Zobrazeno 1 - 10
of 34
pro vyhledávání: '"JIANLIN GENG"'
Autor:
Xiaolong Li, Kunjie Zheng, Lifang Liu, Tingxue Zhang, Wei Gu, Xiaoyu Hou, Jianlin Geng, Guangyao Song
Publikováno v:
Frontiers in Endocrinology, Vol 15 (2024)
IntroductionMetabolic dysfunction-associated fatty liver disease (MAFLD) is closely associated with serum fibroblast growth factor (FGF) 21; however, previous studies have typically focused on the static fasting state, and the relationships between p
Externí odkaz:
https://doaj.org/article/e23224c126a44c1e9296bd5e144dff83
Autor:
Wei Gu, Linquan Yang, Xing Wang, Jianlin Geng, Xiaolong Li, Kunjie Zheng, Yunpeng Guan, Xiaoyu Hou, Chao Wang, Guangyao Song
Publikováno v:
Kidney & Blood Pressure Research, Pp 1-9 (2022)
Background: Diabetic kidney disease is a major cause of global end-stage renal diseases. Ectopic lipid deposition in the renal tissues of diabetic kidney disease is one major factor leading to renal fibrosis and chronic kidney disease. Pterostilbene
Externí odkaz:
https://doaj.org/article/bdf5fdb7ff7147c3a8ba62692ea0fa18
Autor:
Boyoung Shin, Gloria A. Benavides, Jianlin Geng, Sergei B. Koralov, Hui Hu, Victor M. Darley-Usmar, Laurie E. Harrington
Publikováno v:
Cell Reports, Vol 30, Iss 6, Pp 1898-1909.e4 (2020)
Summary: Understanding metabolic pathways that regulate Th17 development is important to broaden therapeutic options for Th17-mediated autoimmunity. Here, we report a pivotal role of mitochondrial oxidative phosphorylation (OXPHOS) for lineage specif
Externí odkaz:
https://doaj.org/article/89d9c913ac614a27a667303b79e29b6a
Autor:
Jianlin Geng, Xuejun Li, Zhiqiang Ning, Haixiang Cao, Weihong Song, Xin Gao, Zunhai Zhou, Yangang Wang, He Yao, Hanqing Cai, Lian Guo, Wei Li, Xinsheng Li, Gangyi Yang, Zhiguang Zhou, Desi Pan, Fuyan Shi, Hongmei Li, Weiping Jia, Yanjun Liu, Linong Ji, Hui Fang, Haoming Tian, Shuying Li, Yancheng Xu, Qifu Li, Kuanzhi Liu, Lu Xianping, Tao Yang, Qiuhe Ji, Qing Su, Wenbo Wang
Publikováno v:
Science Bulletin. 66:1571-1580
Chiglitazar (Carfloglitazar) is a novel non-thiazolidinedione (TZD) structured peroxisome proliferator-activated receptor (PPAR) pan-agonist that has shown promising effects on glycemic control and lipid regulation in patients with type 2 diabetes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::275485429bd15a01ce729a6280acb071
https://doi.org/10.1016/j.scib.2021.03.019
https://doi.org/10.1016/j.scib.2021.03.019
Autor:
Haiyan Liu, Yuwei Zhang, Liujun Fu, Yan Li, Daoxiong Chen, Lihui Zhang, Jianlin Geng, Guijun Qin, Tao Zhang, Zilin Sun, Jianjun Zou, Weiping Lu, Yadong Sun, Yushan Guo, Juming Lu, Ping Li, Hailong Zheng, Yanbing Li, Li Qin
Publikováno v:
Diabetes, Obesity and Metabolism. 23:1111-1120
AIM To evaluate henagliflozin, a novel sodium-glucose co-transporter-2 inhibitor, as monotherapy in patients with type 2 diabetes and inadequate glycaemic control with diet and exercise. MATERIALS AND METHODS This multicentre trial included a 24-week
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff44a3518158f35704abd31d7d7577e
https://doi.org/10.1111/dom.14314
https://doi.org/10.1111/dom.14314
Autor:
Jianping, Xu, Hongwei, Ling, Jianlin, Geng, Yanli, Huang, Ying, Xie, Huiping, Zheng, Huikun, Niu, Tianhao, Zhang, Jing, Yuan, Xinhua, Xiao
Publikováno v:
Diabetes, obesitymetabolism. 24(11)
To evaluate the efficacy and safety of DBPR108 (prusogliptin), a novel dipeptidyl peptidase-4 (DPP-4) inhibitor, as an add-on therapy in patients with type 2 diabetes (T2D) that is inadequately controlled with metformin.In this 24-week, multi-centre,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c3092a5d34b4f301e6f1e62e493ae268
https://pubmed.ncbi.nlm.nih.gov/35791646
https://pubmed.ncbi.nlm.nih.gov/35791646
Publikováno v:
Evidence-based complementary and alternative medicine : eCAM. 2022
Objective. The aim of the study is to evaluate the application value of three-dimensional speckle tracking imaging (3D-STI) and combined detection of thyroid autoantibodies and hormones in the diagnosis and treatment of Graves’ disease. Methods. A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5d1a3f12938b4785fe888d0a611f76b
https://pubmed.ncbi.nlm.nih.gov/35845595
https://pubmed.ncbi.nlm.nih.gov/35845595
Autor:
Wei Gu, Xing Wang, Huanfen Zhao, Jianlin Geng, Xiaolong Li, Kunjie Zheng, Yunpeng Guan, Xiaoyu Hou, Chao Wang, Guangyao Song
Publikováno v:
European journal of pharmacology. 918
Diabetic kidney disease (DKD) is a common microvascular complication of diabetes, and previous studies have shown that lipid deposits in the kidneys can lead to diabetic kidney damage. Resveratrol reduces circulating glucose and lipid concentrations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d8f0b469ae962c2aef920ec5b304095
https://pubmed.ncbi.nlm.nih.gov/35090936
https://pubmed.ncbi.nlm.nih.gov/35090936
Publikováno v:
International journal of clinical practice. 2022
Background and Aims. Previous studies on the effects of resveratrol on metabolic indicators reported contradictory findings, and these indicators have not been frequently studied in patients with type 2 diabetes. In this study, we aimed to examine th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9835f138cd873383517d0b9d171b2d0a
https://pubmed.ncbi.nlm.nih.gov/35685602
https://pubmed.ncbi.nlm.nih.gov/35685602
Autor:
Emily Smith, Bi Shi, Paul G. Thomas, Hui Hu, Braxton Greer, Yin Hu Wang, Hairong Wei, Melanie Pittman, Jianlin Geng, Olaf Kutsch
Publikováno v:
The Journal of Immunology. 202:2991-2998
T follicular helper (Tfh) cells are essential for germinal center B cell responses. The molecular mechanism underlying the initial Tfh cell differentiation, however, is still incompletely understood. In this study, we show that in vivo, despite enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d9bf60019acc4a796d87a4c0c997ab1f
https://doi.org/10.4049/jimmunol.1801626
https://doi.org/10.4049/jimmunol.1801626