Výsledky vyhledávání - "JOHANNES P. F. G. HELSPER"

Expression of natural human β1,4-GalT1 variants and of non-mammalian homologues in plants leads to differences in galactosylation of N-glycans

Autor: Dirk Bosch, Maurice Henquet, Gerard J. A. Rouwendal, Johannes P. F. G. Helsper, Thamara Hesselink, Dion E.A. Florack

Publikováno v: Transgenic Research, 23(5), 717-728
Transgenic Research 23 (2014) 5

β1,4-Galactosylation of plant N-glycans is a prerequisite for commercial production of certain biopharmaceuticals in plants. Two different types of galactosylated N-glycans have initially been reported in plants as the result of expression of human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b49e8dba07b64ddd34e9e546529c9b
https://doi.org/10.1007/s11248-014-9806-z

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Physicochemical characterization of titanium dioxide pigments using various techniques for size determination and asymmetric flow field flow fractionation hyphenated with inductively coupled plasma mass spectrometry

Autor: Zahira E. Herrera Rivera, Peter C. Tromp, Johannes P. F. G. Helsper, Ruud J. B. Peters, Margaretha E. M. van Bemmel, Frank von der Kammer, Thilo Hofmann, Stefan Weigel, Stephan Wagner

Publikováno v: Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry 408 (2016) 24
Analytical and Bioanalytical Chemistry, 408(24), 6679-6691

Seven commercial titanium dioxide pigments and two other well-defined TiO2 materials (TiMs) were physicochemically characterised using asymmetric flow field flow fractionation (aF4) for separation, various techniques to determine size distribution an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2689ac50e81439449c7234dbbe150c6a
https://pubmed.ncbi.nlm.nih.gov/27469116

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Antioxidative and immunomodulating activities of polysaccharide extracts of the medicinal mushrooms Agaricus bisporus, Agaricus brasiliensis, Ganoderma lucidum and Phellinus linteus

Autor: Dragica Jakovljević, Anita Klaus, Johannes P. F. G. Helsper, Miomir Nikšić, L.J.L.D. van Griensven, Maja Kozarski

Publikováno v: Food Chemistry, 129(4), 1667-1675
Food Chemistry
Food Chemistry 129 (2011) 4

Partially purified polysaccharides were obtained from four medicinal mushroom species, Agaricus bisporus, Agaricus brasiliensis, Phellinus linteus and Ganoderma lucidum by hot water extraction, followed by ethanol precipitation. The four samples cont

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22dee4661b3fab9505aae668a0a736fc
https://doi.org/10.1016/j.foodchem.2011.06.029

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Thermodynamic characterization of the PR-10 allergens Bet v 1, Api g 1 and Dau c 1 and pH-dependence of nApi g 1 and nDau c 1

Autor: Huub F. J. Savelkoul, M.A.J.S. van Boekel, M.A. Bollen, Johannes P. F. G. Helsper, Harry J. Wichers

Publikováno v: Food Chemistry 119 (2010) 1
Food Chemistry, 119(1), 241-248

Natural and recombinant Bet v 1, the major birch pollen allergen, and homologous allergens, Api g 1 and Dau c 1, from celery and carrot, respectively, were studied by CD spectroscopy under conditions of varying denaturant concentration, pH and temper

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::001d9007b4ce3d2b864be83f052c35e4
https://doi.org/10.1016/j.foodchem.2009.06.013

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Synthesis of Lewis X epitopes on plant N-glycans

Autor: Jan H.G. Cordewener, Dion E.A. Florack, Johannes P. F. G. Helsper, Thamara Hesselink, Dirk Bosch, Gerard J. A. Rouwendal

Publikováno v: Carbohydrate Research : an international journal 344 (2009) 12
Carbohydrate Research : an international journal, 344(12), 1487-1493

Glycoproteins from tobacco line xFxG1, in which expression of a hybrid beta-(1--4)-galactosyltransferase (GalT) and a hybrid alpha-(1--3)-fucosyltransferase IXa (FUT9a) is combined, contained an abundance of hybrid N-glycans with Lewis X (Le(X)) epit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373e46c8432cdac8a32273a255ce4334
https://doi.org/10.1016/j.carres.2009.05.003

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Phenolic Compounds Present in Medicinal Mushroom Extracts Generate Reactive Oxygen Species in Human Cells In Vitro

Autor: Song Wei, Johannes P. F. G. Helsper, L.J.L.D. van Griensven

Publikováno v: International Journal of Medicinal Mushrooms 10 (2008) 1
International Journal of Medicinal Mushrooms, 10(1), 1-13

Hot-water extracts of the higher Basidiomycetes Agaricus bisporus (J. Lge) Imbach, A. brasiliensis S. Wasser et al., Coprinus comatus (O.F. Mull.) Pers., Ganoderma lucidum (W. Curt.: Fr.) P. Karst., and Phellinus linteus (Berk. et Curt.) Teng were ma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75058762debe31ab1c31de586ebb7037
https://doi.org/10.1615/intjmedmushr.v10.i1.20

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Efficient introduction of a bisecting GlcNAc residue in tobacco N-glycans by expression of the gene encoding human N-acetylglucosaminyltransferase III

Autor: Carolien A. M. Koeleman, Hans Bakker, Irma van Die, Dion E.A. Florack, Dirk Bosch, Geert Stoopen, André M. Deelder, Gerard J. A. Rouwendal, Johannes P. F. G. Helsper, Manfred Wuhrer, Cornelis H. Hokke

Publikováno v: Glycobiology, 17(3), 334-344
Glycobiology 17 (2007) 3

In this study, we show that introduction of human N-acetylglucosaminyltransferase (GnT)-III gene into tobacco plants leads to highly efficient synthesis of bisected N-glycans. Enzymatically released N-glycans from leaf glycoproteins of wild-type and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b130acd77381041a8dcde47eefb27154
https://doi.org/10.1093/glycob/cwl078

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Purification and characterization of natural Bet v 1 from birch pollen and related allergens from carrot and celery

Autor: Mirko A. Bollen, Aranzazu Garcia, Johannes P. F. G. Helsper, Harry J. Wichers, Martinus A.J.S. van Boekel, Jan H.G. Cordewener, Huub F. J. Savelkoul

Publikováno v: Molecular Nutrition & Food Research 51 (2007) 12
Molecular Nutrition & Food Research, 51(12), 1527-1536

Birch pollen allergy is predominantly caused by the major allergen Bet v 1 and can lead to crossreactions with homologous proteins in food. Two major cross-reactive food allergens are Dau c 1 from carrot and Api g 1 from celery, which have never been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e2871311470e6d29a375676b7a1ed37
https://doi.org/10.1002/mnfr.200700119

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Translocation of differently sized and charged polystyrene nanoparticles in in vitro intestinal cell models of increasing complexity

Autor: Peter C. Tromp, Ivonne M.C.M. Rietjens, Evelien Kramer, Meike van der Zande, Agata P. Walczak, Peter J.M. Hendriksen, Hans Bouwmeester, Johannes P. F. G. Helsper

Publikováno v: Nanotoxicology 9 (2015) 4
Nanotoxicology, 9(4), 453-461
Nanotoxicology, 4, 9, 453-461

Intestinal translocation is a key factor for determining bioavailability of nanoparticles (NPs) after oral uptake. Therefore, we evaluated three in vitro intestinal cell models of increasing complexity which might affect the translocation of NPs: a m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6446c7039f8c60c5caec9728702f0672
https://pubmed.ncbi.nlm.nih.gov/25093449

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Characterisation and quantification of liposome-type nanoparticles in a beverage matrix using hydrodynamic chromatography and MALDI–TOF mass spectrometry

Autor: Ruud J. B. Peters, Johannes P. F. G. Helsper, Stefan Weigel, Lambertus Brouwer

Publikováno v: Analytical and Bioanalytical Chemistry 405 (2013) 4
Analytical and Bioanalytical Chemistry
Analytical and Bioanalytical Chemistry, 405(4), 1181-1189

This paper describes the characterisation of liposome-type nanoparticles (NPs) dispersed in a beverage matrix. Characterisation is based on a two-step procedure: first, liposomes are separated on the basis of size in the nanometre range by use of hyd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5efe917b773da3abb4ab948fabc0fe9
https://research.wur.nl/en/publications/characterisation-and-quantification-of-liposome-type-nanoparticle

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