Zobrazeno 1 - 10
of 46
pro vyhledávání: '"JOEL R. HAYNES"'
Autor:
Deborah Heydenburg Fuller, Premeela Rajakumar, Jenny W Che, Amithi Narendran, Julia Nyaundi, Heather Michael, Eric J Yager, Cristy Stagnar, Brendon Wahlberg, Rachel Taber, Joel R Haynes, Fiona C Cook, Peter Ertl, John Tite, Angela M Amedee, Michael Murphey-Corb
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33715 (2012)
Immunotherapies that induce durable immune control of chronic HIV infection may eliminate the need for life-long dependence on drugs. We investigated a DNA vaccine formulated with a novel genetic adjuvant that stimulates immune responses in the blood
Externí odkaz:
https://doaj.org/article/50fbf5aa9ff144e2b051ecbdca5f66e8
Autor:
Gabriel I. Parra, Kim Y. Green, Ross Taylor, Charles Richardson, Joel R. Haynes, Stanislav V. Sosnovtsev, Karin Bok
Publikováno v:
Vaccine. 30:3580-3586
Noroviruses, a major cause of acute gastroenteritis worldwide, present antigenic diversity that must be considered for the development of an effective vaccine. In this study, we explored approaches to increase the broad reactivity of virus-like parti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e381107db87d20ce77be03f8c81fac3
https://doi.org/10.1016/j.vaccine.2012.03.050
https://doi.org/10.1016/j.vaccine.2012.03.050
Autor:
Joel R Haynes
Publikováno v:
Expert Review of Vaccines. 8:435-445
Enveloped virus-like particle (VLP) vaccines containing influenza hemagglutinin (HA) and neuraminidase (NA) antigens are produced easily in insect or mammalian cells via the simultaneous expression of HA and NA along with a viral core protein, such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7800b7327ec4b23965b0bee0a7175a3
https://doi.org/10.1586/erv.09.8
https://doi.org/10.1586/erv.09.8
Autor:
Tim Shipley, Premeela A. Rajakumar, Deborah H. Fuller, David I. Watkins, Christopher W. McMahon, Joel R. Haynes, Todd M. Allen, James T. Fuller, Afrouz Bazmi, Mary S. Wu, Michael Murphey-Corb, Anita M. Trichel, Bianca R. Mothé
Publikováno v:
Virology. 348(1):200-215
DNA immunization in conjunction with antiretroviral therapy was evaluated in SIV-infected rhesus macaques treated with [R]-9-[2-phosphonylmethoxypropyl]adenine (PMPA). Macaques were immunized monthly with DNA vaccines expressing either SIV gag/tat or
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bf0e784d08fa42bb082caf35236f922
Publikováno v:
Advanced Drug Delivery Reviews. 57:1315-1342
Particle-mediated epidermal delivery (PMED) of DNA vaccines is based on the acceleration of DNA-coated gold directly into the cytoplasm and nuclei of living cells of the epidermis, facilitating DNA delivery and gene expression. Professional antigen-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bc1efb7ab430c8460c48fa7ec4d449
https://doi.org/10.1016/j.addr.2005.01.012
https://doi.org/10.1016/j.addr.2005.01.012
Autor:
Robert A. Gramzinski, Heather L. Davis, Joel R. Haynes, Michael J. McCluskie, Joseph C. Santoro, James T. Fuller, Robert H. Purcell, Cynthia L. Brazolot Millan, Georg Widera, Harriet L. Robinson
Publikováno v:
Molecular Medicine. 5:287-300
In spite of the large number of studies that have evaluated DNA-based immunization, few have directly compared the immune responses generated by different routes of immunization, particularly in non-human primates. Here we examine the ability of a he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b511890a8147d0709a814b9360545c
https://doi.org/10.1007/bf03402065
https://doi.org/10.1007/bf03402065
Publikováno v:
Vaccine. 15:1349-1352
Gene gun-based DNA immunization using vectors encoding HIV-1 gp120 or influenza virus nucleoprotein result in Th2-like immune responses following successive immunizations. The codelivery of vectors encoding IL-2, IL-7, or IL-12 blocked this effect by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4899862a34f540e2e21807511a970d6
https://doi.org/10.1016/s0264-410x(97)00036-4
https://doi.org/10.1016/s0264-410x(97)00036-4
Autor:
Ronald C. Montelaro, Janice E. Clements, Joel R. Haynes, Dennis L Panicali, Michael Murphey-Corb, Laura Simpson, Kelly Stefano Cole, Deborah H. Fuller
Publikováno v:
Immunology and Cell Biology. 75:389-396
Gene gun-based DNA immunization alone or in combination with recombinant vaccinia vectors was evaluated for the ability to elicit protective immune responses in rhesus macaques challenged with a pathogenic, heterologous simian immunodeficiency virus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f41b6dd8189ef0252b9ba04d644c0404
https://doi.org/10.1038/icb.1997.61
https://doi.org/10.1038/icb.1997.61
Autor:
Deborah H. Fuller, Susan W. Barnett, Barbara Doe, Joel R. Haynes, Christopher M. Walker, Sabita Rajasekar, Kathelyn S. Steimer, Harold Legg
Publikováno v:
Vaccine. 15:869-873
Small animals were immunized with plasmid DNA encoding HIV-1 envelope gp120 either intramuscularly by needle injection (mice and guinea pigs) or epidermally with the Accell gene gun (guinea pits). Subsequently, the animals were boosted with a recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce9d86ebbbe828ba5d7ee7488ad941dd
https://doi.org/10.1016/s0264-410x(96)00264-2
https://doi.org/10.1016/s0264-410x(96)00264-2
Publikováno v:
Advanced Drug Delivery Reviews. 21:3-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1738cd3c84d4a83f834d0a6d2b952e5
https://doi.org/10.1016/0169-409x(96)00020-8
https://doi.org/10.1016/0169-409x(96)00020-8