Zobrazeno 1 - 10
of 81
pro vyhledávání: '"JINGXUAN HUANG"'
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by motor neuron degeneration. Dysregulation of long non-coding RNAs (lncRNAs) has been implicated in ALS pathogenesis but their roles remain unclear. Prev
Externí odkaz:
https://doaj.org/article/557857d1dc8142abb048b98da21255ce
Autor:
Yiyuan Cui, Chunyu Li, Bin Ke, Yi Xiao, Shichan Wang, Qirui Jiang, Xiaoting Zheng, Junyu Lin, Jingxuan Huang, Huifang Shang
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundA number of studies have explored the link between neurodegenerative disorders (NDDs) and albumin, the main protein in human plasma. However, the results have been inconsistent, highlighting the necessity for a detailed systemic analysis.Me
Externí odkaz:
https://doaj.org/article/c703999495b7495cb18976ee32093ade
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract The prevalence of Alzheimer’s disease (AD) is increasing as the population ages, and patients with AD have a poor prognosis. However, knowledge on factors for predicting the survival of AD remains sparse. Here, we aimed to systematically e
Externí odkaz:
https://doaj.org/article/b9f52fa6cc0b443bb3d50ee68ac1e6d9
Autor:
Wen Li, Jiali Huang, Chen Shen, Weiye Jiang, Xi Yang, Jingxuan Huang, Yueqing Gu, Zhiyu Li, Yi Ma, Jinlei Bian
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 14, Iss 2, Pp 751-764 (2024)
Recent progress in targeted metabolic therapy of cancer has been limited by the considerable toxicity associated with such drugs. To address this challenge, we developed a smart theranostic prodrug system that combines a fluorophore and an anticancer
Externí odkaz:
https://doaj.org/article/87a2c5e865a749c483e6e2e55671671b
Autor:
Junyu Lin, Dejiang Pang, Chunyu Li, Ruwei Ou, Yujiao Yu, Yiyuan Cui, Jingxuan Huang, Huifang Shang
Publikováno v:
Therapeutic Advances in Neurological Disorders, Vol 17 (2024)
Background: The calcium channel has been considered to have great potential as a drug target for neuroprotective therapy in Parkinson’s disease (PD), but previous studies yielded inconsistent results. Objectives: This study aimed to conduct a syste
Externí odkaz:
https://doaj.org/article/f4b4ff81d14e474b8de719627fb93663
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundEpidemiological studies have provided evidence suggesting an association between Alzheimer’s disease (AD) and various oral manifestations. However, conflicting conclusions have been drawn, and whether a causal association truly exists rem
Externí odkaz:
https://doaj.org/article/6b97b642f0594f5cbd774ea4402cf790
Publikováno v:
Stem Cell Research, Vol 75, Iss , Pp 103305- (2024)
A variant of the phospholipase A2 group VI gene (PLA2G6, PARK14) has been found to cause early-onset Parkinson’s disease (EOPD). In this study, we reprogrammed peripheral blood mononuclear cells from a 39-year-old patient with EOPD carrying a homoz
Externí odkaz:
https://doaj.org/article/33a5c2b53f4f4cae8bfb783b0989e1cb
Publikováno v:
EURASIP Journal on Wireless Communications and Networking, Vol 2023, Iss 1, Pp 1-19 (2023)
Abstract The densification of the orthogonal frequency division multiplexing (OFDM) based fifth-generation communication systems, as well as the requirement of integrating sensing and communication functionalities, has promoted the development of int
Externí odkaz:
https://doaj.org/article/753da9341ae440549c84bc143b32bccb
Publikováno v:
BIO Integration, Vol 5, Iss 1 (2024)
Background: Circular RNAs (circRNAs) regulate tumor development by interacting with microRNAs. However, limited research has been conducted on the roles of circRNAs in gliomas. Therefore, we sought to demonstrate the function and molecular mechanism
Externí odkaz:
https://doaj.org/article/b3ce780fed1e4cab95195047178fe25b
Autor:
Chunyu Li, Yanbing Hou, Qianqian Wei, Junyu Lin, Zheng Jiang, Qirui Jiang, Tianmi Yang, Yi Xiao, Jingxuan Huang, Yangfan Cheng, Ruwei Ou, Kuncheng Liu, Xueping Chen, Wei Song, Bi Zhao, Ying Wu, Bei Cao, Yongping Chen, Huifang Shang
Publikováno v:
Human Genomics, Vol 17, Iss 1, Pp 1-6 (2023)
Abstract Background Recently, several rare variants of SPTLC1 were identified as disease cause for juvenile amyotrophic lateral sclerosis (ALS) by disrupting the normal homeostatic regulation of serine palmitoyltransferase (SPT). However, further exp
Externí odkaz:
https://doaj.org/article/66c0b1fdf29e423e845e62bbdc2cd24e