Zobrazeno 1 - 10
of 332
pro vyhledávání: '"JIANWEI XIE"'
Publikováno v:
Green Chemistry Letters and Reviews, Vol 17, Iss 1 (2024)
Cu(im)2-derived Cu@N–C(600) catalyst has been efficiently utilized for the preparation of N-tosyl(H)−2-substituted indoles through one-pot domino Sonogashira coupling-cyclization reactions between N-tosyl(acetyl)−2-iodo anilines and aryl acetyl
Externí odkaz:
https://doaj.org/article/b8c1261735cb44c288e5a280cdad8547
Autor:
Longlong Cao, Guangtan Lin, Denghui Fan, Kai Weng, Yujing Chen, Jiabin Wang, Ping Li, Chaohui Zheng, Changming Huang, Jianwei Xie
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114446- (2024)
Summary: The gene encoding the NUAK family kinase 1 (NUAK1) is frequently amplified and its expression is upregulated, activating oncogenic signaling in various cancers. However, little is known about its role in gastric cancer (GC). We investigate t
Externí odkaz:
https://doaj.org/article/7e58739b58094aa0a275831fb9161ac5
Autor:
Minmin Qu, Jia Chen, Bin Xu, Qinyun Shi, Shujing Zhao, Zhaoxia Wang, Zhi Li, Bo Ma, Hua Xu, Qinong Ye, Jianwei Xie
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Chemotherapy has already proven widely effective in treating cancer. Chemotherapeutic agents usually include DNA damaging agents and non-DNA damaging agents. Assessing genotoxic effect is significant during chemotherapy drug development, since the ab
Externí odkaz:
https://doaj.org/article/aedd148a29764bfe9ac470707d745799
Publikováno v:
Molecules, Vol 29, Iss 14, p 3257 (2024)
Genotoxic substances widely exist in the environment and the food supply, posing serious health risks due to their potential to induce DNA damage and cancer. Traditional genotoxicity assays, while valuable, are limited by insufficient sensitivity, sp
Externí odkaz:
https://doaj.org/article/c0af57f8e1b94c1a8857e9116449e87f
Publikováno v:
Toxins, Vol 16, Iss 7, p 312 (2024)
Abrin and ricin, both type II ribosome-inactivating proteins, are toxins of significant concern and are under international restriction by the Chemical Weapons Convention and the Biological and Toxin Weapons Convention. The development of a rapid and
Externí odkaz:
https://doaj.org/article/6b51d96499ac4112a5fa1271807d987a
Publikováno v:
Toxins, Vol 16, Iss 6, p 237 (2024)
Ricin and abrin are highly potent plant-derived toxins, categorized as type II ribosome-inactivating proteins. High toxicity, accessibility, and the lack of effective countermeasures make them potential agents in bioterrorism and biowarfare, posing s
Externí odkaz:
https://doaj.org/article/ec593fa94c4047c486fd6d4e618a48fd
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
ObjectiveThis systematic review and network meta-analysis sought to determine the efficacy of different intensities of transcranial direct current stimulation (tDCS) in patients with dysphagia after stroke to improve swallowing function.MethodsRandom
Externí odkaz:
https://doaj.org/article/fc8b7ba788c14b7aa668fdfc532e9a3a
Autor:
Luyuan Qin, Junshan Han, Chuang Wang, Bin Xu, Deyun Tan, Song He, Lei Guo, Xiaochen Bo, Jianwei Xie
Publikováno v:
Frontiers in Plant Science, Vol 13 (2022)
IntroductionCastor bean or ricin-induced intoxication or terror events have threatened public security and social safety. Potential resources or materials include beans, raw extraction products, crude toxins, and purified ricin. The traceability of t
Externí odkaz:
https://doaj.org/article/d9e484d60c434cd7b047b6104f4a7192
Autor:
Hongling Zhao, Minmin Qu, Yuchen Li, Ke Wen, Hua Xu, Man Song, Dafei Xie, Xingkun Ao, Yihao Gong, Li Sui, Hua Guan, Pingkun Zhou, Jianwei Xie
Publikováno v:
Frontiers in Public Health, Vol 10 (2022)
Exposure to environmental ionizing radiation (IR) is ubiquitous, and large-dose exposure to IR is known to cause DNA damage and genotoxicity which is associated with an increased risk of cancer. Whether such detrimental effects are caused by exposure
Externí odkaz:
https://doaj.org/article/812d1cc770bf4680b9a51c0c76d987e3
Publikováno v:
Toxins, Vol 15, Iss 8, p 490 (2023)
The highly toxic plant toxin ricin is one of the most known threatening toxins. Accurate and sensitive biosensing methods for the first emergency response and intoxication treatment, are always pursued in the biodefense field. Screening affinity mole
Externí odkaz:
https://doaj.org/article/122043653ff24ec4b2b037b5651cc8a3