Zobrazeno 1 - 10
of 134
pro vyhledávání: '"JOHN P. MCGRATH"'
Autor:
Cian J.H. Horneck Johnston, Anna E. Ledwith, Mimmi L.E. Lundahl, Hugo Charles-Messance, Emer E. Hackett, Simon D. O’Shaughnessy, Jonah Clegg, Hannah Prendeville, John P. McGrath, Aaron M. Walsh, Sarah Case, Hollie Austen Byrne, Parth Gautam, Elaine Dempsey, Sinead C. Corr, Frederick J. Sheedy
Publikováno v:
iScience, Vol 27, Iss 3, Pp 109030- (2024)
Summary: Fungal β-glucans are major drivers of trained immunity which increases long-term protection against secondary infections. Heterogeneity in β-glucan source, structure, and solubility alters interaction with the phagocytic receptor Dectin-1
Externí odkaz:
https://doaj.org/article/a82f686f0bfb42e89b2067f61614d09d
Autor:
Wei-Ting Tu, Ping-Chen Hou, Peng-Chieh Chen, Wan-Rung Chen, Hsin-Yu Huang, Jing-Yu Wang, Yi-Ting Huang, Yi-Huei Wu, Chun-Lin Su, Yen-An Tang, Hiroaki Iwata, Ken Natsuga, Sheau-Chiou Chao, H. Sunny Sun, Ming-Jer Tang, Julia Yu-Yun Lee, John A. McGrath, Chao-Kai Hsu
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 17, Iss 1, Pp 1-10 (2022)
Abstract Background Epidermolysis bullosa (EB) is a heterogeneous group of hereditary skin diseases characterized by skin fragility. Primary data on Taiwanese population remain scarce. Methods We gathered clinical information from EB patients at Nati
Externí odkaz:
https://doaj.org/article/0cb4dd617c1d453a9b25ad879496557a
Autor:
Adam Sheriff, Ina Guri, Paulina Zebrowska, Virginia Llopis-Hernandez, Imogen R. Brooks, Stavroula Tekkela, Kavita Subramaniam, Ruta Gebrezgabher, Gaetano Naso, Anastasia Petrova, Katarzyna Balon, Alexandros Onoufriadis, Dorota Kujawa, Martyna Kotulska, Gregory Newby, Łukasz Łaczmański, David R. Liu, John A. McGrath, Joanna Jacków
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Base editing introduces precise single-nucleotide edits in genomic DNA and has the potential to treat genetic diseases such as the blistering skin disease recessive dystrophic epidermolysis bullosa (RDEB), which is characterized by mutations
Externí odkaz:
https://doaj.org/article/03e319002a21459e8249bcc2341dc40e
Autor:
Sanne Grundvad Boelt, Oleguer Plana-Ripoll, Clara Albiñana, Bjarni Vilhjálmsson, John J. McGrath, Arieh S. Cohen
Publikováno v:
BMC Research Notes, Vol 15, Iss 1, Pp 1-7 (2022)
Abstract Objective We developed an assay to measure the concentration of 25 hydroxyvitamin D2 and D3 in protein extracts derived from stored neonatal dried blood spots. During this study, we postulated that these samples had been contaminated with ex
Externí odkaz:
https://doaj.org/article/fa2f5198545d476cb3c350d621f68e77
Autor:
Montserrat Ayala-Ramirez, Nathaniel MacNell, Lucy E. McNamee, John A. McGrath, Farida S. Akhtari, Matthew D. Curry, Askia K. Dunnon, Michael B. Fessler, Stavros Garantziotis, Christine G. Parks, David C. Fargo, Charles P. Schmitt, Alison A. Motsinger-Reif, Janet E. Hall, Frederick W. Miller, Shepherd H. Schurman
Publikováno v:
Environment International, Vol 171, Iss , Pp 107687- (2023)
Background: Concentrated animal feeding operations (CAFOs) are a source of environmental pollution and have been associated with a variety of health outcomes. Immune-mediated diseases (IMD) are characterized by dysregulation of the normal immune resp
Externí odkaz:
https://doaj.org/article/6fd750625d1e400ea420cb3e832fe69d
Gene expression analysis reveals a 5-gene signature for progression-free survival in prostate cancer
Autor:
Zhuofan Mou, Jack Spencer, Bridget Knight, Joseph John, Paul McCullagh, John S. McGrath, Lorna W. Harries
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Prostate cancer (PCa) is the second most common male cancer worldwide, but effective biomarkers for the presence or progression risk of disease are currently elusive. In a series of nine matched histologically confirmed PCa and benign samples, we car
Externí odkaz:
https://doaj.org/article/fb46fcd752c84a68a9ef78284fe42464
Autor:
Katie Lawther, Fernanda Godoy Santos, Linda Boniface Oyama, Francesco Rubino, Steven Morrison, Chris J. Creevey, John W. McGrath, Sharon Ann Huws
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Antimicrobial resistance (AMR) is a serious threat to public health globally; it is estimated that AMR bacteria caused 1.27 million deaths in 2019, and this is set to rise to 10 million deaths annually. Agricultural and soil environments act as antim
Externí odkaz:
https://doaj.org/article/cb2e30483ec84886a95b61d5417c4f98
Autor:
Flavia Galdi, Claudio Pedone, Christopher A. McGee, Margaret George, Annette B. Rice, Shah S. Hussain, Kadambari Vijaykumar, Evan R. Boitet, Guillermo J. Tearney, John A. McGrath, Audrey R. Brown, Steven M. Rowe, Raffaele A. Incalzi, Stavros Garantziotis
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) carry significant morbidity and mortality. AECOPD treatment remains limited. High molecular weight hyaluronan (HMW-HA) is a glycosaminoglycan sugar, which is a
Externí odkaz:
https://doaj.org/article/fdc3367685624b84b0f5e0595f48ae2f
Autor:
Oleguer Plana-Ripoll, Julie W. Dreier, Natalie C. Momen, Anders Prior, Nanna Weye, Preben Bo Mortensen, Carsten B. Pedersen, Kim Moesgaard Iburg, Maria Klitgaard Christensen, Thomas Munk Laursen, Esben Agerbo, Marianne G. Pedersen, Jørgen Brandt, Lise Marie Frohn, Camilla Geels, Jesper H. Christensen, John J. McGrath
Publikováno v:
PLoS Medicine, Vol 19, Iss 6 (2022)
Background The provision of different types of mortality metrics (e.g., mortality rate ratios [MRRs] and life expectancy) allows the research community to access a more informative set of health metrics. The aim of this study was to provide a panel o
Externí odkaz:
https://doaj.org/article/b8fdf521588448e5a8bd9736dc2d820d
Autor:
Giulio Castelpietra, Ann Kristin Skrindo Knudsen, Emilie E. Agardh, Benedetta Armocida, Massimiliano Beghi, Kim Moesgaard Iburg, Giancarlo Logroscino, Rui Ma, Fabrizio Starace, Nicholas Steel, Giovanni Addolorato, Catalina Liliana Andrei, Tudorel Andrei, Jose L Ayuso-Mateos, Maciej Banach, Till Winfried Bärnighausen, Francesco Barone-Adesi, Akshaya Srikanth Bhagavathula, Felix Carvalho, Márcia Carvalho, Joht Singh Chandan, Vijay Kumar Chattu, Rosa A.S. Couto, Natália Cruz-Martins, Paul I. Dargan, Keshab Deuba, Diana Dias da Silva, Adeniyi Francis Fagbamigbe, Eduarda Fernandes, Pietro Ferrara, Florian Fischer, Peter Andras Gaal, Alessandro Gialluisi, Juanita A. Haagsma, Josep Maria Haro, M. Tasdik Hasan, Syed Shahzad Hasan, Sorin Hostiuc, Licia Iacoviello, Ivo Iavicoli, Elham Jamshidi, Jost B. Jonas, Tamas Joo, Jacek Jerzy Jozwiak, Srinivasa Vittal Katikireddi, Joonas H. Kauppila, Moien A.B. Khan, Adnan Kisa, Sezer Kisa, Mika Kivimäki, Kamrun Nahar Koly, Ai Koyanagi, Manasi Kumar, Tea Lallukka, Berthold Langguth, Caterina Ledda, Paul H. Lee, Ilaria Lega, Christine Linehan, Joana A. Loureiro, Áurea M Madureira-Carvalho, Jose Martinez-Raga, Manu Raj Mathur, John J. McGrath, Enkeleint A. Mechili, Alexios-Fotios A. Mentis, Tomislav Mestrovic, Bartosz Miazgowski, Andreea Mirica, Antonio Mirijello, Babak Moazen, Shafiu Mohammed, Francesk Mulita, Gabriele Nagel, Ionut Negoi, Ruxandra Irina Negoi, Vincent Ebuka Nwatah, Alicia Padron-Monedero, Songhomitra Panda-Jonas, Shahina Pardhan, Maja Pasovic, Jay Patel, Ionela-Roxana Petcu, Marina Pinheiro, Richard Charles G. Pollok, Maarten J. Postma, David Laith Rawaf, Salman Rawaf, Esperanza Romero-Rodríguez, Luca Ronfani, Dominic Sagoe, Francesco Sanmarchi, Michael P Schaub, Nigussie Tadesse Sharew, Rahman Shiri, Farhad Shokraneh, Inga Dora Sigfusdottir, João Pedro Silva, Renata Silva, Bogdan Socea, Miklós Szócska, Rafael Tabarés-Seisdedos, Marco Torrado, Marcos Roberto Tovani-Palone, Tommi Juhani Vasankari, Massimiliano Veroux, Russell M. Viner, Andrea Werdecker, Andrea Sylvia Winkler, Simon I. Hay, Alize J. Ferrari, Mohsen Naghavi, Peter Allebeck, Lorenzo Monasta
Publikováno v:
The Lancet Regional Health. Europe, Vol 16, Iss , Pp 100341- (2022)
Summary: Background: Mental health is a public health issue for European young people, with great heterogeneity in resource allocation. Representative population-based studies are needed. The Global Burden of Disease (GBD) Study 2019 provides interna
Externí odkaz:
https://doaj.org/article/6f65bb3de4744dba95238ff8cb7aca42