Zobrazeno 1 - 10
of 119
pro vyhledávání: '"JO Hilgers"'
Publikováno v:
Scopus-Elsevier
Monoclonal antibodies, raised against purified human milk fat globule membranes, were applied to human tissue and the corresponding antigenic determinants detected by an immunoperoxidase method. In human breast tissue, the presence of antigenic deter
Autor:
Jo Hilgers, Jan P. A. Baak, Ellen C.M. Mommers, Silvia von Mensdorff-Pouilly, Dick J. Schol, Chris J.L.M. Meijer, Angelique M. Leonhart, Paul J. van Diest
Publikováno v:
International Journal of Cancer. 84:466-469
MUC1 mucin is a high molecular weight transmembrane glycoprotein expressed on the apical cell surface of normal glandular epithelia. In many human adenocarcinomas, this protein is up-regulated and/or underglycosylated, and its expression changes from
Autor:
Sadashige Sakuma, Nobuko Mori, Masaaki Okumoto, Kozaburo Esaki, Sang-Seop Han, Jo Hilgers, Jin-Suk Kim, Jyoji Yamate, Chang-Woo Song
Publikováno v:
Laboratory Animals. 31:248-253
A new cataract model originated in a recombinant inbred (RI) strain, CXS4 or CXSD (D), between BALB/cHeA(BALB/c or C) and STS/A(STS or S) mice. Opacity appeared as a white pinpoint focus in unpigmented eyes of albino mice from 5 weeks old. All the mi
Autor:
Jo Hilgers, Sybren L. Meijer, Jan B. Vermorken, G.G. Bon, Peter Kenemans, Rob A. Verstraeten, Silvia von Mensdorff-Pouilly, Gerard J. van Kamp
Publikováno v:
Clinical Chemistry. 43:585-593
The mucin glycoprotein-detecting assay CA 15-3 is a valuable tool for monitoring the course of disease in breast cancer patients. Assays of CA 15-3 are based on the use of two MAbs to polymorphic epithelial mucin (PEM). We evaluated the technical and
Publikováno v:
International journal of oncology. 2(3)
Immunohistochemical profiles of 23 cases of basal cell carcinoma (BCC) were examined and compared with adjacent normal skin using three keratin antibodies, 34betaB4, 312C8-1 and E3, which recognize keratin 1, 14 and 17, respectively. In normal skin,
Publikováno v:
Cancer Genetics and Cytogenetics. 69:100-107
To study a possible role(s) played by the trisomy and pentasomy of chromosome 13 in murine mammary tumors, we examined, in eight cloned established cell lines derived from a single BALB/c mammary tumor induced by MTV, a correlation between the presen
Autor:
D.J. Schol, J. Schalkwjjk, A.A. Verstraeten, Eleanor J. Mackie, Jo Hilgers, Ph. Hageman, G.J. Jongh
Publikováno v:
British Journal of Dermatology. 127:571-574
Summary Tenascin (hexabrachion, cytotactin) is an extracellular matrix glycoprotein whose expression is strongly increased in hyperproliferative skin diseases, as shown by immunohistochemistry with polyclonal sera. In this study we describe a new mon
Publikováno v:
Microbial Pathogenesis
To examine the genetic control of acute and late disease induced by a murine coronavirus, strain JHM (JHMV), BALB/cHeA, STS/A, F1 hybrids and 13 recombinant inbred (RI) strains between BALB/cHeA and STS/A mouse strains were inoculated intracerebrally
Autor:
Masanori Shinohara, Sotokichi Morii, Kazuto Yamada, Masuichiro Oka, Takeshi Harada, Airo Tsubura, Jian Wen Huang, Kazuo Isono, Masahiko Mori, Jo Hilgers
Publikováno v:
ACTA HISTOCHEMICA ET CYTOCHEMICA. 25:473-482
Immunohistochemical features of mucoepidermoid carcinoma (19 cases) in human salivary glands were studied by means of the detection of polymorphic epithelial mucin (PEM) assessed with the MAM-3 antigen using MoAbs 67D11 and 115G3, and the MAM-6 antig
Autor:
Nurul H. Sarkar, Shunsuke Imai, Seiich Umesako, Masanari Nakayama, Satomi Haga, Hiroshi Yamamoto, Manabu Maeda, Kouko Tatsumi, Jo Hilgers
Publikováno v:
Oncology Reports.
p53, a tumor suppressor gene, is a target of genetic alternations in many human and animal cancers. Compared to normal tissues, cancer tissues overexpress mutant p53 protein thus allowing their detection by a number of immunochemical procedures. To w