Zobrazeno 1 - 10
of 131
pro vyhledávání: '"JOEL KEIZER"'
Publikováno v:
Biophysical Journal. 84(3):1580-1590
We have measured the initial propagation velocity of the sperm-induced Ca(2+) wave in the egg of Xenopus laevis and have compared it with the initial propagation velocities of the inositol triphosphate (IP(3))-induced and Ca(2+)-induced Ca(2+) waves.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78c294324d287cc4398192bccd14a6d8
Autor:
Joel Keizer, Christopher P. Fall
Publikováno v:
Journal of Theoretical Biology. 210:151-165
IP3-mediated Ca 2+ release plays a fundamental role in many cell signaling processes and has been the subject of numerous modeling studies. Only recently has the important role that mitochondria play in the dynamics of intracellular Ca 2+ signaling b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7f66ce77ef6a6fda9a2846e97495a98
https://doi.org/10.1006/jtbi.2000.2292
https://doi.org/10.1006/jtbi.2000.2292
Publikováno v:
Proceedings of the National Academy of Sciences. 96:6060-6063
When Ca 2+ is released from internal stores in living cells, the resulting wave of increased concentration can travel without deformation (continuous propagation) or with burst-like behavior (saltatory propagation). We analyze the “fire–diffuse
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::938ee79075e504640eb24f3c2486c025
https://doi.org/10.1073/pnas.96.11.6060
https://doi.org/10.1073/pnas.96.11.6060
Autor:
Joel Keizer
The structure of the theory ofthermodynamics has changed enormously since its inception in the middle of the nineteenth century. Shortly after Thomson and Clausius enunciated their versions of the Second Law, Clausius, Maxwell, and Boltzmann began ac
Autor:
Hak Yong Kim, Joel Keizer, Richard B. Marchase, Kyle W. Cunningham, Richard Nuccitelli, Peter Csutora, Andrej Bugrim, Zhengchang Su, J. Edwin Blalock, Michael R. Hanley
Publikováno v:
Proceedings of the National Academy of Sciences. 96:121-126
Depletion of endoplasmic reticulum Ca 2+ stores leads to the entry of extracellular Ca 2+ into the cytoplasm, a process termed capacitative or store-operated Ca 2+ entry. Partially purified extracts were prepared from the human Jurkat T lymphocyte ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::378775dc32636ad944b8d5fdc7cabfe5
https://doi.org/10.1073/pnas.96.1.121
https://doi.org/10.1073/pnas.96.1.121
Publikováno v:
Biophysical Journal. 75(2):595-600
Punctate releases of Ca2+, called Ca2+ sparks, originate at the regular array of t-tubules in cardiac myocytes and skeletal muscle. During Ca2+ overload sparks serve as sites for the initiation and propagation of Ca2+ waves in myocytes. Computer simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::890f6034dfc394befbbeaf2b0ef94a50
Autor:
Joel Keizer, Gerhard Magnus
Publikováno v:
American Journal of Physiology-Cell Physiology. 274:C1158-C1173
We continue our development of a kinetic model of bursting electrical activity in the pancreatic β-cell ( J. Keizer and G. Magnus. Biophys. J. 56: 229–242, 1989), including the influence of Ca2+handling by the mitochondria. Our minimal model of mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76185621d632657d1dbd077709e55bd5
https://doi.org/10.1152/ajpcell.1998.274.4.c1158
https://doi.org/10.1152/ajpcell.1998.274.4.c1158
Autor:
L. Levine, Joel Keizer
Publikováno v:
Biophysical Journal. 71(6):3477-3487
A simplified mechanism that mimics "adaptation" of the ryanodine receptor (RyR) has been developed and its significance for Ca2+(-)induced Ca2+ release and Ca2+ oscillations investigated. For parameters that reproduce experimental data for the RyR fr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c052ef882846bfd0a20ba89b1574aec1
Autor:
Joel Keizer, Andrzej Molski
Publikováno v:
The Journal of Chemical Physics. 104:3567-3578
Using ideas from statistical nonequilibrium thermodynamics we develop a spatially nonlocal theory of the influence of diffusion on rapid chemical reactions. The new approach generalizes the hydrodynamic (local) theory by including elementary events t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d795d1063c5b07d0c2764a49b621f8f6
https://doi.org/10.1063/1.471061
https://doi.org/10.1063/1.471061
Autor:
M.S. Jafri, Joel Keizer
Publikováno v:
Biophysical Journal. 69(5):2139-2153
We have investigated the effects of Ca2+ diffusion, mobile and stationary Ca2+ buffers in the cytosol, and Ca2+ handling by the endoplasmic reticulum on inositol 1,4,5-trisphosphate-induced Ca2+ wave propagation. Rapid equilibration of free and bound
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd94dd64b8ec8c7eb06f5c22c71744c0