Zobrazeno 1 - 10
of 61
pro vyhledávání: '"JON GRIFFIN"'
Autor:
Jon Griffin, Jenny Down, Lewis A Quayle, Paul R Heath, Ewan A Gibb, Elai Davicioni, Yang Liu, Xin Zhao, Jayne Swain, Dennis Wang, Syed Hussain, Simon Crabb, James WF Catto, the GUSTO Trial Management Group
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 10, Iss 2, Pp n/a-n/a (2024)
Abstract The GUSTO clinical trial (Gene expression subtypes of Urothelial carcinoma: Stratified Treatment and Oncological outcomes) uses molecular subtypes to guide neoadjuvant therapies in participants with muscle‐invasive bladder cancer (MIBC). B
Externí odkaz:
https://doaj.org/article/4fef0e3838804e81a865003240a3ce8e
Autor:
Jon Griffin
Publikováno v:
Rural and Remote Health, Vol 23 (2023)
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Externí odkaz:
https://doaj.org/article/fc10200afa494d8e93aa2d17f3b317b1
Autor:
Shaliny Ramachandran, Tiffany S. Ma, Jon Griffin, Natalie Ng, Iosifina P. Foskolou, Ming-Shih Hwang, Pedro Victori, Wei-Chen Cheng, Francesca M. Buffa, Katarzyna B. Leszczynska, Sherif F. El-Khamisy, Natalia Gromak, Ester M. Hammond
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Hypoxia induces a change in transcriptional response in mammalian cells. Here the authors reveal a role for the RNA/DNA helicase Senataxin in protecting cells from DNA damage induced during transcription in hypoxia.
Externí odkaz:
https://doaj.org/article/53d171bea0d243d0a270df932d095042
Autor:
Alexandra Rayson, Maya Boudiffa, Maneeha Naveed, Jon Griffin, Enrico Dall’Ara, Ilaria Bellantuono
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Osteoporosis and osteoarthritis are the most common age-related diseases of the musculoskeletal system. They are responsible for high level of healthcare use and are often associated with comorbidities. Mechanisms of ageing such as senescence, inflam
Externí odkaz:
https://doaj.org/article/8f696f0c4e354d7a98d666d136e29649
Autor:
Oliver Reed, Ibrahim Jubber, Jon Griffin, Aidan P Noon, Louise Goodwin, Syed Hussain, Marcus G Cumberbatch, James W F Catto
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0239338 (2020)
ObjectivesUp to 10% of Bladder Cancers may arise following occupational exposure to carcinogens. We hypothesised that different cancer phenotypes reflected different patterns of occupational exposure.MethodsConsecutive participants, with bladder canc
Externí odkaz:
https://doaj.org/article/915d7f21a1be4f5a818267ee19d14c2c
Autor:
Yee Mon Thu, Susan Kaye Van Riper, LeeAnn Higgins, Tianji Zhang, Jordan Robert Becker, Todd William Markowski, Hai Dang Nguyen, Timothy Jon Griffin, Anja Katrin Bielinsky
Publikováno v:
Cell Reports, Vol 15, Iss 6, Pp 1254-1265 (2016)
Loss of minichromosome maintenance protein 10 (Mcm10) causes replication stress. We uncovered that S. cerevisiae mcm10-1 mutants rely on the E3 SUMO ligase Mms21 and the SUMO-targeted ubiquitin ligase complex Slx5/8 for survival. Using quantitative m
Externí odkaz:
https://doaj.org/article/1108d29655574124884429b3b822a107
Publikováno v:
BMJ Case Reports. 16:e252351
Acute renal haemorrhage is a life-threatening condition that is complicated in the context of renal malignancy. Here, we present the case of a teenage male presenting acutely with a large, bleeding renal epithelioid angiomyolipoma (EAML) of the kidne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3ad3c572e4a410a9607efe6a783fbb8
https://doi.org/10.1136/bcr-2022-252351
https://doi.org/10.1136/bcr-2022-252351
Autor:
Priya Patel, Areej Alghamdi, Gary Shaw, Christopher Legge, Maggie Glover, Danielle Freeman, Harry Hodgetts, Erica Wilson, Faith Howard, Sarah Staniland, Aneurin J Kennerley, Duncan Wood, Robert Moorehead, Charlotte Hadfield, Ola Rominiyi, Jon Griffin, Spencer J Collis, Sam Hyde, Marcus Crossley, Martyn Paley, Munitta Muthana
Publikováno v:
Nanotheranostics. 7(1)
Delivering therapies to deeply seated brain tumours (BT) is a major clinical challenge. Magnetic drug targeting (MDT) could overcome this by rapidly transporting magnetised drugs directly into BT. We have developed a magnetic device for application i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9230826cb65ef22f7d4c3aa3b4a6039d
https://pubmed.ncbi.nlm.nih.gov/36593801
https://pubmed.ncbi.nlm.nih.gov/36593801
Autor:
MINNA B. OLSEN, ULRIKE HÖVELMANN, JON GRIFFIN, KIM M. KNUDSEN, PER-OLOF ERIKSSON, MIKKEL A. AGERSNAP
Publikováno v:
Diabetes. 71
Dapiglutide is a first-in-class peptide with dual activity on the GLP-1 and GLP-2 receptors and with potential to treat several metabolic/gastrointestinal (GI) diseases. In a multiple ascending dose cohort trial, 40 healthy subjects (mean BMI 24.6 kg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c46bda5cf93a8951df83bda5423262dc
https://doi.org/10.2337/db22-335-or
https://doi.org/10.2337/db22-335-or
Autor:
Samantha Conroy, Rachel Hubbard, Aidan P. Noon, Syed A. Hussain, Jon Griffin, Steven Kennish, James W. F. Catto
Publikováno v:
BJU international. 129(6)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f983e40d7090fc9c1abc41cc3eaf1c
https://pubmed.ncbi.nlm.nih.gov/35633131
https://pubmed.ncbi.nlm.nih.gov/35633131