Multiploid CD61+ cells are the pre-dominant cell lineage infected during acute dengue virus infection in bone marrow.

Autor: Kristina B Clark, Sansanee Noisakran, Nattawat Onlamoon, Hui-Mien Hsiao, John Roback, Francois Villinger, Aftab A Ansari, Guey Chuen Perng

Publikováno v: PLoS ONE, Vol 7, Iss 12, p e52902 (2012)

Depression of the peripheral blood platelet count during acute infection is a hallmark of dengue. This thrombocytopenia has been attributed, in part, to an insufficient level of platelet production by megakaryocytes that reside in the bone marrow (BM

Externí odkaz: https://doaj.org/article/ad8d12116d9e431688aac034197fd10a

PATIENTS WITH ASTHMA OR ATOPIC DERMATITIS TAKING BIOLOGIC THERAPIES HAVE REDUCED SARS-COV-2 VACCINE RESPONSE AT SIX MONTHS

Autor: MARTIN C RUNNSTROM, NARAYANAIAH CHEEDARLA, PEDRO A LAMOTHE, SUNEETHAMMA CHEEDARLA, MAYURAN RAVINDRAN, RICHARD P RAMONELL, FABLIHA A ANAM, ROBERT SWERLICK, COLIN E SWENSON, CARMEN C POLITO, WENDY A NEVEU, RAHULKUMAR PATEL, CAROLINE Y KIM, IAN HENTENAAR, NATALIE S. HADDAD, JOHN DAISS, IGNACIO SANZ, SUNITA SHARMA, FERNANDO HOLGUIN, ANDREW NEISH, JOHN ROBACK, FRANCES E LEE

Publikováno v: Chest. 162:A2652-A2653

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8b187a3227e3907b3c605060ee4089e2
https://doi.org/10.1016/j.chest.2022.08.2166

Rapid, High Throughput, Automated Detection Of SARS-Cov-2 Neutralizing Antibodies Against Native-Like Vaccine And Delta Variant Spike Trimers

Autor: Narayanaiah Cheedarla, Hans Verkerke, Sindhu Potlapalli, Kaleb McLendon, Anamika Patel, Filipp Frank, Gregory Damhorst, Huixia Wu, William O'Sick, Daniel Graciaa, Fuad Hudaib, David Alter, Jeannette Bryksin, Eric Ortlund, Jeannette Guarner, Sara Auld, Sarita Shah, Wilbur Lam, Dawn Mattoon, Joseph Johnson, David Wilson, Madhav Dhodapkar, Sean Stowell, Andrew Neish, John Roback

Publikováno v: medRxiv

Traditional cellular and live-virus methods for detection of SARS-CoV-2 neutralizing antibodies (nAbs) are labor- and time-intensive, and thus not suited for routine use in the clinical lab to predict vaccine efficacy and natural immune protection. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f68df05fce87b3bb89e72bf4e7c43bf6
https://pubmed.ncbi.nlm.nih.gov/35194599

The Pandemic as a Catalyst for Digital Pathology Adoption as an LDT

Autor: Geoffrey Smith, Ross Raiff, Sunil Badve, Alyssa Krasinskas, John Roback

Publikováno v: American Journal of Clinical Pathology. 158:S19-S19

Whole-slide images (WSI) are the basis for the application of artificial intelligence/machine learning and other informatics methods to histological diagnosis and will further blur the line separating anatomic and clinical pathology. FDA classified W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f498ca5daec7c9bb5816650b394bf85e
https://doi.org/10.1093/ajcp/aqac126.033

Immune plasma for the treatment of severe influenza: an open-label, multicentre, phase 2 randomised study

Autor: John H Beigel, Pablo Tebas, Marie-Carmelle Elie-Turenne, Ednan Bajwa, Todd E Bell, Charles B Cairns, Shmuel Shoham, Jaime G Deville, Eric Feucht, Judith Feinberg, Thomas Luke, Kanakatte Raviprakash, Janine Danko, Dorothy O'Neil, Julia A Metcalf, Karen King, Timothy H Burgess, Evgenia Aga, H Clifford Lane, Michael D Hughes, Richard T Davey, Joseph Quinn, Yan Jiang, Robyn Hoelle, Nicole Iovine, Robert Shawn Wills, Socorro Pata, Monique Huggins, Belinda Manukian, Carrie Holland, Kelsey Brait, Taylor Hunt, Christopher Stowell, Amy Slater, Mary Townsends, Eugenia B Quackenbush, Yara A Park, Paul Gaither Jordan, Cherie Blanchet, Kevin Chronowski, Kathleen Alvarez, Darin Ostrander, Terry Woessner, Sandra Thoman, James Lin, Alyssa Ziman, Kavita Shankar, Tom Blok, Don Batts, Bob Beck, Gail Massey, Carol Bradley, Patricia Carey, Jenifer Baer, Eva Moore Whitehead, Sharon Kohrs, Robert Giulitto, Christina Schofield, Mary Fairchok, Susan Chambers, Cindy Baker, null RN, Michelle Parker, Marta Harshbarger, M Hong Nguyen, Mary Ellen Carey, Julie Paronish, Frank Cornell, Jim Cramer, Diana Lynn Pakstis, Michael G Ison, Richard Wunderink, Marshall Glesby, Kirsis Ham, Valery Hughes, Melissa Cushing, Cheryl Goss, Joanne Grenade, Pauline K Park, Lena M Napolitano, Krishnan Raghavendran, Robert C Hyzy, Robertson Davenport, Kristin Brierley, Theresa Downs, Michelle Ng Gong, Joan Uehlinger, Michael Lin, Janice Fritsche, Tondria Green, Bruce McLeod, Deena Patel, Mary F Bavaro, Robert Deiss, Carolyn Brandt, Stephanie Cammarata, Allan Kremp, Karine Hollis-Perry, Tahaniyat Lalani, Susan Banks, Jacqueline Johnson, Jason Maguire, Janet McNiff, Leslie E Rigg, Anuradha Ganesan, Irma Barahona, Steven Spencer, David Stagliano, Timothy Burgess, Daniel Talmor, Monique Mohammed, Valerie Banner-Goodspeed, Robert Salata, Robert Finberg, Jennifer Wang, Karen Longtine, Jaclyn Longtine, Mellissa O'Neil, Philippe R Bauer, Ognjen Gajic, Suanne M Weist, Jonathan Sevransky, Mona Brown, John Roback, John Oropello, Bridget Twohig, Jeffrey Jhang, Rahgu Seethala, Wilbur H Chen, Magali Fontaine, Kapil Saharia, Jennifer Husson, Roberta DeBiasi, Jurran L Wilson, Valli Ree Criss, Jocelyn Voell, Susan Leitman, James Wade Atkins, Hemaxi Patel, Traci Paige, Cathy Cantilena, Donald Siegel, Faye DeMuth, Craig H Fletcher, J Peter R Pelletier, Hassan Alnuaimat, Michelle Pourde

Publikováno v: The Lancet Respiratory Medicine

Summary Background Influenza causes substantial morbidity and mortality despite available treatments. Anecdotal reports suggest that plasma with high antibody titres to influenza might be of benefit in the treatment of severe influenza. Methods In th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcf098a2fe5bc689fd2080a3ec4ebf3d
https://doi.org/10.1016/s2213-2600(17)30174-1