Zobrazeno 1 - 10
of 30
pro vyhledávání: '"JIYU JU"'
Publikováno v:
Journal of Immunology Research, Vol 2023 (2023)
Genetic factors play an important role in the pathogenesis of systemic lupus erythematosus (SLE), and abnormal Toll-like receptor (TLR) signaling pathways are closely related to the onset of SLE. In previous studies, we found that the mutant somatic
Externí odkaz:
https://doaj.org/article/81ec031d4722489da9b571c286344ee8
Publikováno v:
Mediators of Inflammation, Vol 2021 (2021)
A variant of somatic nuclear autoantigenic sperm protein (sNASP) was identified from the murine lupus susceptibility locus Sle2c1 by whole exome sequencing (WES). Previous studies have shown that mutant sNASP could synergize with the Faslpr mutation
Externí odkaz:
https://doaj.org/article/8c0538a7dd824bcfa2a7450dac039143
Autor:
Meiyu Peng, Qi Zhang, Yanqing Liu, Xiangdong Guo, Jiyu Ju, Lingzhi Xu, Yuanyuan Gao, Daquan Chen, Dongzhen Mu, Rongxin Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
L-4F is an apolipoprotein A-I (ApoA-I) mimetic peptide, it was engineered to imitate the anti-inflammatory and anti-oxidative activity of ApoA-I. In this paper, H7 cell was used to construct a mouse model of pancreatic cancer in situ, and the mice we
Externí odkaz:
https://doaj.org/article/1e0c53ab12c4445ca062950b37167f83
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
The Sle2c1rec1c (rec1c) sublocus is derived from the mouse lupus susceptibility 2 (Sle2) locus identified in the NZM2410 model. Our current study dissected the functional characters and the genetic basis of the rec1c locus relative to lupus when co-e
Externí odkaz:
https://doaj.org/article/55000ec82c0a4d8bb80c15b4e2352848
Autor:
Weiwei Yang, Anning Wang, Chunling Zhao, Qinghua Li, Zhifang Pan, Xuefu Han, Cuijuan Zhang, Guohui Wang, Chao Ji, Guili Wang, Guangtao Jia, Jiyu Ju, Wei Gao, Wenjing Yu, Xiaoying Liu, Xi Chen, Weiguo Feng, Zhiqin Gao, Jie Li, Chune Ren
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0166940 (2016)
Preeclampsia (PE) is one of the leading causes of maternal and perinatal mortality and morbidity. One of the main hallmarks observed in PE is impaired inflammation state. In the current study, we found that miR-125b was deregulated in placental tissu
Externí odkaz:
https://doaj.org/article/ea3422c77568499b9bc8f106811115cc
Publikováno v:
Molecular Biology Reports. 49:2475-2485
Anti-citrullinated protein antibodies are a hallmark of rheumatoid arthritis. It is widely acknowledged that the presence of ACPAs is the result of the interaction of genes, the environment and epigenetic modifications. The mechanism by which the fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e9154c9d71b33feedeffc857f85fef
https://doi.org/10.1007/s11033-021-07034-0
https://doi.org/10.1007/s11033-021-07034-0
Autor:
Hui Wang, Chaoran Li, Guifang Ren, Chunjuan Yang, Jiamei Sun, Lu Zhao, Wenchang Sun, Jiyu Ju, Donghua Xu
Publikováno v:
Autoimmunity reviews. 22(1)
Systemic lupus erythematosus (SLE) is an autoimmune disease with multiple organs involvement, abundant autoantibodies, complement activation, and immune complexes depositions. By regulating inflammation and immune homeostasis, cytokines have been wel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db439ec5d13678c8fe5c765e79eb0781
https://pubmed.ncbi.nlm.nih.gov/36252932
https://pubmed.ncbi.nlm.nih.gov/36252932
Publikováno v:
Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 38(7)
Objective To investigate how mutation of nuclear autoantigenic sperm protein (NASP) gene affects mouse liver fibrosis induced by concanavalinA (ConA) and its mechanism. Methods The wild-type B6 (B6-WT) mice were used as a control group, and the NASP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e7dc1fa14d1595c9310695aec9999d4f
https://pubmed.ncbi.nlm.nih.gov/35786450
https://pubmed.ncbi.nlm.nih.gov/35786450
Publikováno v:
Lupus. 31(3)
Background The genetic factor is a great driver of systemic lupus erythematosus. A Skint6 W168X allele was previously identified in the murine lupus susceptibility rec1d1 sublocus. The purpose of this study is to investigate the pathogenic role and m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::364579723012cee3a412fac26c7fb82e
https://pubmed.ncbi.nlm.nih.gov/35045734
https://pubmed.ncbi.nlm.nih.gov/35045734
Publikováno v:
Biochimica et biophysica acta. Reviews on cancer. 1877(3)
Kruppel-associated box (KRAB) zinc-finger proteins (KRAB-ZFPs) are the largest transcriptional/transcription-regulatory factor family in mammalian cells. The amino-terminal KRAB domain, which recruits other transcription-regulating proteins, and the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac47dd0e6af501665dea78cd577862ed
https://pubmed.ncbi.nlm.nih.gov/35483489
https://pubmed.ncbi.nlm.nih.gov/35483489