Zobrazeno 1 - 10
of 84
pro vyhledávání: '"JN Ihle"'
Publikováno v:
Blood. 84:1501-1507
Protein tyrosine phosphorylation has been hypothesized to play a key role in the growth signaling induced by erythropoietin (Epo), although the Epo receptor (EpoR), a member of the cytokine receptor superfamily, lacks a tyrosine kinase domain. Recent
Autor:
L James, ER Levy, E Parganas, K Morishita, S Gisselbrecht, JN Ihle, Veronica J. Buckle, D Oscier, S Fichelson
Publikováno v:
Blood. 83:1348-1354
Specific rearrangements involving 3q21 and 3q26 are well documented in acute myeloid leukemia (AML). Aberrant expression of the Ecotropic virus integration-1 (EVI1) gene, located at 3q26, has been reported in individuals with AML and translocations o
Publikováno v:
Blood. 81:1739-1744
To analyze the structure of the murine erythropoietin receptor (EpoR), wild-type or mutant EpoR cDNAs were expressed in cell lines, and the proteins that cross-linked with 125I-labeled erythropoietin (Epo) were analyzed by immunoprecipitation using a
Publikováno v:
Blood. 79:2849-2854
Fifteen children (age 1.2 to 9.4 years) with advanced neuroblastoma were treated with myelosuppressive chemotherapy (cyclophosphamide, cisplatin, doxorubicin) followed by 5 (n = 5), 10 (n = 5), or 15 (n = 5) micrograms/kg recombinant granulocyte colo
Autor:
Kieslinger M, Woldman I, Moriggl R, Hofmann J, Jean-Christophe Marine, Jn, Ihle, Beug H, Decker T
Publikováno v:
Europe PubMed Central
Stat5 is activated by multiple receptors of hematopoietic cytokines. To study its role during hematopoiesis, we have generated primary chicken myeloblasts expressing different dominant-negative (dn) alleles of Stat5. This caused a striking inability
Autor:
Jl, Cleveland, Troppmair J, Packham G, David Askew, Lloyd P, González-Garcia M, Nuñez G, Jn, Ihle, Ur, Rapp
Publikováno v:
Europe PubMed Central
Interleukin-3 (IL-3) is required for the proliferation, survival and differentiation of myeloid progenitors. In the absence of IL-3, murine myeloid 32D.3 cells accumulate in the G1 phase of the cell cycle and subsequently undergo programmed cell deat
Autor:
DR Rill, VM Santana, WM Roberts, T Nilson, LC Bowman, RA Krance, HE Heslop, RC Moen, JN Ihle, MK Brenner
Publikováno v:
Blood. 84(2)
Patients with solid tumors are increasingly being treated by autologous bone marrow transplantation (BMT). Although response rates appear to be increased, disease recurrence is the commonest cause of treatment failure. Whether relapse is entirely due
Autor:
Hestdal K, Fw, Ruscetti, Jn, Ihle, Sten Eirik Waelgaard Jacobsen, Cm, Dubois, Wc, Kopp, Dl, Longo, Jr, Keller
Publikováno v:
Europe PubMed Central
Murine bone marrow cells expressing the cell surface Ag RB6-8C5 were identified by fluorescence-activated cell-sorting analysis using a rat IgG mAb. The fluorescent intensity of RB6-8C5 was variable on bone marrow cells. This made it possible to sepa
Publikováno v:
Blood. 72:2007-2014
Serial observations of blast cell colony development from spleen cells of mice treated with 5-fluorouracil (5-FU) four days earlier revealed that either form of human interleukin-1 (IL-1 alpha or IL-1 beta) hastens the emergence of interleukin-3 (IL-
Publikováno v:
Blood. 67:859-864
Using a serum-free culture system, we examined murine macrophage colony formation from bone marrow cells cultured in the presence of purified CSF-1, interleukin 3 (IL 3) or a combination of the two factors. CSF-1 supported macrophage and neutrophil-m