Zobrazeno 1 - 10
of 44
pro vyhledávání: '"JOHN H. HEILIGENSTEIN"'
Autor:
S. Kaplan, Donald Harder, John H. Heiligenstein, Charles D. Casat, Stephen G. West, J. Busner, Ralf W. Dittmann, J. F. Wernicke
Publikováno v:
Journal of Attention Disorders. 8:45-52
Objective: To compare the safety and efficacy of atomoxetine, a selective inhibitor of the norepinephrine transporter, versus placebo in Attention-Deficit/Hyperactivity Disorder (ADHD) patients with comorbid Oppositional Defiant Disorder (ODD). Metho
Publikováno v:
Journal of Child and Adolescent Psychopharmacology. 14:412-417
The aim of this study was to assess the safety of subchronic fluoxetine treatment for major depressive disorder (MDD) in children and adolescents.Patients received up to 19 weeks of treatment with fluoxetine, 10 mg-60 mg daily. Safety was evaluated t
Autor:
Joachim F. Wernicke, David Michelson, John H. Heiligenstein, Haitao Gao, Donald A. Girod, Jeffrey W. Brown, Humberto Quintana, Douglas E. Faries, Douglas Kelsey, Robert Lipetz
Publikováno v:
Drug Safety. 26:729-740
Background: Atomoxetine is a highly specific presynaptic inhibitor of the noradrenaline (norepinephrine) transporter that was recently approved in the US for the treatment of patients with attention-deficit/hyperactivity disorder (ADHD). Adverse effe
Autor:
John H. Heiligenstein, Joseph Biederman, Christopher J. Kratochvil, William Z. Potter, Douglas E. Faries, Thomas J. Spencer, C. Keith Conners
Publikováno v:
The Journal of Clinical Psychiatry. 63:1140-1147
Background: Atomoxetine is a nonstimulant drug being studied for the treatment of attention-deficit/hyperactivity disorder (ADHD). Atomoxetine is a highly specific inhibitor of the presynaptic norepinephrine transporter with minimal affinity for othe
Autor:
John H. Heiligenstein, S Michelle Morin, Kenneth W. Perry, David L. Nelson, Frank P. Bymaster, Susan K. Hemrick-Luecke, Penny G. Threlkeld, Jason Katner, Donald R. Gehlert
Publikováno v:
Neuropsychopharmacology. 27:699-711
The selective norepinephrine (NE) transporter inhibitor atomoxetine (formerly called tomoxetine or LY139603) has been shown to alleviate symptoms in Attention Deficit/Hyperactivity Disorder (ADHD). We investigated the mechanism of action of atomoxeti
Autor:
Sharon L. Hoog, Karen Dineen Wagner, Daniel E. Ernest, Jennie G. Jacobson, John H. Heiligenstein, Mary E. Nilsson, Graham J. Emslie, Eileen Brown
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 41:1205-1215
This report presents results from the acute treatment phase of a clinical trial designed to confirm efficacy of a fixed dose of 20 mg of fluoxetine in children and adolescents with major depressive disorder (MDD).After a 3-week screening period, 122
Publikováno v:
Journal of Clinical Psychopharmacology. 21:561-568
The 1-week single-blind placebo lead-in has long been a standard in double-blind psychopharmacology clinical trials. Although a lead-in period is often necessary (e.g., to receive laboratory results before randomization), some authors have demonstrat
Publikováno v:
Journal of Attention Disorders. 5:107-115
There are several parent- and teacher-scored rating scales that are validated and available for assessing the severity of ADHD symptoms in pediatric populations. However, we are not aware of any symptom severity rating scales with published validatio
Autor:
DANIEL A. GELLER, SHARON L. HOOG, JOHN H. HEILIGENSTEIN, RANDALL K. RICARDI, ROY TAMURA, STACY KLUSZYNSKI, JENNIE G. JACOBSON, null FLUOXETINE PEDIATRIC OCD STUDY TEAM
Publikováno v:
Journal of the American Academy of Child & Adolescent Psychiatry. 40:773-779
Objective This study assesses the efficacy and tolerability of fluoxetine in the acute treatment of child and adolescent obsessive-compulsive disorder (OCD) during a 13-week, double-blind, placebo-controlled study. Method Eligible patients aged 7 to
Publikováno v:
Psycho-Oncology. 7:291-300
Background. This study was conducted to determine the efficacy and tolerability of fluoxetine and desipramine in treating depressive symptoms in women with cancer. Method. In this prospective, 6-week, double-blind, placebo-controlled trial, we compar