Výsledky vyhledávání - "JOCELYN CHENG"

0351 Differential Effect of Lemborexant and Zolpidem on Wake Across the Night in Patients with Insomnia Disorder

Autor: Thomas Roth, Jocelyn Cheng, Dinesh Kumar, Margaret Moline

Publikováno v: SLEEP. 46:A155-A156

Introduction Insomnia can involve difficulty with falling and/or staying asleep; older adults tend to report more sleep maintenance issues. While zolpidem tartrate extended-release 6.25mg (ZOL) is indicated to treat sleep onset and maintenance, data

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fd140134c5b6e60687c44327e7975f38
https://doi.org/10.1093/sleep/zsad077.0351

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0353 Effect of Lemborexant on Sleep Architecture in Adult and Elderly Subjects with Mild to Severe Obstructive Sleep Apnea

Autor: Gary Zammit, Jocelyn Cheng, Nancy Hall, Dhara Shah, Margaret Moline

Publikováno v: SLEEP. 46:A156-A157

Introduction Lemborexant (LEM) is a dual-orexin-receptor antagonist approved to treat adults with insomnia. In such patients, LEM increased total sleep, with prominent increases in rapid eye movement (REM). Since patients with obstructive sleep apnea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dd4b2eb8bcbd68787477b16aad937697
https://doi.org/10.1093/sleep/zsad077.0353

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0364 The Effect of Lemborexant on Polysomnographic Sleep Parameters in Adults with Mild, Moderate, or Severe Obstructive Sleep Apnea

Autor: Margaret Moline, Jocelyn Cheng, Nancy Hall, Dhara Shah, Gary Zammit

Publikováno v: SLEEP. 46:A161-A162

Introduction Several commonly prescribed hypnotics may worsen respiratory function, especially in the elderly. Lemborexant (LEM) is a dual-orexin-receptor-antagonist approved to treat adults with insomnia. In Studies 102 (NCT03471871) and 113 (NCT046

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::afd1c437bddfe39c6277c12ad4bafe8f
https://doi.org/10.1093/sleep/zsad077.0364

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0407 Impact of Lemborexant on Daytime Ratings of Sleepiness/Alertness in Subjects with Insomnia Disorder and Baseline Sleepiness

Autor: Sonia Ancoli-Israel, Margaret Moline, Jocelyn Cheng, Dinesh Kumar

Publikováno v: SLEEP. 46:A180-A180

Introduction Since the use of sleep-promoting drugs can also lead to residual morning sleepiness, it is important to determine if a new hypnotic is associated with such a carryover effect of treatment. To this end, an assessment of sleepiness/alertne

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a100651887ed394444cfbad0cddfc436
https://doi.org/10.1093/sleep/zsad077.0407

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0354 Effect of Lemborexant on Sleep Architecture in Subjects with Comorbid Insomnia and Mild Obstructive Sleep Apnea from a Ph 3 Trial

Autor: Clete Kushida, Gary Zammit, Jocelyn Cheng, Dinesh Kumar, Margaret Moline

Publikováno v: SLEEP. 46:A157-A157

Introduction Many patients with insomnia have co-morbid obstructive sleep apnea (COMISA). Patients with obstructive sleep apnea (OSA) may also have decreased REM-sleep. Lemborexant (LEM) is a dual-orexin-receptor-antagonist approved to treat adults w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a9040137573fa369a1af73fb5b98a66
https://doi.org/10.1093/sleep/zsad077.0354

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0454 Response to Lemborexant in Older Subjects with Insomnia Disorder and Comorbid Pain at Baseline

Autor: Alan Kaplan, Jocelyn Cheng, Masahiro Suzuki, Dinesh Kumar, Manoj Malhotra, Margaret Moline, Elizabeth Pappadopulos

Publikováno v: Sleep. 45:A201-A201

Introduction The reciprocal relationship between pain and poor sleep has been well established. Pain interferes with sleep, and insomnia increases pain sensitivity, thus reducing quality of life. Therefore, it is of clinical importance to evaluate wh

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c546b53e9abed3c4231c7c82dd336a6f
https://doi.org/10.1093/sleep/zsac079.451

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