Zobrazeno 1 - 10
of 34
pro vyhledávání: '"JIM SILVER"'
Autor:
Eduardo Cuevas, Nathan F. Putman, Abigail Uribe-Martínez, Melania C. López-Castro, Vicente Guzmán-Hernández, Sandra A. Gallegos-Fernández, María de los Ángeles Liceaga-Correa, Jorge A. Trujillo-Córdova, Raúl de Jesús González-Díaz-Mirón, Ana Negrete-Phillipe, Héctor H. Acosta-Sánchez, Rosa C. Martínez-Portugal, Martha López-Hernández, Patricia Huerta-Rodríguez, Jim Silver
Publikováno v:
Frontiers in Marine Science, Vol 7 (2020)
In the Gulf of Mexico, the bulk of published studies for sea turtles have focused on northern (United States) waters where economic resources are centered, with fewer studies in the southern portion of the basin, resulting in significant knowledge ga
Externí odkaz:
https://doaj.org/article/f0278723e0b9481c8609c4cb508202fc
Autor:
Patrik Engström, K. Syam Krishnan, Bidong D. Ngyuen, Erik Chorell, Johan Normark, Jim Silver, Robert J. Bastidas, Matthew D. Welch, Scott J. Hultgren, Hans Wolf-Watz, Raphael H. Valdivia, Fredrik Almqvist, Sven Bergström
Publikováno v:
mBio, Vol 6, Iss 1 (2015)
ABSTRACT In a screen for compounds that inhibit infectivity of the obligate intracellular pathogen Chlamydia trachomatis, we identified the 2-pyridone amide KSK120. A fluorescent KSK120 analogue was synthesized and observed to be associated with the
Externí odkaz:
https://doaj.org/article/00303facf7d845949d710878fb025781
Autor:
Jim Silver, Ya-Fang Mei
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17532 (2011)
Replication-competent adenovirus type 5 (Ad5) vectors promise to be more efficient gene delivery vehicles than their replication-deficient counterparts, and chimeric Ad5 vectors that are capable of targeting CD46 are more effective than Ad5 vectors w
Externí odkaz:
https://doaj.org/article/0d97f97cdcd34813b7edc887dcf18440
Autor:
Jim Silver, Haitham Elbir, Katarina Vielfort, Fredrik Almqvist, Carlos Núñez-Otero, Pardeep Singh, Wael Bahnan, Sven Bergström, Åsa Gylfe
Publikováno v:
Antimicrob Agents Chemother
Chlamydia trachomatis is a strict intracellular bacterium that causes sexually transmitted infections and eye infections that can lead to lifelong sequelae. Treatment options are limited to broad-spectrum antibiotics that disturb the commensal flora
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85b41f797c2f81af3d43761c188665f9
https://doi.org/10.1128/aac.01826-20
https://doi.org/10.1128/aac.01826-20
Autor:
Pardeep Singh, Sven Bergström, Jim Silver, Katarina Vielfort, Fredrik Almqvist, Wael Bahnan, Anders E. G. Lindgren, Åsa Gylfe, Emma Wede, Martina Kulén, James A. D. Good, Richard Svensson, Andrew G. Cairns, Carlos Núñez-Otero
Publikováno v:
MedChemComm
Methyl sulfonamide substituents effectively improve the pharmacokinetic properties of bicyclic 2-pyridones, a new class of Chlamydia trachomatis infectivity inhibitors.
Chlamydia trachomatis infections are a global health problem and new approac
Chlamydia trachomatis infections are a global health problem and new approac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c24e219c628fe409a53bb793792b9e80
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166479
http://urn.kb.se/resolve?urn=urn:nbn:se:umu:diva-166479
Publikováno v:
Virology. 497:198-210
Conventional adenovirus vectors harboring E1 or E3 deletions followed by the insertion of an exogenous gene show considerably reduced virion stability. Here, we report strategies to generate complete replication-competent Ad11p(RCAd11p) vectors that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bbeec4de692005d6c0bf40022f44423
https://doi.org/10.1016/j.virol.2016.07.026
https://doi.org/10.1016/j.virol.2016.07.026
Autor:
Olli Salin, Patrik Engström, Wael Bahnan, Åsa Gylfe, James A. D. Good, Fredrik Almqvist, Sven Bergström, Carlos Núñez-Otero, K. Syam Krishnan, Richard Svensson, Jim Silver, Per Artursson
Publikováno v:
Journal of Medicinal Chemistry. 59:2094-2108
The bacterial pathogen Chlamydia trachomatis is a global health burden currently treated with broad-spectrum antibiotics which disrupt commensal bacteria. We recently identified a compound through phenotypic screening that blocked infectivity of this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f62725a446ad67d1430ec5dc5033545
https://doi.org/10.1021/acs.jmedchem.5b01759
https://doi.org/10.1021/acs.jmedchem.5b01759
Autor:
Åsa Gylfe, Esmee de Groot, Fredrik Almqvist, Emma Wede, Martina Kulén, Carlos Núñez-Otero, Jim Silver, K. Syam Krishnan, Wael Bahnan, James A. D. Good, Ingela Nilsson, Sven Bergström
Publikováno v:
Journal of medicinal chemistry. 60(22)
Chlamydia trachomatis is a global health burden due to its prevalence as a sexually transmitted disease and as the causative agent of the eye infection trachoma. We recently discovered 3-amido thiazolino 2-pyridones which attenuated C. trachomatis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1faf7f81534f7f6ea89bf88028a31d1b
https://pubmed.ncbi.nlm.nih.gov/29053275
https://pubmed.ncbi.nlm.nih.gov/29053275
Autor:
Hanna Uvell, Åsa Gylfe, Mikael Elofsson, Anders E. G. Lindgren, Olli Salin, Sania Marwaha, Jim Silver
Publikováno v:
Antimicrobial Agents and Chemotherapy. 58:2968-2971
Antibacterial compounds with novel modes of action are needed for management of bacterial infections. Here we describe a high-content screen of 9,800 compounds identifying acylated sulfonamides as novel growth inhibitors of the sexually transmitted p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2790e1c8b445bcdff7870bc20c712adc
https://doi.org/10.1128/aac.02015-13
https://doi.org/10.1128/aac.02015-13