publikováno v:
HGG Advances, Vol 4, Iss 1, Pp 100149- (2023)
Externí odkaz:
https://doaj.org/article/0972e4eb8a0442ae9963f4515576db6a
Autor:
Hui-Qi Qu, Jingchun Qu, Jonathan Bradfield, Luc Marchand, Joseph Glessner, Xiao Chang, Michael March, Jin Li, John J. Connolly, Jeffrey D. Roizen, Patrick Sleiman, Constantin Polychronakos, Hakon Hakonarson
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-10 (2021)
Hui-Qi Qu et al. present a case-control association study to examine the genetic architecture of European patients with type 1 diabetes (T1D) of low genetic risk score. They identify 41 loci associated with T1D of low genetic risk score, including re
Externí odkaz:
https://doaj.org/article/299624c58fdb434482bd26884aea79ed
Autor:
Lindsay Fernández-Rhodes, Mariaelisa Graff, Victoria L. Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo, Wanying Zhu, Hung-Hsin Chen, Kristin L. Young, Kaustubh Adhikari, Nicholette D. Palmer, Jennifer E. Below, Jonathan Bradfield, Alexandre C. Pereira, LáShauntá Glover, Daeeun Kim, Adam G. Lilly, Poojan Shrestha, Alvin G. Thomas, Xinruo Zhang, Minhui Chen, Charleston W.K. Chiang, Sara Pulit, Andrea Horimoto, Jose E. Krieger, Marta Guindo-Martínez, Michael Preuss, Claudia Schumann, Roelof A.J. Smit, Gabriela Torres-Mejía, Victor Acuña-Alonzo, Gabriel Bedoya, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Rolando González-José, Giovanni Poletti, Francisco Rothhammer, Hakon Hakonarson, Robert Igo, Sharon G. Adler, Sudha K. Iyengar, Susanne B. Nicholas, Stephanie M. Gogarten, Carmen R. Isasi, George Papnicolaou, Adrienne M. Stilp, Qibin Qi, Minjung Kho, Jennifer A. Smith, Carl D. Langefeld, Lynne Wagenknecht, Roberta Mckean-Cowdin, Xiaoyi Raymond Gao, Darryl Nousome, David V. Conti, Ye Feng, Matthew A. Allison, Zorayr Arzumanyan, Thomas A. Buchanan, Yii-Der Ida Chen, Pauline M. Genter, Mark O. Goodarzi, Yang Hai, Willa Hsueh, Eli Ipp, Fouad R. Kandeel, Kelvin Lam, Xiaohui Li, Jerry L. Nadler, Leslie J. Raffel, Kathryn Roll, Kevin Sandow, Jingyi Tan, Kent D. Taylor, Anny H. Xiang, Jie Yao, Astride Audirac-Chalifour, Jose de Jesus Peralta Romero, Fernando Hartwig, Bernando Horta, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Donna E. Lehman, Sobha Puppala, Laura Fejerman, Esther M. John, Carlos Aguilar-Salinas, Noël P. Burtt, Jose C. Florez, Humberto García-Ortíz, Clicerio González-Villalpando, Josep Mercader, Lorena Orozco, Teresa Tusié-Luna, Estela Blanco, Sheila Gahagan, Nancy J. Cox, Craig Hanis, Nancy F. Butte, Shelley A. Cole, Anthony G. Comuzzie, V. Saroja Voruganti, Rebecca Rohde, Yujie Wang, Tamar Sofer, Elad Ziv, Struan F.A. Grant, Andres Ruiz-Linares, Jerome I. Rotter, Christopher A. Haiman, Esteban J. Parra, Miguel Cruz, Ruth J.F. Loos, Kari E. North
Publikováno v:
HGG Advances, Vol 3, Iss 2, Pp 100099- (2022)
Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and overweight/obesity. To addr
Externí odkaz:
https://doaj.org/article/15abb0171a3441e4bc460a26e6cdd18c
Autor:
Yun Rose Li, Joseph T. Glessner, Bradley P. Coe, Jin Li, Maede Mohebnasab, Xiao Chang, John Connolly, Charlly Kao, Zhi Wei, Jonathan Bradfield, Cecilia Kim, Cuiping Hou, Munir Khan, Frank Mentch, Haijun Qiu, Marina Bakay, Christopher Cardinale, Maria Lemma, Debra Abrams, Andrew Bridglall-Jhingoor, Meckenzie Behr, Shanell Harrison, George Otieno, Alexandria Thomas, Fengxiang Wang, Rosetta Chiavacci, Lawrence Wu, Dexter Hadley, Elizabeth Goldmuntz, Josephine Elia, John Maris, Robert Grundmeier, Marcella Devoto, Brendan Keating, Michael March, Renata Pellagrino, Struan F. A. Grant, Patrick M. A. Sleiman, Mingyao Li, Evan E. Eichler, Hakon Hakonarson
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-9 (2020)
Associations of copy number variations (CNVs) with complex traits are challenging to study because of their low frequency. Here, the authors analyse SNP array and array comparative genomic hybridization data of 100,028 individuals and report their as
Externí odkaz:
https://doaj.org/article/bff05ccd6ca145f18966c6e073fcf8bb
Autor:
Jason D Christie, Mark M Wurfel, Rui Feng, Grant E O'Keefe, Jonathan Bradfield, Lorraine B Ware, David C Christiani, Carolyn S Calfee, Mitchell J Cohen, Michael Matthay, Nuala J Meyer, Cecilia Kim, Mingyao Li, Joshua Akey, Kathleen C Barnes, Jonathan Sevransky, Paul N Lanken, Addison K May, Richard Aplenc, James P Maloney, Hakon Hakonarson, Trauma ALI SNP Consortium (TASC) investigators
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28268 (2012)
Acute Lung Injury (ALI) is a syndrome with high associated mortality characterized by severe hypoxemia and pulmonary infiltrates in patients with critical illness. We conducted the first investigation to use the genome wide association (GWA) approach
Externí odkaz:
https://doaj.org/article/53bd74564aec407da58a5e14822a342b
Autor:
Zhi Wei, Kai Wang, Hui-Qi Qu, Haitao Zhang, Jonathan Bradfield, Cecilia Kim, Edward Frackleton, Cuiping Hou, Joseph T Glessner, Rosetta Chiavacci, Charles Stanley, Dimitri Monos, Struan F A Grant, Constantin Polychronakos, Hakon Hakonarson
Publikováno v:
PLoS Genetics, Vol 5, Iss 10, p e1000678 (2009)
Genome-wide association studies (GWAS) have been fruitful in identifying disease susceptibility loci for common and complex diseases. A remaining question is whether we can quantify individual disease risk based on genotype data, in order to facilita
Externí odkaz:
https://doaj.org/article/5ac29935a4e84924af06b44d74f45310
Autor:
Louise C. Pyle, Jung Kim, Jonathan Bradfield, Scott M. Damrauer, Kurt D'Andrea, Lawrence H. Einhorn, Rama Godse, Hakon Hakonarson, Peter A. Kanetsky, Rachel L. Kember, Linda A. Jacobs, Kara N. Maxwell, Daniel J. Rader, David J. Vaughn, Benita Weathers, Bradley Wubbenhorst, null Regeneron Genetics Center Research Team, null Cancer Genomics Research Laboratory, Mark H. Greene, Katherine L. Nathanson, Douglas R. Stewart
Publikováno v:
European Urology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f08de52b731ff592a8f26929a5c61edb
https://doi.org/10.1016/j.eururo.2023.05.008
https://doi.org/10.1016/j.eururo.2023.05.008
Autor:
SHERIDAN H. LITTLETON, JONATHAN BRADFIELD, JAMES A. PIPPIN, CHUN SU, ALESSANDRA CHESI, ANDREW D. WELLS, ROBERT I. BERKOWITZ, MATTHEW C. PAHL, STRUAN F. GRANT
Publikováno v:
Diabetes. 71
A key limitation of genome-wide association studies (GWAS) is that they do not specify either the underlying causal variant (s) or the effector gene (s) at a given locus. The widely reproduced obesity FAIM2 locus, named arbitrarily after the nearest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dc2e5c6c081e7762f49a31ce022e488c
https://doi.org/10.2337/db22-298-or
https://doi.org/10.2337/db22-298-or
Autor:
Lindsay Fernández-Rhodes, Mariaelisa Graff, Victoria L. Buchanan, Anne E. Justice, Heather M. Highland, Xiuqing Guo, Wanying Zhu, Hung-Hsin Chen, Kristin L. Young, Kaustubh Adhikari, Nicholette D. Palmer, Jennifer E. Below, Jonathan Bradfield, Alexandre C. Pereira, LáShauntá Glover, Daeeun Kim, Adam G. Lilly, Poojan Shrestha, Alvin G. Thomas, Xinruo Zhang, Minhui Chen, Charleston W.K. Chiang, Sara Pulit, Andrea Horimoto, Jose E. Krieger, Marta Guindo-Martínez, Michael Preuss, Claudia Schumann, Roelof A.J. Smit, Gabriela Torres-Mejía, Victor Acuña-Alonzo, Gabriel Bedoya, Maria-Cátira Bortolini, Samuel Canizales-Quinteros, Carla Gallo, Rolando González-José, Giovanni Poletti, Francisco Rothhammer, Hakon Hakonarson, Robert Igo, Sharon G. Adler, Sudha K. Iyengar, Susanne B. Nicholas, Stephanie M. Gogarten, Carmen R. Isasi, George Papnicolaou, Adrienne M. Stilp, Qibin Qi, Minjung Kho, Jennifer A. Smith, Carl D. Langefeld, Lynne Wagenknecht, Roberta Mckean-Cowdin, Xiaoyi Raymond Gao, Darryl Nousome, David V. Conti, Ye Feng, Matthew A. Allison, Zorayr Arzumanyan, Thomas A. Buchanan, Yii-Der Ida Chen, Pauline M. Genter, Mark O. Goodarzi, Yang Hai, Willa Hsueh, Eli Ipp, Fouad R. Kandeel, Kelvin Lam, Xiaohui Li, Jerry L. Nadler, Leslie J. Raffel, Kathryn Roll, Kevin Sandow, Jingyi Tan, Kent D. Taylor, Anny H. Xiang, Jie Yao, Astride Audirac-Chalifour, Jose de Jesus Peralta Romero, Fernando Hartwig, Bernando Horta, John Blangero, Joanne E. Curran, Ravindranath Duggirala, Donna E. Lehman, Sobha Puppala, Laura Fejerman, Esther M. John, Carlos Aguilar-Salinas, Noël P. Burtt, Jose C. Florez, Humberto García-Ortíz, Clicerio González-Villalpando, Josep Mercader, Lorena Orozco, Teresa Tusié-Luna, Estela Blanco, Sheila Gahagan, Nancy J. Cox, Craig Hanis, Nancy F. Butte, Shelley A. Cole, Anthony G. Comuzzie, V. Saroja Voruganti, Rebecca Rohde, Yujie Wang, Tamar Sofer, Elad Ziv, Struan F.A. Grant, Andres Ruiz-Linares, Jerome I. Rotter, Christopher A. Haiman, Esteban J. Parra, Miguel Cruz, Ruth J.F. Loos, Kari E. North
Publikováno v:
Fernández-Rhodes, L, Graff, M, Buchanan, V L, Justice, A E, Highland, H M, Guo, X, Zhu, W, Chen, H H, Young, K L, Adhikari, K, Palmer, N D, Below, J E, Bradfield, J, Pereira, A C, Glover, L S, Kim, D, Lilly, A G, Shrestha, P, Thomas, A G, Zhang, X, Chen, M, Chiang, C W K, Pulit, S, Horimoto, A, Krieger, J E, Guindo-Martínez, M, Preuss, M, Schumann, C, Smit, R A J, Torres-Mejía, G, Acuña-Alonzo, V, Bedoya, G, Bortolini, M C, Canizales-Quinteros, S, Gallo, C, González-José, R, Poletti, G, Rothhammer, F, Hakonarson, H, Igo, R, Adler, S G, Iyengar, S K, Nicholas, S B, Gogarten, S M, Isasi, C R, Papnicolaou, G, Stilp, A M, Qi, Q, Kho, M, Smith, J A, Langefeld, C D, Wagenknecht, L, Mckean-Cowdin, R, Gao, X R, Nousome, D, Conti, D V, Feng, Y, Allison, M A, Arzumanyan, Z, Buchanan, T A, Ida Chen, Y D, Genter, P M, Goodarzi, M O, Hai, Y, Hsueh, W, Ipp, E, Kandeel, F R, Lam, K, Li, X, Nadler, J L, Raffel, L J, Roll, K, Sandow, K, Tan, J, Taylor, K D, Xiang, A H, Yao, J, Audirac-Chalifour, A, de Jesus Peralta Romero, J, Hartwig, F, Horta, B, Blangero, J, Curran, J E, Duggirala, R, Lehman, D E, Puppala, S, Fejerman, L, John, E M, Aguilar-Salinas, C, Burtt, N P, Florez, J C, García-Ortíz, H, González-Villalpando, C, Mercader, J, Orozco, L, Tusié-Luna, T, Blanco, E, Gahagan, S, Cox, N J, Hanis, C, Butte, N F, Cole, S A, Comuzzie, A G, Voruganti, V S, Rohde, R, Wang, Y, Sofer, T, Ziv, E, Grant, S F A, Ruiz-Linares, A, Rotter, J I, Haiman, C A, Parra, E J, Cruz, M, Loos, R J F & North, K E 2022, ' Ancestral diversity improves discovery and fine-mapping of genetic loci for anthropometric traits—The Hispanic/Latino Anthropometry Consortium ', Human Genetics and Genomics Advances, vol. 3, no. 2, 100099 . https://doi.org/10.1016/j.xhgg.2022.100099
HGG Adv
HGG Adv
Hispanic/Latinos have been underrepresented in genome-wide association studies (GWAS) for anthropometric traits despite their notable anthropometric variability, ancestry proportions, and high burden of growth stunting and overweight/obesity. To addr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::30555898f9dbdfd782d794877e283a19
https://pubmed.ncbi.nlm.nih.gov/36268164
https://pubmed.ncbi.nlm.nih.gov/36268164
Autor:
Leah Ragno, Daphne Yang, Trisha Bhatti, Jonathan Bradfield, Diane Bowen, Katheryn Grand, Hakon Hakonarson, Thomas Kolon, Joseph Glessner, M. Celeste Simon, Nicolas Skuli, Maria Vogiatzi, Marie Guerraty, Matthew Deardorff, Louisa Pyle
Publikováno v:
Genetics in Medicine. 24:S137-S138
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69bd98bb18f4642175175d983ef3fab6
https://doi.org/10.1016/j.gim.2022.01.257
https://doi.org/10.1016/j.gim.2022.01.257