Zobrazeno 1 - 10
of 318
pro vyhledávání: '"JOHN W. NEWMAN"'
Autor:
Nuanyi Liang, Kwangsik Nho, John W. Newman, Matthias Arnold, Kevin Huynh, Peter J. Meikle, Kamil Borkowski, Rima Kaddurah-Daouk, the Alzheimer’s Disease Metabolomics Consortium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Inflammation is an important factor in Alzheimer’s disease (AD). An NMR measurement in plasma, glycoprotein acetyls (GlycA), captures the overall level of protein production and glycosylation implicated in systemic inflammation. With its a
Externí odkaz:
https://doaj.org/article/1fa1238cbe3847c59f63509c071de317
Autor:
Sook Wah Yee, Luis Ferrández-Peral, Pol Alentorn-Moron, Claudia Fontsere, Merve Ceylan, Megan L. Koleske, Niklas Handin, Virginia M. Artegoitia, Giovanni Lara, Huan-Chieh Chien, Xujia Zhou, Jacques Dainat, Arthur Zalevsky, Andrej Sali, Colin M. Brand, Finn D. Wolfreys, Jia Yang, Jason E. Gestwicki, John A. Capra, Per Artursson, John W. Newman, Tomàs Marquès-Bonet, Kathleen M. Giacomini
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract SLC22A10 is an orphan transporter with unknown substrates and function. The goal of this study is to elucidate its substrate specificity and functional characteristics. In contrast to orthologs from great apes, human SLC22A10, tagged with gr
Externí odkaz:
https://doaj.org/article/a48ee6cda4514840ac818713e505c1b2
Publikováno v:
Frontiers in Plant Science, Vol 15 (2024)
Tree nut consumption has been widely associated with various health benefits, with walnuts, in particular, being linked with improved cardiovascular and neurological health. These benefits have been attributed to walnuts’ vast array of phenolic ant
Externí odkaz:
https://doaj.org/article/54497ebd27584bceb497a70cc7a1d468
Autor:
Kamil Borkowski, Nicholas T. Seyfried, Matthias Arnold, James J. Lah, Allan I. Levey, Chadwick M. Hales, Eric B. Dammer, Colette Blach, Gregory Louie, Rima Kaddurah-Daouk, John W. Newman
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-13 (2023)
Abstract Integration of the omics data, including metabolomics and proteomics, provides a unique opportunity to search for new associations within metabolic disorders, including Alzheimer’s disease. Using metabolomics, we have previously profiled o
Externí odkaz:
https://doaj.org/article/8bf68a11806b4e5a948a71379d7cd203
Autor:
Poonamjot Deol, Paul Ruegger, Geoffrey D. Logan, Ali Shawki, Jiang Li, Jonathan D. Mitchell, Jacqueline Yu, Varadh Piamthai, Sarah H. Radi, Sana Hasnain, Kamil Borkowski, John W. Newman, Declan F. McCole, Meera G. Nair, Ansel Hsiao, James Borneman, Frances M. Sladek
Publikováno v:
Gut Microbes, Vol 15, Iss 1 (2023)
ABSTRACTInflammatory bowel disease (IBD) is a multifactorial disease with increasing incidence in the U.S. suggesting that environmental factors, including diet, are involved. It has been suggested that excessive consumption of linoleic acid (LA, C18
Externí odkaz:
https://doaj.org/article/5cd2f4244d6b4c3b8efb161aa4fbaa8c
Autor:
Mueez U-Din, Vanessa D. de Mello, Marjo Tuomainen, Juho Raiko, Tarja Niemi, Tobias Fromme, Anton Klåvus, Nadine Gautier, Kimmo Haimilahti, Marko Lehtonen, Karsten Kristiansen, John W. Newman, Kirsi H. Pietiläinen, Jussi Pihlajamäki, Ez-Zoubir Amri, Martin Klingenspor, Pirjo Nuutila, Eija Pirinen, Kati Hanhineva, Kirsi A. Virtanen
Publikováno v:
Cell Reports, Vol 42, Iss 9, Pp 113131- (2023)
Summary: Cold-induced brown adipose tissue (BAT) activation is considered to improve metabolic health. In murine BAT, cold increases the fundamental molecule for mitochondrial function, nicotinamide adenine dinucleotide (NAD+), but limited knowledge
Externí odkaz:
https://doaj.org/article/1c0fa9c527de49b8bd7b766598b67913
Autor:
Chwan-Li Shen, John W. Newman, Moamen M. Elmassry, Kamil Borkowski, Ming-Chien Chyu, Chanaka Kahathuduwa, Volker Neugebauer, Bruce A. Watkins
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundTai Chi (TC) controls pain through mind–body exercise and appears to alter inflammatory mediators. TC actions on lipid biomarkers associated with inflammation and brain neural networks in women with knee osteoarthritic pain were investiga
Externí odkaz:
https://doaj.org/article/3dcad255c5cb4799b19fb610e29b188c
Autor:
Yining E. Wang, Catherine P. Kirschke, Leslie R. Woodhouse, Ellen L. Bonnel, Charles B. Stephensen, Brian J. Bennett, John W. Newman, Nancy L. Keim, Liping Huang
Publikováno v:
BMC Nutrition, Vol 8, Iss 1, Pp 1-16 (2022)
Abstract Background The effect of genetic polymorphisms on fasting blood lipid levels have been widely studied but the effects of these within the context of a high-fat meal challenge remain less characterized. The current study aimed to investigate
Externí odkaz:
https://doaj.org/article/b8b7a4c4a8234204806db9d50854f054
Autor:
Tiffany R. Bellomo, MD, Noah L. Tsao, BS, Hillary Johnston-Cox, MD, Kamil Borkowski, PhD, Gabrielle Shakt, BS, Renae Judy, MS, Jonni Moore, PhD, Sarah J. Ractcliffe, PhD, Oliver Fiehn, PhD, Thomas F. Floyd, MD, Felix W. Wehrli, PhD, Emile Mohler, MD, John W. Newman, PhD, Scott M. Damrauer, MD
Publikováno v:
JVS - Vascular Science, Vol 3, Iss , Pp 379-388 (2022)
Objective: Supervised exercise therapy (SET) is the first line treatment for intermittent claudication owing to peripheral arterial disease. Despite multiple randomized controlled trials proving the efficacy of SET, there are large differences in ind
Externí odkaz:
https://doaj.org/article/a758e1d8e98643289225b31a295b4ee5
Autor:
Anita Wen, Ying Zhu, Sook Wah Yee, Brian I. Park, Kathleen M. Giacomini, Andrew S. Greenberg, John W. Newman
Publikováno v:
Metabolites, Vol 13, Iss 8, p 885 (2023)
The Thiamine Transporter 2 (THTR2) encoded by SLC19A3 plays an ill-defined role in the maintenance of tissue thiamine, thiamine monophosphate, and thiamine diphosphate (TDP) levels. To evaluate the impact of THTR2 on tissue thiamine status and metabo
Externí odkaz:
https://doaj.org/article/e8d403a0595546df826ac3ac157391ba