Zobrazeno 1 - 10
of 938
pro vyhledávání: '"JM Goldman"'
Autor:
A Ferrant, W Arcese, JM Goldman, D Niederwieser, P Ljungman, B Hertenstein, L Verdonck, Hans-Jochem Kolb, A Schattenberg, N Jacobsen
Publikováno v:
Blood. 86:2041-2050
HE ROLE OF ALLOGENEIC lymphocytes in the eradication of leukemia is well established. In mice, transplantation of allogeneic bone marrow eliminated leukemia, and transplantation of marrow from syngeneic donors failed.’ Allogeneic marrow transplanta
Autor:
JM Goldman
Publikováno v:
Blood. 84:2833-2839
A primary function of the World Marrow Donor Association is to establish general guidelines covering collaboration between international donor registries and practice in regard to bone marrow transplants (BMTs) in which the donor and recipient reside
Publikováno v:
Blood. 81:2488-2491
We have previously shown that the chimeric gene ABL-BCR, formed on the derivative chromosome 9q+ as a result of the t(9;22) translocation, is transcriptionally active in 65% of chronic myeloid leukemia patients. We have now used the same technique, r
Autor:
JM Goldman, A S Taj, C. Wildmann, Philippe Lewalle, Jean-Louis Michaux, Marianne Philippe, Jean-Luc Vaerman, Y Larondelle, Philippe Martiat
Publikováno v:
Blood. 81:502-509
There is now strong evidence that the BCR-ABL gene product of the Philadelphia chromosome (P210) plays a crucial role in the pathogenesis of chronic myeloid leukemia (CML). We have previously shown that introduction of antisense oligonucleotides into
Autor:
Mw, Deininger, Sa, Vieira, Parada Y, Banerji L, Eric Lam, Peters G, Fx, Mahon, Köhler T, Jm, Goldman, Jv, Melo
Publikováno v:
Europe PubMed Central
Leukemia cells bearing the Philadelphia (Ph) chromosome express a Bcr-Abl fusion protein with deregulated protein tyrosine kinase (PTK) activity, which plays a central role in the malignant transformation. Many different signal transduction pathways
Publikováno v:
Blood. 79:1379-1381
Autor:
Kulkarni S, Heath C, Parker S, Andrew Chase, Iqbal S, Cf, Pocock, Kaeda J, Cwynarski K, Jm, Goldman, Nc, Cross
Publikováno v:
ResearcherID
Europe PubMed Central
Europe PubMed Central
We have studied a patient who presented with clinical features suggestive of chronic myeloid leukemia in accelerated phase. BCR-ABL transcripts were undetectable by reverse transcription-PCR, but a novel reciprocal translocation, t(5;10)(q33;q21.2),
Autor:
Olavarria E, Parker S, Craddock C, Philpott N, Tiniakou M, Andrew Chase, Kanfer E, Jf, Apperley, Jm, Goldman
Publikováno v:
Europe PubMed Central
The observation that patients with chronic myeloid leukemia (CML) may relapse following stem cell transplantation because of Philadelphia positive cells contaminating the graft have led to a variety of strategies to reduce this contamination. This st
Autor:
Rt, Silver, Sh, Woolf, Hehlmann R, Fr, Appelbaum, Anderson J, Bennett C, Jm, Goldman, François Guilhot, Hm, Kantarjian, Ae, Lichtin, Talpaz M, Tura S
Publikováno v:
Europe PubMed Central
Because there are differing opinions regarding treatment of patients in the chronic phase of chronic myeloid leukemia (CML), the American Society of Hematology convened an expert panel to review and document evidence-based benefits and harms of treat
Autor:
Rp, Gale, Hehlmann R, Mj, Zhang, Hasford J, Jm, Goldman, Heimpel H, Hochhaus A, Jp, Klein, Hj, Kolb, Pb, Mcglave, Jakob R Passweg, Pa, Rowlings, Ka, Sobocinski, Mm, Horowitz
Publikováno v:
Europe PubMed Central
Hydroxyurea, interferon, and HLA-identical sibling bone marrow transplantation are common therapies for chronic myelogenous leukemia (CML) in chronic phase. Which is best is controversial. The purpose of this study was to compare survival of patients