Zobrazeno 1 - 10
of 105
pro vyhledávání: '"JIANGE ZHANG"'
Publikováno v:
Redox Biology, Vol 76, Iss , Pp 103324- (2024)
The polarization phenotype of microglia is critical in the progression of Parkinson's disease (PD). Molecules that can polarize microglia toward the M2 phenotype represent a promising class of compounds for anti-PD medications. Z-ligustilide (ZLG) is
Externí odkaz:
https://doaj.org/article/7eed960ef64a47b693e64cca430a9ed4
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Conventional knowledge graph representation learn the representation of entities and relations by projecting triples in the knowledge graph to a continuous vector space. The vector representation increases the precision of link prediction an
Externí odkaz:
https://doaj.org/article/3e58d62feeab444eb77e0bb2eddcc116
Autor:
Junchao Tan, Guoqiang Lin, Rui Zhang, Yuting Wen, Chunying Luo, Ran Wang, Feiyun Wang, Shoujiao Peng, Jiange Zhang
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1179 (2024)
Bufotalin (BT), a major active constituent of Chansu, has been found to possess multiple pharmacological activities. Although previous studies have shown that BT could inhibit the growth of glioblastoma (GBM), the safety of BT in vivo and the potenti
Externí odkaz:
https://doaj.org/article/e7f7eb1e9d30406d9853e60041e7d822
Autor:
Jiange Zhang, Ning Ding, Xue Cao, Shuting Zang, Ying Ren, Lijie Qin, Lijun Xu, Yanwei Cheng, Hongyan Li
Publikováno v:
Frontiers in Public Health, Vol 12 (2024)
BackgroundPrehospital emergency care is a critical but often understudied aspect of healthcare. Patient vulnerability in this setting can significantly impact outcomes. The aim of this study was to investigate the vulnerability status and to determin
Externí odkaz:
https://doaj.org/article/51903d0227e14e56a28aba7c8c95ffba
Publikováno v:
BMC Medical Genomics, Vol 16, Iss 1, Pp 1-14 (2023)
Abstract Apoptosis has been discovered as a mechanism of cell death. The purpose of this study is to identify the diagnostic signature factors related to bladder cancer (BLCA) through apoptosis related genes (ARGs). Clinicopathological parameters and
Externí odkaz:
https://doaj.org/article/69302f4e5a26410a9e0b16f5d9ee69f1
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundEmergency Departments (EDs) play a crucial role in providing immediate medical care, particularly in densely populated countries like China. While previous research has predominantly focused on well-funded urban hospitals, this study offers
Externí odkaz:
https://doaj.org/article/e52de16a383944bcaacd0630b14e3f46
Autor:
Jiange Zhang, Lei Yang, Xue Cao, Ying Ren, Xu Han, Shuting Zang, Fangfang Cai, Lijun Xu, Lijie Qin, Peirong Zhang, Yanwei Cheng
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
BackgroundThe aim of this study was to investigate the current state of disaster preparedness and to determine associated factors among emergency nurses from tertiary hospitals in Henan Province of China.MethodsThis multicenter descriptive cross-sect
Externí odkaz:
https://doaj.org/article/b150bd614e864e94a73ee551eec23438
Publikováno v:
Frontiers in Surgery, Vol 9 (2023)
PurposeThere is evidence that the Crystallin Alpha B (CRYAB) gene is involved in the regulation of the tumor microenvironment and influences tumor prognosis in some cancers. However, the role of CRYAB gene in prognosis and immunology in pan-cancer is
Externí odkaz:
https://doaj.org/article/12491ce2bb2d4eaf8f6256f63e085bb1
Autor:
Qianfei Cui PhD, Peng Song PhD, Tiancheng Ma PhD, Zefeng Wang PhD, Xiaojing Lu MS, Yongjia Shi MS, Fang Zhang PhD, Guoqiang Lin PhD, Jiajia Dong PhD, Jiange Zhang PhD
Publikováno v:
Technology in Cancer Research & Treatment, Vol 21 (2022)
Objective: Traditional chemical synthesis methods are cumbersome and inefficient. In this study, a novel antitumor molecule, 4-(4-(3-((6,7-bis(2-methoxyethoxy)quinazolin-4-yl)amino)phenyl)-1H-1,2,3-triazol-1-yl)phenyl sulfurofluoridate (P19G1), was i
Externí odkaz:
https://doaj.org/article/64c3a1a1a46d406ab538bb05860680f7
Autor:
Yuying Zhu, Liuqing Yang, Jiazhen Xu, Xiyan Yang, Pengwei Luan, Qianfei Cui, Pei Zhang, Feiyun Wang, Ruixiang Li, Xinyue Ding, Lixian Jiang, Guoqiang Lin, Jiange Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 8, Pp 1414-1425 (2020)
HuR (human antigen R), an mRNA-binding protein responsible for poor prognosis in nearly all kinds of malignancies, is a potential anti-tumor target for drug development. While screening HuR inhibitors with a fluorescence polarization (FP) based high-
Externí odkaz:
https://doaj.org/article/ad32284261d84227a6532988852a0e08