Zobrazeno 1 - 10
of 20
pro vyhledávání: '"JOHN MOSCHERA"'
Publikováno v:
Pharmaceutical Research. 26:161-171
To develop empirical models for predicting the binding between a drug and beta-cyclodextrin. Specifically, the logarithm of the 1:1 binding constant is expressed as the function of various molecular descriptors of the drug. Many potential drugs exhib
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0078920a2c19d4d9dad78f114a654f8
https://doi.org/10.1007/s11095-008-9733-x
https://doi.org/10.1007/s11095-008-9733-x
Autor:
Robert W. Payne, Charles S. Henry, Jie Di, David Heilman, Brian L. Bray, John Moschera, Mark C. Manning, Ralph Tarantino, Sam Del Terzo, Rajiv Nayar
Publikováno v:
Biopolymers. 84:527-533
Self-interaction of macromolecules has been shown to play an important role in a number of physical processes, including crystallization, solubility, viscosity, and aggregation. Peptide self-interaction is not as well studied as for larger proteins,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8a1a6024051bd00c56eeeef1e880ab
https://doi.org/10.1002/bip.20554
https://doi.org/10.1002/bip.20554
Publikováno v:
Regulatory Peptides. :433-439
OB protein (or leptin) administration causes a long-lasting reduction in food intake and body weight in obese ob/ob mice. Neuropeptide Y, a stimulator of feeding, has been proposed to be a major mediator of the biological actions of OB protein. To te
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a843002473cec578c4719e871ab2817a
https://doi.org/10.1016/s0167-0115(98)00099-8
https://doi.org/10.1016/s0167-0115(98)00099-8
Publikováno v:
Journal of Chromatography A. 598:123-131
A method is described to enhance the resolution and detection sensitivity of proteins, peptides, and amino acids in capillary electrophoretic analysis of solution mixtures. The method consists of derivatizing the analytes with fluorescamine, which is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fabb906b8be04c20427d3b18fbc5109
https://doi.org/10.1016/0021-9673(92)85122-a
https://doi.org/10.1016/0021-9673(92)85122-a
Publikováno v:
Journal of Liquid Chromatography. 15:1163-1177
A quantitative spectrophotometrc assay for the determination of proline and hydroxyproline is described. The assay is based on the derivatization of the imino acids with the fluorogenic chromophore fluorescamine and the separation of the derivatized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::500fd91c7c095fdca75ce66ec64c75bc
https://doi.org/10.1080/10826079208018856
https://doi.org/10.1080/10826079208018856
Publikováno v:
Journal of Chromatography A. 559:307-315
Several methods are available for determining the components present in a typical pharmaceutical dosage form. Although some of these methods are simple and have received wide pharmaceutical industry acceptance over many years, several limitations sti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f84980a569a24b5d26ffdcc3f1a60bc3
https://doi.org/10.1016/0021-9673(91)80080-z
https://doi.org/10.1016/0021-9673(91)80080-z
Publikováno v:
International journal of pharmaceutics. 252(1-2)
Due to the fact that some proteins have a tendency to bind to glass surfaces, plastic CZ-resin vials were evaluated as an alternative material to glass vials for packaging protein-based parenteral formulations. Physico-chemical tests including protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c85946da6da454dbb52930256e72f55
https://pubmed.ncbi.nlm.nih.gov/12550796
https://pubmed.ncbi.nlm.nih.gov/12550796
Publikováno v:
Journal of chromatography. 608(1-2)
Capillary electrophoresis has proved to be a versatile method for the determination of proteins, peptides and amino acids in pharmaceutical formulations. For quantification of the capillary electrophoresis data, however, significant errors may result
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5def6068643b2f2f08d03d021ce92f76
https://pubmed.ncbi.nlm.nih.gov/1430022
https://pubmed.ncbi.nlm.nih.gov/1430022
Publikováno v:
Pharmaceutical Research; Jan2009, Vol. 26 Issue 1, p161-171, 11p
Autor:
Max D. Summers, Hans-Werner Lahm, Gale E. Smith, Grace Ju, Brad L. Ericson, Richard Anthony Chizzonite, John Moschera
Publikováno v:
Proceedings of the National Academy of Sciences. 82:8404-8408
A cDNA coding for human interleukin 2 (IL-2) was inserted into the genome of Autographa californica nuclear polyhedrosis virus adjacent to the polyhedrin promoter. Cells infected with recombinant virus produced high levels of Mr 15,500 IL-2 polypepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20903241ca35c39ee6ecea5f647f627e
https://doi.org/10.1073/pnas.82.24.8404
https://doi.org/10.1073/pnas.82.24.8404