Zobrazeno 1 - 10
of 368
pro vyhledávání: '"JN Ihle"'
Publikováno v:
Blood. 84:1501-1507
Protein tyrosine phosphorylation has been hypothesized to play a key role in the growth signaling induced by erythropoietin (Epo), although the Epo receptor (EpoR), a member of the cytokine receptor superfamily, lacks a tyrosine kinase domain. Recent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ba92f01f6563799cb1964317dede565
https://doi.org/10.1182/blood.v84.5.1501.1501
https://doi.org/10.1182/blood.v84.5.1501.1501
Autor:
L James, ER Levy, E Parganas, K Morishita, S Gisselbrecht, JN Ihle, Veronica J. Buckle, D Oscier, S Fichelson
Publikováno v:
Blood. 83:1348-1354
Specific rearrangements involving 3q21 and 3q26 are well documented in acute myeloid leukemia (AML). Aberrant expression of the Ecotropic virus integration-1 (EVI1) gene, located at 3q26, has been reported in individuals with AML and translocations o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ef04311269c8fe9cc88b916f578c1ee
https://doi.org/10.1182/blood.v83.5.1348.1348
https://doi.org/10.1182/blood.v83.5.1348.1348
Publikováno v:
Blood. 81:1739-1744
To analyze the structure of the murine erythropoietin receptor (EpoR), wild-type or mutant EpoR cDNAs were expressed in cell lines, and the proteins that cross-linked with 125I-labeled erythropoietin (Epo) were analyzed by immunoprecipitation using a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ca1025d2aedac23f76b07ba3e46cfb9
https://doi.org/10.1182/blood.v81.7.1739.bloodjournal8171739
https://doi.org/10.1182/blood.v81.7.1739.bloodjournal8171739
Publikováno v:
Blood. 79:2849-2854
Fifteen children (age 1.2 to 9.4 years) with advanced neuroblastoma were treated with myelosuppressive chemotherapy (cyclophosphamide, cisplatin, doxorubicin) followed by 5 (n = 5), 10 (n = 5), or 15 (n = 5) micrograms/kg recombinant granulocyte colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49e7757371fc7e1f907c3b687b87a67c
https://doi.org/10.1182/blood.v79.11.2849.2849
https://doi.org/10.1182/blood.v79.11.2849.2849
Autor:
Kieslinger M, Woldman I, Moriggl R, Hofmann J, Jean-Christophe Marine, Jn, Ihle, Beug H, Decker T
Publikováno v:
Europe PubMed Central
Stat5 is activated by multiple receptors of hematopoietic cytokines. To study its role during hematopoiesis, we have generated primary chicken myeloblasts expressing different dominant-negative (dn) alleles of Stat5. This caused a striking inability
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9295f329bd51e36df855b146242519e9
https://pubmed.ncbi.nlm.nih.gov/10652277
https://pubmed.ncbi.nlm.nih.gov/10652277
Autor:
Jl, Cleveland, Troppmair J, Packham G, David Askew, Lloyd P, González-Garcia M, Nuñez G, Jn, Ihle, Ur, Rapp
Publikováno v:
Europe PubMed Central
Interleukin-3 (IL-3) is required for the proliferation, survival and differentiation of myeloid progenitors. In the absence of IL-3, murine myeloid 32D.3 cells accumulate in the G1 phase of the cell cycle and subsequently undergo programmed cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5d4deb7c6b637358bb9c5dfd6976c05f
https://pubmed.ncbi.nlm.nih.gov/8036007
https://pubmed.ncbi.nlm.nih.gov/8036007
Autor:
DR Rill, VM Santana, WM Roberts, T Nilson, LC Bowman, RA Krance, HE Heslop, RC Moen, JN Ihle, MK Brenner
Publikováno v:
Blood. 84(2)
Patients with solid tumors are increasingly being treated by autologous bone marrow transplantation (BMT). Although response rates appear to be increased, disease recurrence is the commonest cause of treatment failure. Whether relapse is entirely due
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974cd63d4950f61857d0e7b3cd29b069
https://pubmed.ncbi.nlm.nih.gov/8025266
https://pubmed.ncbi.nlm.nih.gov/8025266
Autor:
Hestdal K, Fw, Ruscetti, Jn, Ihle, Sten Eirik Waelgaard Jacobsen, Cm, Dubois, Wc, Kopp, Dl, Longo, Jr, Keller
Publikováno v:
Europe PubMed Central
Murine bone marrow cells expressing the cell surface Ag RB6-8C5 were identified by fluorescence-activated cell-sorting analysis using a rat IgG mAb. The fluorescent intensity of RB6-8C5 was variable on bone marrow cells. This made it possible to sepa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::2ee4244901e2935ae0b72e7fe4db16d8
https://pubmed.ncbi.nlm.nih.gov/1711076
https://pubmed.ncbi.nlm.nih.gov/1711076
Publikováno v:
Blood. 72:2007-2014
Serial observations of blast cell colony development from spleen cells of mice treated with 5-fluorouracil (5-FU) four days earlier revealed that either form of human interleukin-1 (IL-1 alpha or IL-1 beta) hastens the emergence of interleukin-3 (IL-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aa777a0846939278f62dbd1ff38f799f
https://doi.org/10.1182/blood.v72.6.2007.bloodjournal7262007
https://doi.org/10.1182/blood.v72.6.2007.bloodjournal7262007
Publikováno v:
Blood. 67:859-864
Using a serum-free culture system, we examined murine macrophage colony formation from bone marrow cells cultured in the presence of purified CSF-1, interleukin 3 (IL 3) or a combination of the two factors. CSF-1 supported macrophage and neutrophil-m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43cb39dccfab2654563feefa11dccceb
https://doi.org/10.1182/blood.v67.4.859.859
https://doi.org/10.1182/blood.v67.4.859.859