Zobrazeno 1 - 8
of 8
pro vyhledávání: '"JM Kühnel"'
Publikováno v:
Leukemia. 11:1147-1155
Multidrug resistance (MDR) is characterized by a decrease in the efficiency of chemotherapeutic agents correlated with the expression and activity of a membrane protein: the permeability-glycoprotein (Pgp 170). Clinically, detection of MDR can be per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71506f4af64a8ee9008ab76dc1a344f1
https://doi.org/10.1038/sj.leu.2400698
https://doi.org/10.1038/sj.leu.2400698
Publikováno v:
Journal de Chimie Physique. 91:127-149
Les membranes biologiques separent des compartiments aqueux qui presentent des compositions ioniques differentes ce qui entraine l’existence de gradients electrochimiques transmembranaires. Le gradient de pH favorise l’accumulation des acides fai
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cd3dbd029fd3c3ade0758f102d701ca
https://doi.org/10.1051/jcp/1994910127
https://doi.org/10.1051/jcp/1994910127
Publikováno v:
Spectroscopy of Biological Molecules ISBN: 9789401041669
Some tumor cells become resistant to structurally unrelated antitumor drugs. The multidrug resistance phenotype (MDR) is characterized by a lowering of drug cellular accumulation associated with the expression of a 170-kDa glycoprotein, Pgp (Permeabi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3dc83ec62dffbb956d5232d356797718
https://doi.org/10.1007/978-94-011-0371-8_243
https://doi.org/10.1007/978-94-011-0371-8_243
Autor:
Kühnel JM; Program of Molecular Pharmacology and Experimental Therapeutics, Memorial Sloan-Kettering Cancer Center, New York, NY 10021, USA., Chiao JH, Sirotnak FM
Publikováno v:
Journal of cellular physiology [J Cell Physiol] 2000 Sep; Vol. 184 (3), pp. 364-72.
Autor:
Ferté J; Laboratoire de Reconnaissance Moléculaire et Cellulaire, URA CNRS 1843, Centre d'Etudes Pharmaceutiques, 5, rue J.B. Clément, 92296 Châtenay-Malabry Cedex, France., Kühnel JM, Chapuis G, Rolland Y, Lewin G, Schwaller MA
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 1999 Feb 11; Vol. 42 (3), pp. 478-89.
Autor:
Kühnel JM; BIOCIS, CNRS URA 1843, Faculté de Pharmacie, Châtenay Malabry, France., Perrot JY, Faussat AM, Marie JP, Schwaller MA
Publikováno v:
Leukemia [Leukemia] 1997 Jul; Vol. 11 (7), pp. 1147-55.
Autor:
Dodin G; Institut de Topologie et de Dynamique des Systèmes, Université Paris 7, CNRS URA 34, France., Kühnel JM, Demerseman P, Kotzyba J
Publikováno v:
Anti-cancer drug design [Anticancer Drug Des] 1993 Oct; Vol. 8 (5), pp. 361-8.
Autor:
Dodin G; Institut de Topologie et de Dynamique des Systèmes, Université Paris 7, CNRS URA 34, France., Kühnel JM, Demerseman P, Averbeck D, Nocentini S
Publikováno v:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 1992 Aug 14; Vol. 186 (3), pp. 1567-74.