Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice

Autor: Alice P. Sowton, Andrew J. Murray, Simon James Tunster, Erica D. Watson, Ben D. McNally, Nisha Padmanabhan, Julian L. Griffin, Antonio Murgia, Aisha Yusuf

Publikováno v: Molecular Genetics and Metabolism Reports
Molecular Genetics and Metabolism Reports, Vol 23, Iss, Pp-(2020)

Nonalcoholic fatty liver disease (NAFLD) is associated with dietary folate deficiency and mutations in genes required for one‑carbon metabolism. However, the mechanism through which this occurs is unclear. To improve our understanding of this link,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5de79e1f7ef67cef5ce425b58d812c6
http://hdl.handle.net/10044/1/82233

Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice.

Autor: Sowton AP; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Padmanabhan N; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., Tunster SJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., McNally BD; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Murgia A; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK., Yusuf A; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK., Griffin JL; Department of Biochemistry, University of Cambridge, Cambridge, CB2 1GA, UK.; Section of Biomolecular Medicine, Department of Metabolism, Digestion and Reproduction, Imperial College London, London, SW7 2AZ, UK., Murray AJ; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK., Watson ED; Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, CB2 3EG, UK.; Centre for Trophoblast Research, University of Cambridge, Cambridge, CB2 3EG, UK.

Publikováno v: Molecular genetics and metabolism reports [Mol Genet Metab Rep] 2020 Mar 24; Vol. 23, pp. 100580. Date of Electronic Publication: 2020 Mar 24 (Print Publication: 2020).