Zobrazeno 1 - 10
of 67
pro vyhledávání: '"JOHN T. ROSS"'
Autor:
Michael M. Meagher, Ian Henderson, S. Todd Swanson, Mehmet Inan, Michael P. Dux, Leonard A. Smith, Rick Barent, Theresa J. Smith, John T. Ross, Jayanta Sinha, Jicai Huang
Publikováno v:
Protein Expression and Purification. 75:177-185
A purification process for the manufacture of a recombinant C-terminus heavy chain fragment from botulinum neurotoxin serotype C [rBoNTC(H(c))], a potential vaccine candidate, has been defined and successfully scaled-up. The rBoNTC(H(c)) was produced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9246a718c520c09eba5fadac9d62c78
https://doi.org/10.1016/j.pep.2010.09.016
https://doi.org/10.1016/j.pep.2010.09.016
Autor:
Ian Henderson, Ardis Barthuli, Jayanta Sinha, Sarah A. Fanders, Mark A. Gouthro, John T. Ross, Michael M. Meagher, Theresa J. Smith, Mehmet Inan, Leonard A. Smith, Rick Barent, Bonnie M. Loveless, Todd Swanson, Shinichi Taoka
Publikováno v:
Journal of Biotechnology. 127:462-474
A process was developed for production of a candidate vaccine antigen, recombinant C-terminal heavy chain fragment of the botulinum neurotoxin serotype E, rBoNTE(H(c)) in Pichia pastoris. P. pastoris strain GS115 was transformed with the rBoNTE(H(c))
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a77eda10e29b60836ee90f99cc18fb64
https://doi.org/10.1016/j.jbiotec.2006.07.022
https://doi.org/10.1016/j.jbiotec.2006.07.022
Autor:
John T. Ross
Publikováno v:
The primary care companion for CNS disorders. 15(4)
Each day we use creative thinking to solve problems as they arise in our daily lives. Research and study have shown that there are 4 steps that allow us to be effective in critically solving problems throughout our lives. This is called the creative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::619dea4cf0fa70eb75bf184f6f04ea53
https://pubmed.ncbi.nlm.nih.gov/24392255
https://pubmed.ncbi.nlm.nih.gov/24392255
Autor:
Mehmet Inan, Theresa J. Smith, Michael P. Dux, Jayanta Sinha, Michael M. Meagher, Todd Swanson, Rick Barent, Leonard A. Smith, Robert Webb, Mark A. Gouthro, Bonnie M. Loveless, Ian Henderson, Ardis Barthuli, John T. Ross
Publikováno v:
Protein expression and purification. 45(2)
A recombinant C-terminus heavy chain fragment from botulinum neurotoxin serotype E (BoNT/E) is proposed as a vaccine against the serotype E neurotoxin. This fragment, rBoNTE(Hc), was produced intracellular in Pichia pastoris GS115 by a three-step fer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9a3520abb8c864b0480170f60d9b44f
https://pubmed.ncbi.nlm.nih.gov/16214371
https://pubmed.ncbi.nlm.nih.gov/16214371
Autor:
Daniel E. Schaufelberger, Mary P. Koleck, John A. Beutler, Angel M. Vatakis, A. Belinda Alvarado, Pamela Andrews, L. V. Marzo, G. M. Muschik, John Roach, John T. Ross, William B. Lebherz, Marie P. Reeves, Robert M. Eberwein, Lori L. Rodgers, Robert P. Testerman, Kenneth M. Snader, Salvatore Forenza
Publikováno v:
Journal of natural products. 54(5)
A novel process was designed for the large-scale isolation of bryostatin 1 from the bryozoan Bugula neritina L. in order to obtain multigram quantities of highly pure material for formulation studies, preclinical toxicology, and clinical trials in ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef5a911848774288fb7dd5491d0f8be
https://pubmed.ncbi.nlm.nih.gov/1800630
https://pubmed.ncbi.nlm.nih.gov/1800630
Publisher Summary This chapter discusses the expression of mammalian cytochrome P450 enzymes using yeast-based vectors. The analysis of structure–function relationships also requires that the catalytic activities of modified proteins be measured. F
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6c5d0e681f47cf43b2dbfda3bae4d921
https://doi.org/10.1016/0076-6879(91)06085-h
https://doi.org/10.1016/0076-6879(91)06085-h
Publikováno v:
Applied Biochemistry and Biotechnology. 22:1-11
A large-scale process was developed to purify L-asparaginase from submerged cultures of Erwinia carotovora. Cells from 880 L of fermentation broth were harvested and washed using a plate and frame type filter press. A cellular acetone powder was prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1e41fe47101f0fc4b8367e7d507dbf3
https://doi.org/10.1007/bf02922693
https://doi.org/10.1007/bf02922693
Publikováno v:
Applied biochemistry and biotechnology. 12(3)
A large-scale process was developed to purify gram quantities of a therapeutic enzyme, L-asparaginase, from submerged cultures of Erwinia carotovora. Cells were harvested from 150 L of fermentation broth and washed. A cellular acetone powder was prep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65cbae2ff5b06e215adc541a27b80ac4
https://pubmed.ncbi.nlm.nih.gov/3752984
https://pubmed.ncbi.nlm.nih.gov/3752984
Autor:
RAMESH C. PANDEY, CHABI C. KALITA, MARK E. GUSTAFSON, MARGARET C. KLINE, MICHAEL E. LEIDHECKER, JOHN T. ROSS
Publikováno v:
ACS Symposium Series ISBN: 9780841208902
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26e748fb3f6d32b6b19dfda65c4377ab
https://doi.org/10.1021/bk-1985-0271.ch009
https://doi.org/10.1021/bk-1985-0271.ch009
Publikováno v:
Anatomical Record: Advances in Integrative Anatomy & Evolutionary Biology; Apr2022, Vol. 305 Issue 4, p818-826, 9p