Zobrazeno 1 - 10
of 251
pro vyhledávání: '"JINSEU PARK"'
Autor:
Jin Kyun Park, Yu Jin Jang, Bo Ram Oh, Jieun Shin, Daekwon Bae, Nina Ha, Young il Choi, Gi Soo Youn, Jinseu Park, Eun Young Lee, Eun Bong Lee, Yeong Wook Song
Publikováno v:
Arthritis Research & Therapy, Vol 22, Iss 1, Pp 1-9 (2020)
Abstract Objectives Histone deacetylase (HDAC) 6 promotes inflammation. We investigated the anti-arthritic effects of CKD-506, a novel HDAC6 inhibitor, in vitro and in a murine model of arthritis as a novel treatment option for rheumatoid arthritis (
Externí odkaz:
https://doaj.org/article/ec12f8ed6ac94d528286a8f11c4b8039
Autor:
Yeon Joo Choi, Hyeon Ji Yeo, Min Jea Shin, Gi Soo Youn, Jung Hwan Park, Eun Ji Yeo, Hyun Jung Kwon, Lee Re Lee, Na Yeon Kim, Su Yeon Kwon, Su Min Kim, Dae Won Kim, Hyo Young Jung, Oh-Shin Kwon, Chan Hee Lee, Jong Kook Park, Keun Wook Lee, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 836 (2023)
Glutathione S-transferase pi (GSTpi) is a member of the GST family and plays many critical roles in cellular processes, including anti-oxidative and signal transduction. However, the role of anti-oxidant enzyme GSTpi against dopaminergic neuronal cel
Externí odkaz:
https://doaj.org/article/cfeb9ae807604b90a48f4d87ffe4aacf
Publikováno v:
Redox Biology, Vol 12, Iss , Pp 978-986 (2017)
Histone deacetylase 6 (HDAC6) likely is important in inflammatory diseases. However, how HDAC6 exerts its effect on inflammatory processes remains unclear. HIV-1 transactivator of transcription (Tat) activates NADPH oxidase resulting in generation of
Externí odkaz:
https://doaj.org/article/28891b5d69fd460d88e1eba163424942
Autor:
Yeon Joo Choi, Dae Won Kim, Min Jea Shin, Hyeon Ji Yeo, Eun Ji Yeo, Lee Re Lee, Yejin Song, Duk-Soo Kim, Kyu Hyung Han, Jinseu Park, Keun Wook Lee, Jong Kook Park, Won Sik Eum, Soo Young Choi
Publikováno v:
Molecules, Vol 26, Iss 11, p 3329 (2021)
Parkinson’s disease (PD) is characterized mainly by the loss of dopaminergic neurons in the substantia nigra (SN) mediated via oxidative stress. Although glutaredoxin-1 (GLRX1) is known as one of the antioxidants involved in cell survival, the effe
Externí odkaz:
https://doaj.org/article/3f618c898e6f49f5acfebd9aa23cb8de
Autor:
Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Seon Ae Eom, Duk-Soo Kim, Eun Young Park, Jong Hoon Park, Sung-Woo Cho, Jinseu Park, Won Sik Eum, Ora Son, Hyun Sook Hwang, Soo Young Choi
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 561-566 (2013)
We examined the ways in which fenobam could promote not onlythe transduction of PEP-1-FK506BP into cells and tissues but alsothe neuroprotective effect of PEP-1-FK506BP against ischemicdamage. Fenobam strongly enhanced the protective effect ofPEP-1-F
Externí odkaz:
https://doaj.org/article/de978395df6948f3a475068a1cf19afa
Publikováno v:
BMB Reports, Vol 46, Iss 8, Pp 410-415 (2013)
Adhesion molecules such as ICAM-1 are important in theinfiltration of leukocytes into the site of inflammation. In thisstudy, we investigated the inhibitory effects of curcumin onICAM-1 expression and monocyte adhesiveness as well as itsunderlying ac
Externí odkaz:
https://doaj.org/article/29e91c46b4b344b6a7593ccb7a2aec2f
Transduced PEP-1-FK506BP ameliorates corneal injury in Botulinum toxin A-induced dry eye mouse model
Autor:
Dae Won Kim, Sung Ho Lee, Sae Kwang Ku, Soo Hyun Cho, Sung-Woo Cho, Ga Hyeon Yoon, Hyun Sook Hwang, Jinseu Park, Won Sik Eum, Oh-Shin Kwon, Soo Young Choi
Publikováno v:
BMB Reports, Vol 46, Iss 2, Pp 124-129 (2013)
FK506 binding protein 12 (FK506BP) belongs to a family ofimmunophilins, and is involved in multiple biologicalprocesses. However, the function of FK506BP in cornealdisease remains unclear. In this study, we examined theprotective effects on dry eye d
Externí odkaz:
https://doaj.org/article/d6a7de7e84a94045a515e823c0955a23
Autor:
Yongsoo Park, Hyunok Kim, Leejin Park, Dongsoo Min, Jinseu Park, Sooyoung Choi, Moon Hyang Park
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130815 (2015)
Diabetic nephropathy (DN) is thought to be partially due to the injury of renal cells and the renal micro-environment by free radicals. Free radial scavenging agents that inhibit free radical damage may well prevent the development of underlying cond
Externí odkaz:
https://doaj.org/article/c95b166a546d4106a445da6fc1b197f8
Autor:
Mi Jin Kim, Hoon Jae Jeong, Dae Won Kim, Eun Jeong Sohn, Hyo Sang Jo, Duk-Soo Kim, Hyun Ah Kim, Eun Young Park, Jong Hoon Park, Ora Son, Kyu Hyung Han, Jinseu Park, Won Sik Eum, Soo Young Choi
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86034 (2014)
Paraoxonase 1 (PON1) is an antioxidant enzyme which plays a central role in various diseases. However, the mechanism and function of PON1 protein in inflammation are poorly understood. Since PON1 protein alone cannot be delivered into cells, we gener
Externí odkaz:
https://doaj.org/article/4fcab1c9b34a488a8f2b8fcd5f1b162b
Autor:
Yeon Joo Choi, Hyun Jung Kwon, Min Jea Shin, Dae Won Kim, Gi Soo Youn, Jung Hwan Park, Hyeon Ji Yeo, Eun Ji Yeo, Hyeong Seop Kim, Lee Re Lee, Na Yeon Kim, Su Yeon Kwon, Duk‐Soo Kim, Gun Woo Kim, Jinseu Park, Kyu Hyung Han, Keun Wook Lee, Jong Kook Park, Chan Hee Lee, Won Sik Eum, Soo Young Choi
Publikováno v:
The FEBS Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::65de8a43740770d18afd9afbf1e13067
https://doi.org/10.1111/febs.16721
https://doi.org/10.1111/febs.16721