Zobrazeno 1 - 10 of 333 pro vyhledávání: '"JN Crawley"'
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Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome
Autor: BB Gundersen, WT O’Brien, MD Schaffler, MN Schultz, T Tsukahara, S Martin Lorenzo, V Nalesso, AH Luo Clayton, T Abel, JN Crawley, SR Datta, Y Herault
A microdeletion on human chromosome 16p11.2 is one of the most common copy number variants associated with autism spectrum disorder and other neurodevelopmental disabilities. Arbaclofen, a GABA(B) receptor agonist that is FDA-approved for treating sp
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::51805576f66a8faa2114ede796687f20
https://doi.org/10.1101/2023.05.01.538987
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3
Hyperactivity and learning deficits in transgenic mice bearing a human mutant thyroid hormone beta1 receptor gene
Autor: Michael P. McDonald, Wong R, Goldstein G, Weintraub B, Sy, Cheng, Jn, Crawley
Publikováno v: Europe PubMed Central
Resistance to thyroid hormone (RTH) is a human syndrome mapped to the thyroid receptor beta (TRbeta) gene on chromosome 3, representing a mutation of the ligand-binding domain of the TRbeta gene. The syndrome is characterized by reduced tissue respon
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de29bd71a3da929691e5e1baf4e4a602
https://pubmed.ncbi.nlm.nih.gov/10454355
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5
Behavioral effects of ivermectin in mice
Autor: Ja, Davis, Paylor R, Michael P. McDonald, Libbey M, Ligler A, Bryant K, Jn, Crawley
Publikováno v: Europe PubMed Central
Ivermectin is a common anthelmintic drug, widely used in laboratory rodents for treatment of pinworm and mite infestations. We evaluated the action of ivermectin on sensitive behavioral tasks in mice during treatment for mites within a barrier facili
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::9cf2440992c2c63e4fce36944330a06b
http://europepmc.org/abstract/med/10403444
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6
Towards Preclinical Validation of Arbaclofen (R-baclofen) Treatment for 16p11.2 Deletion Syndrome.
Autor: Gundersen BB; Simons Foundation, New York, NY., O'Brien WT; University of Pennsylvania, Philadelphia, PA., Schaffler MD; MIND Institute, University of California Davis School of Medicine, Sacramento, CA., Schultz MN; MIND Institute, University of California Davis School of Medicine, Sacramento, CA., Tsukahara T; Harvard Medical School, Boston, MA., Lorenzo SM; Université de Strasbourg, CNRS UMR7104, INSERM U1258, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), Illkirch cedex, France., Nalesso V; Université de Strasbourg, CNRS UMR7104, INSERM U1258, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), Illkirch cedex, France., Luo Clayton AH; NIH BRAIN Initiative, Bethesda, MD., Abel T; University of Iowa, Iowa City, IA., Crawley JN; MIND Institute, University of California Davis School of Medicine, Sacramento, CA., Datta SR; Harvard Medical School, Boston, MA., Herault Y; Université de Strasbourg, CNRS UMR7104, INSERM U1258, Institut de Genetique et de Biologie Moleculaire et Cellulaire (IGBMC), Illkirch cedex, France.
Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Sep 14. Date of Electronic Publication: 2023 Sep 14.
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7
Akademický článek
Twenty years of discoveries emerging from mouse models of autism.
Autor: Crawley JN; University of California Davis MIND Institute, Sacramento, CA 95817, USA. Electronic address: crawley@ucdavis.edu.
Publikováno v: Neuroscience and biobehavioral reviews [Neurosci Biobehav Rev] 2023 Mar; Vol. 146, pp. 105053. Date of Electronic Publication: 2023 Jan 20.
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8
Akademický článek
Sexually dimorphic neuroanatomical differences relate to ASD-relevant behavioral outcomes in a maternal autoantibody mouse model.
Autor: Bruce MR; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA., Jones KL; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA.; MIND Institute, University of California, Davis, CA, USA., Vernon AC; Department of Basic and Clinical Neuroscience, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.; MRC Centre for Neurodevelopmental Disorders, King's College London, London, UK., Silverman JL; MIND Institute, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Crawley JN; MIND Institute, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Ellegood J; Mouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, ON, Canada., Lerch JP; Mouse Imaging Centre (MICe), Hospital for Sick Children, Toronto, ON, Canada.; Department of Medical Biophysics, The University of Toronto, Toronto, ON, Canada.; Wellcome Centre for Integrative Neuroimaging, The University of Oxford, Oxford, UK., Van de Water J; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA. javandewater@ucdavis.edu.; MIND Institute, University of California, Davis, CA, USA. javandewater@ucdavis.edu.
Publikováno v: Molecular psychiatry [Mol Psychiatry] 2021 Dec; Vol. 26 (12), pp. 7530-7537. Date of Electronic Publication: 2021 Jul 21.
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9
Akademický článek
Autism-specific maternal autoantibodies produce behavioral abnormalities in an endogenous antigen-driven mouse model of autism.
Autor: Jones KL; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA.; MIND Institute, University of California, Davis, CA, USA., Pride MC; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Edmiston E; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA., Yang M; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA.; Institute for Genomic Medicine, Columbia University Medical Center, New York, NY, USA., Silverman JL; MIND Institute, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Crawley JN; MIND Institute, University of California, Davis, CA, USA.; Department of Psychiatry and Behavioral Sciences, University of California, Davis, CA, USA., Van de Water J; Department of Internal Medicine, Division of Rheumatology, Allergy, and Clinical Immunology, University of California, Davis, CA, USA. javandewater@ucdavis.edu.; MIND Institute, University of California, Davis, CA, USA. javandewater@ucdavis.edu.
Publikováno v: Molecular psychiatry [Mol Psychiatry] 2020 Nov; Vol. 25 (11), pp. 2994-3009. Date of Electronic Publication: 2018 Jun 28.
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10
Akademický článek
Behavioral Evaluation of Angelman Syndrome Mice at Older Ages.
Autor: Dutta R; MIND Institute, Department of Psychiatry and Behavioral Sciences, University of California Davis School of Medicine, Sacramento, CA 95817, USA., Crawley JN; MIND Institute, Department of Psychiatry and Behavioral Sciences, University of California Davis School of Medicine, Sacramento, CA 95817, USA. Electronic address: crawley@ucdavis.edu.
Publikováno v: Neuroscience [Neuroscience] 2020 Oct 01; Vol. 445, pp. 163-171. Date of Electronic Publication: 2019 Nov 12.
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